Abstract
Recent progress in the nanotechnology sector has abetted to mitigate the
drawbacks associated with conventional therapies' limited effectiveness and medication
efficacy after the in vivo drug delivery. In this regard, graphene; a 2D nanomaterial; has
emerged as one of the wonder materials in medication delivery systems. Since the
discovery of its capabilities in a biological system in 2008, numerous improvements
and developments have been made till now in the therapeutic application of graphenebased materials. Additionally, it has been imparted with specific biological activities by
both covalent and non-covalent surface revamping which further improves their
biocompatibility and colloidal stability. Due to their hexagonal lattice and high surface
area, they possess the astounding ability to provide high drug loading capacity via
simple preparation methods, which makes them a more fecund material in comparison
with other drug delivery systems. The present chapter outlines the exclusive drug and
gene delivery applications of graphene-based materials and discusses their up-to-date
advances. The chapter also discusses in detail how the integration of graphene and
polymers makes them ideal as a delivery system in tissue engineering and nanomedicine for therapeutic approaches. The outlook presented here may help invoke deep
insights into the nanotechnology-based drug delivery system for future research.
Keywords: Graphene, Drug, Gene, Biocompatibility.