Abstract
Introduction: Herb, Zanthoxylum armatum DC., commonly called Indian prickly ash, and Nepal pepper (family Rutaceae), is widely utilized in the traditional medicinal system.
Objective: The current review provides requisite data for collecting descriptive information on the organoleptic, microscopical, ethnobotanical use, and phytochemicals and pharmacological properties of Z. armatum; therefore, it may help in forming a bridge between research gaps and the upcoming future findings for most of the researches.
Materials and Methods: The systematic literature survey was conducted using the PRISMA methodology. The collective information was gathered from books, renowned journals, and electronic databases including Science Direct, Web of Science, Scopus and PubMed from 1966 to 2020.
Results: Most of the bioactive metabolites are isolated and characterized till date, such as monoterpenes in essential oil and lignan components are reported to be present in the herbs. Several in vitro and in vivo pharmacological bioassays revealed the potential of Z. armatum having as possessing antimicrobial, antifungal, antibacterial, and hepatoprotective effects and so on.
Conclusion: Therefore, the current review summarizes the organoleptic, microscopy, phytochemistry and biological activities of Z. armatum, providing more emphasis on in vitro as well as in-vivo studies along with clinical research, helpful in exploring the potential efficacy of the plant.
Keywords: Flavonoids, GC, HPLC, lignans, phytochemistry, pharmacological activity.
Mini-Reviews in Medicinal Chemistry
Title:PRISMA Based Systematic Review: Pharmacognostic Study of Zanthoxylum armatum DC.
Volume: 21 Issue: 14
Author(s): Sonia Singh*, Aman Kumar and Bhupesh C. Semwal
Affiliation:
- Institute of Pharmaceutical Research, GLA University, Mathura-281406, Uttar Pradesh,India
Keywords: Flavonoids, GC, HPLC, lignans, phytochemistry, pharmacological activity.
Abstract:
Introduction: Herb, Zanthoxylum armatum DC., commonly called Indian prickly ash, and Nepal pepper (family Rutaceae), is widely utilized in the traditional medicinal system.
Objective: The current review provides requisite data for collecting descriptive information on the organoleptic, microscopical, ethnobotanical use, and phytochemicals and pharmacological properties of Z. armatum; therefore, it may help in forming a bridge between research gaps and the upcoming future findings for most of the researches.
Materials and Methods: The systematic literature survey was conducted using the PRISMA methodology. The collective information was gathered from books, renowned journals, and electronic databases including Science Direct, Web of Science, Scopus and PubMed from 1966 to 2020.
Results: Most of the bioactive metabolites are isolated and characterized till date, such as monoterpenes in essential oil and lignan components are reported to be present in the herbs. Several in vitro and in vivo pharmacological bioassays revealed the potential of Z. armatum having as possessing antimicrobial, antifungal, antibacterial, and hepatoprotective effects and so on.
Conclusion: Therefore, the current review summarizes the organoleptic, microscopy, phytochemistry and biological activities of Z. armatum, providing more emphasis on in vitro as well as in-vivo studies along with clinical research, helpful in exploring the potential efficacy of the plant.
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Cite this article as:
Singh Sonia *, Kumar Aman and Semwal C. Bhupesh , PRISMA Based Systematic Review: Pharmacognostic Study of Zanthoxylum armatum DC., Mini-Reviews in Medicinal Chemistry 2021; 21 (14) . https://dx.doi.org/10.2174/1389557521999201230200503
DOI https://dx.doi.org/10.2174/1389557521999201230200503 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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