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New Emirates Medical Journal

Volume 3, 2 Issues, 2022
ISSN: 0250-6882 (Online)
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Open Access Article

The Role of Chest High Resolution CT and RT-PCR in Diagnosis of Different Stages of Coronavirus (COVID-19) Pneumonia

Mohamed N.E. Kassem1, *, Doaa T. Masallat2
1 Department of Radiology, Damietta hospital, Al-Azhar University, Egypt and Czech Rehabilitation Hospital, Royal health Group, Al-Ain, UAE
2 Department of Medical Microbiology & Immunology, Faculty of Medicine, Mansoura University, Al-Mansoura, Egypt



The purpose of this study is to investigate how RT-PCR (real time–polymerase-chain-reaction) and chest High-Resolution Computed Tomography (HRCT) can detect COVID-19 (Coronavirus Disease 2019) disease in the early, progressive and severe stages, as well as patient’s outcome.


We perform a prospective study with chest HRCT on 206 patients with positive RT-PCR test. The patients were divided into three groups; early stage (100 patients), progressive stage (70 patients) and severe stage (36 patients).


The early stage involved typical category (COVID-19 Reporting and Data System, CO-RADS 5, 34 cases - 34%), indeterminate category (CO-RADS 3, six cases - 6%), atypical category (CO-RADS 4, ten cases - 10%) and normal chest HRCT imaging (CO-RADS 1, 50 cases - 50%). The progressive stage involved a typical category (CO-RADS 5, 70 cases, 100%), The severe stage involved a typical category (CO-RADS 5, 36 cases, 100%).


RT-PCR is the gold standard and specific tool for confirming COVID-19 infection. Combination of RT-PCR and chest HRCT is used for the early diagnosis of COVID-19 pneumonia. Chest HRCT is positive in 50% of patients in the early stage of COVID-19. Chest HRCT is not only detecting pulmonary parenchymal changes but also determining patient’s outcome in the progressive and severe stages of COVID-19 (CO-RADS 5). Patients with progressive stage will not need ventilator and patients with severe stage should receive ventilator.

Keywords: HRCT, RT-PCR, COVID-19, Ground glass opacities, Consolidation, Pneumonia.

Article Information

Identifiers and Pagination:

Year: 2021
Volume: 2
Issue: 2
First Page: 108
Last Page: 114
Publisher Id: nemj-2-108
DOI: 10.2174/0250688202666210405153628

Article History:

Received Date: 8/10/2020
Revision Received Date: 10/1/2021
Acceptance Date: 27/1/2021
Electronic publication date: 27/7/2021
Collection year: 2021

© 2021 Kassem and Masallat

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Radiology, Damietta Hospital, Al-Azhar University, Egypt and Czech Rehabilitation Hospital, Royal Health Group, Al-Ain, UAE Tel: 00971508903894;


Abdullah Shehab
Emirates Cardiac Society
Emirates Medical Association
(United Arab Emirates)
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Acceptance rate = 40%

Average review speed: 45 days average

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