Abstract
Enzyme-catalyzed cascade reactions have attracted an increasing attention with many advantages, such as environmental protection, high efficiency and no need for intermediate purification. The present overview has summarized enzymatic cascade benefit systems, including double-enzyme, multi-enzyme, and chemical-enzyme catalytic one-pot reactions. With the continuous developments in protein engineering, metabolic engineering, synthetic biology and systems biocatalysis, multi-step biotransformations will expand the scope of application, as well as enhance the biocatalytic efficiency.
Keywords: Biocatalysis, cascade reaction, enzyme, multi-step biotransformations, one-pot reactions, synthetic biology.
Mini-Reviews in Organic Chemistry
Title:One Pot Enzyme-Catalyzed Cascade Benefit Systems
Volume: 18 Issue: 3
Author(s): Chengjun Jiang*, Guilin Cheng, Fan Xu and Qi Wu
Affiliation:
- School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, Zhejiang,China
Keywords: Biocatalysis, cascade reaction, enzyme, multi-step biotransformations, one-pot reactions, synthetic biology.
Abstract: Enzyme-catalyzed cascade reactions have attracted an increasing attention with many advantages, such as environmental protection, high efficiency and no need for intermediate purification. The present overview has summarized enzymatic cascade benefit systems, including double-enzyme, multi-enzyme, and chemical-enzyme catalytic one-pot reactions. With the continuous developments in protein engineering, metabolic engineering, synthetic biology and systems biocatalysis, multi-step biotransformations will expand the scope of application, as well as enhance the biocatalytic efficiency.
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Cite this article as:
Jiang Chengjun *, Cheng Guilin , Xu Fan and Wu Qi , One Pot Enzyme-Catalyzed Cascade Benefit Systems, Mini-Reviews in Organic Chemistry 2021; 18 (3) . https://dx.doi.org/10.2174/1570193X17999200727203215
DOI https://dx.doi.org/10.2174/1570193X17999200727203215 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
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