Contents

Mini-Reviews in Medicinal Chemistry, Volume 7 - Number 10

Sphingolipid Signaling Pathways as Potential Therapeutic Targets in Gliomas

, 7(10): 984 - 990

James R. Van Brocklyn


DOI: 10.2174/138955707782110123




Recent Advances Towards New Anti-Infective Agents that Inhibit Cell Surface Protein Anchoring in Staphylococcus aureus and Other Gram-Positive Pathogens

, 7(10): 991 - 1000

N. Suree, M. E. Jung and R. T. Clubb


DOI: 10.2174/138955707782110097




The Toxic Conformation of the 42-residue Amyloid β Peptide and Its Relevance to Oxidative Stress in Alzheimers Disease

, 7(10): 1001 - 1008

K. Irie, K. Murakami, Y. Masuda, A. Morimoto, H. Ohigashi, H. Hara, R. Ohashi, K. Takegoshi, H. Fukuda, M. Nagao, T. Shimizu and T. Shirasawa


DOI: 10.2174/138955707782110187




High-Speed Screening and Quantitative SAR Analysis of Human ABC Transporter ABCG2 for Molecular Modeling of Anticancer Drugs to Circumvent Multidrug Resistance

, 7(10): 1009 - 1018

H. Saito, H. Hirano and T. Ishikawa


DOI: 10.2174/138955707782110169




Cell-Based Biosensors in Clinical Chemistry

, 7(10): 1019 - 1026

Spiridon E. Kintzios


DOI: 10.2174/138955707782110141




α-Fluorinated Ethers as “Exotic” Entity in Medicinal Chemistry

, 7(10): 1027 - 1034

Peter Jeschke, Eckhard Baston and Frederic R. Leroux


DOI: 10.2174/138955707782110150




Mechanisms of Action of DNA-Damaging Anticancer Drugs in Treatment of Carcinomas: Is Acute Apoptosis an “Off-Target” Effect?

, 7(10): 1035 - 1039

Aleksandra Mandic Havelka, Maria Berndtsson, Maria Hagg Olofsson, Maria C. Shoshan and Stig Linder


DOI: 10.2174/138955707782110196




Michael Acceptors as Cysteine Protease Inhibitors

, 7(10): 1040 - 1050

Maria M.M. Santos and Rui Moreira


DOI: 10.2174/138955707782110105




Symptom and Structure Modifying Properties of Chondroitin Sulfate in Osteoarthritis

, 7(10): 1051 - 1061

Jean-Yves Reginster, Florence Heraud, Brigitte Zegels and Olivier Bruyere


DOI: 10.2174/138955707782110088




Depsipeptide (FK228) as a Novel Histone Deacetylase Inhibitor: Mechanism of Action and Anticancer Activity

, 7(10): 1062 - 1069

Ewa Lech-Maranda, Ewa Robak, Anna Korycka and Tadeusz Robak


DOI: 10.2174/138955707782110178




Cyclin-Dependent Kinase 5 (Cdk5): A Potential Therapeutic Target for the Treatment of Neurodegenerative Diseases and Diabetes Mellitus

, 7(10): 1070 - 1074

Fan-Yan Wei and Kazuhito Tomizawa


DOI: 10.2174/138955707782110114




Synthesis of Compounds as Melatonin Agonists and Antagonists

, 7(10): 1075 - 1088

Peter J. Garratt and Andrew Tsotinis


DOI: 10.2174/138955707782110132




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