Contents

Recent Patents on Anti-Infective Drug Discovery, Volume 6 - Number 2

Foreword

, 6(2): 76

Leonard Amaral


DOI: 10.2174/157489111796064605




XDR-TB, What is it; How is it Treated; and why is Therapeutic Failure so High?

, 6(2): 77 - 83

Stephen H. Gillespie and Kasha Singh


DOI: 10.2174/157489111796064641




Effective Therapy with the Neuroleptic Thioridazine as an Adjunct to Second Line of Defence Drugs, and the Potential that Thioridazine Offers for New Patents that Cover a Variety of “New Uses”

, 6(2): 84 - 87

Leonard Amaral, Miguel Viveiros, Joseph Molnar and Jette E. Kristiansen


DOI: 10.2174/157489111796064542




Safety and Efficacy of Thioridazine as Salvage Therapy in Indian Patients with XDR-TB

, 6(2): 88 - 91

Zarir F. Udwadia, Tiyas Sen and Lancelot M. Pinto


DOI: 10.2174/157489111796064614




Thioridazine: The Good and the Bad

, 6(2): 92 - 98

Ruben H.K. Thanacoody


DOI: 10.2174/157489111796064588




Global Clinical Trials for the Treatment of TB with Thioridazine

, 6(2): 99 - 103

Martin J. Boeree


DOI: 10.2174/157489111796064533




The Broad-spectrum Antimycobacterial Activities of Phenothiazines, In Vitro: Somewhere in All of this there May be Patentable Potentials

, 6(2): 104 - 109

Jakko van Ingen


DOI: 10.2174/157489111796064623




Targeting the Human Macrophage with Combinations of Drugs and Inhibitors of Ca2+ and K+ Transport to Enhance the Killing of Intracellular Multi-Drug Resistant Mycobacterium tuberculosis (MDR-TB) - a Novel, Patentable Approach to Limit the Emergence of XDR-TB

, 6(2): 110 - 117

Marta Martins


DOI: 10.2174/157489111796064524




Inhibition of Drug Efflux in Mycobacteria with Phenothiazines and Other Putative Efflux Inhibitors

, 6(2): 118 - 127

Liliana Rodrigues, Jose A. Ainsa, Leonard Amaral and Miguel Viveiros


DOI: 10.2174/157489111796064579




New Patentable Use of an Old Neuroleptic Compound Thioridazine to Combat Tuberculosis: A Gene Regulation Perspective

, 6(2): 128 - 138

Noton K. Dutta, Kaushiki Mazumdar, Sujata G. Dastidar, Petros C. Karakousis and Leonard Amaral


DOI: 10.2174/157489111796064597




Latent Tuberculosis: Is There a Role for Thioridazine?

, 6(2): 139 - 146

Charles Sohaskey


DOI: 10.2174/157489111796064551




Direct Modification of Bioactive Phenothiazines by Exposure to Laser Radiation

, 6(2): 147 - 157

Mihail-Lucian Pascu, Viorel Nastasa, Adriana Smarandache, Andra Militaru, Ana Martins, Miguel Viveiros, Mihai Boni, Ionut R. Andrei, Alexandru Pascu, Angela Staicu, Joseph Molnar, Seamus Fanning and Leonard Amaral


DOI: 10.2174/157489111796064515




Targeting Hepatitis B Virus and Human Papillomavirus Induced Carcinogenesis: Novel Patented Therapeutics

, 6(2): 158 - 174

Rupinder K. Kanwar, Neha Singh, Sneha Gurudevan and Jagat R. Kanwar


DOI: 10.2174/157489111796064560




Commercial Development and Application of Type A Lantibiotics

, 6(2): 175 - 185

Shawanda Wilson-Stanford and Leif Smith


DOI: 10.2174/157489111796064632




Patent Selections

, 6(2): 186 - 188

Bentham Science Publishers


DOI: 10.2174/157489111796064650




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