Abstract
The heterocyclic compounds are the building blocks for the synthesis of the different biologically active compounds in the organic chemistry. Heterocyclic compounds have versatile synthetic applicability and biological activity. Pyrazole carboxylic acid derivatives are significant scaffold structures in heterocyclic compounds due to biologic activities such as antimicrobial, anticancer, inflammatory, antidepressant, antifungal anti-tubercular and antiviral, etc. The aim of this mini-review is an overview synthesis of pyrazole carboxylic acid derivatives and their biologic applications. The summarized literature survey presents biological activities of pyrazole carboxylic acid derivatives and their various synthetic methods in detail. This mini-review can be a guide to many scientists in medicinal chemistry.
Keywords: Antimicrobial activity, heterocyclic, bioactive properties, pharmacologic activity, pyrazole, synthesis.
Mini-Reviews in Organic Chemistry
Title:Pyrazole Carboxylic Acid and Derivatives: Synthesis and Biological Applications
Volume: 18 Issue: 1
Author(s): Adnan Cetin*
Affiliation:
- Department of Sciences, Faculty of Education, University of Mus Alparslan, Mus,Turkey
Keywords: Antimicrobial activity, heterocyclic, bioactive properties, pharmacologic activity, pyrazole, synthesis.
Abstract: The heterocyclic compounds are the building blocks for the synthesis of the different biologically active compounds in the organic chemistry. Heterocyclic compounds have versatile synthetic applicability and biological activity. Pyrazole carboxylic acid derivatives are significant scaffold structures in heterocyclic compounds due to biologic activities such as antimicrobial, anticancer, inflammatory, antidepressant, antifungal anti-tubercular and antiviral, etc. The aim of this mini-review is an overview synthesis of pyrazole carboxylic acid derivatives and their biologic applications. The summarized literature survey presents biological activities of pyrazole carboxylic acid derivatives and their various synthetic methods in detail. This mini-review can be a guide to many scientists in medicinal chemistry.
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Cite this article as:
Cetin Adnan *, Pyrazole Carboxylic Acid and Derivatives: Synthesis and Biological Applications, Mini-Reviews in Organic Chemistry 2021; 18 (1) . https://dx.doi.org/10.2174/1570193X17999200507094857
DOI https://dx.doi.org/10.2174/1570193X17999200507094857 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
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