Abstract
The [4 + 3] cycloadditions of oxyallyls and related allyl cations to 1,3-dienes have been widely utilized for the stereocontrolled construction of seven-membered carbocycles. By virtue of the spectator skeleton, the key variant of utilizing cyclic oxyallyls, i.e., by embedding an oxyallyl function in cyclic compounds, provides a conceptually attractive and operationally efficient route to other medium-sized carbocycles and heterocycles in addition to seven-membered rings. The resulting architecturally complex, polycyclic cycloadducts contain not only sufficient functionality, but also well defined facial differentiation useful for subsequent elaboration.
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Chemistry and Biology of Carbohydrates
Carbohydrates are one of the most abundant natural products and are considered to be extremely important biomolecules for their ever-increasing impact on chemistry and biology. Their role in several important biological processes, notably energy storage, transport, modulation of protein function, intercellular adhesion, malignant transformation, signal transduction, viral, and bacterial cell ...read more
Cutting-edge technology for the development of electrochemical sensors
Electrochemistry based point of care diagnostics is a powerful tool which can revolutionize the current concept of personalize health care industry. There have been several efforts to amalgamate cutting edge technologies (nanotechnology, surface technology, anti-biofouling strategies) while developing assays. The success of each electrochemical sensor is very dependable upon how ...read more
Electrochemical C-X bond formation
Conventional methods for carrying out carbon–X bond formation are typically conducted at harsh reaction conditions, and rely on expensive catalysts as well as the use of stoichiometric, and perhaps toxic, oxidants. In this regard, electrochemical synthesis has recently been recognized as a sustainable and scalable strategy for the construction of ...read more
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