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Current Pharmaceutical Biotechnology

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ISSN (Print): 1389-2010
ISSN (Online): 1873-4316

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The Role of Lectin as Potential Biomarker in Ovarian Cancer

Author(s): Sangita Devi Oinam, Sunil Sing Senjam*, Rana Kamei and Joykishan Sharma Hanjabam

Volume 23, Issue 4, 2022

Published on: 25 June, 2021

Page: [478 - 485] Pages: 8

DOI: 10.2174/1389201022666210625125506

Price: $65

Abstract

Abstract: Lectin acts as an effective tool for screening potential biomarkers and gives an indication of highly valued research. Lectin offers the advantage of having the ability to recognize carbohydrate moiety of glycoprotein, peptidoglycan, glycosides, glycopeptides, lipopolysaccharide etc. makes powerful aid in detecting new cancer biomarkers in most complex tissues and fluids. The unique specificity of lectin in detecting single out anomalously expressed glycosylation pave lectin-based method that can often go down the line for future cancer biomarkers. This article explores the different types of lectin, their sources and possible application in masking the activity of ovarian cancer cells.

Keywords: Lectin, ovarian cancer, biomarker, glycosylation, tumors, glycosylated mucin antigen, N-acetyl galactosamine.

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