Abstract
Rapamycin is a naturally occurring antibiotic, immunosuppressant and anti-graft-rejection agent which was isolated from broth cultures of Streptomyces hydroscopicus (NRRL 5491) endemic to the Easter Island soil samples in Japan in 1975. The review focuses on the degradative and synthetic studies of this novel and challenging structure.
Current Organic Chemistry
Title:Degradative and Synthetic Studies on Rapamycin- A Potent Immunosuppressant
Volume: 2 Issue: 3
Author(s): Afgan Farooq, Shazia Anjum, M. Iqbal Choudhary and Atta-ur-Rahman*
Affiliation:
- H.E.J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan
Abstract: Rapamycin is a naturally occurring antibiotic, immunosuppressant and anti-graft-rejection agent which was isolated from broth cultures of Streptomyces hydroscopicus (NRRL 5491) endemic to the Easter Island soil samples in Japan in 1975. The review focuses on the degradative and synthetic studies of this novel and challenging structure.
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Cite this article as:
Farooq Afgan, Anjum Shazia, Choudhary M. Iqbal and Atta-ur-Rahman *, Degradative and Synthetic Studies on Rapamycin- A Potent Immunosuppressant, Current Organic Chemistry 1998; 2 (3) . https://dx.doi.org/10.2174/1385272802666220128195617
DOI https://dx.doi.org/10.2174/1385272802666220128195617 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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