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Current Drug Research Reviews

Editor-in-Chief

ISSN (Print): 2589-9775
ISSN (Online): 2589-9783

Mini-Review Article

Clinical Efficacy of Remdesivir and Favipiravir in the Treatment of COVID-19 Patients: Scenario so far

Author(s): Manisha Saini, Minakshi Rana, Karun Bhatti, Rina Das*, Dinesh Kumar Mehta and Ram Mohan Chidurala

Volume 14, Issue 1, 2022

Published on: 06 August, 2021

Page: [11 - 19] Pages: 9

DOI: 10.2174/2589977513666210806122901

Price: $65

Abstract

The novel SARS-CoV-2 is a new disease that has caused severe destruction to human lives across the globe, including infection, mortality and financial crises, for which, scientific researchers have been directed towards the development of treatment and controlling measures against coronavirus. Currently, there has been no approved drug for the treatment of the disease, but several antiviral drugs have shown therapeutic effects from which, remdesivir and favipiravir are two such drugs. These drugs have shown some therapeutic potential in the treatment of COVID-19 by inhibiting viral enzyme RNA-dependent RNA polymerase. The purpose of this systematic review is to provide an overview of the effectiveness of these two drugs based on the clinical trials reported in current published data.

Keywords: Coronavirus, COVID-19, SARS-CoV-2, antiviral, remdesivir, favipiravir.

Graphical Abstract
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