Contents

Mini-Reviews in Medicinal Chemistry, Volume 16 - Number 5

Editorial

Editorial (Thematic Issue: The Elephant in the Room: Targeting Ras for Therapeutic Development)

, 16(5): 343 - 344

Shuxing Zhang and Zhi Tan


DOI: 10.2174/138955751605160201155950




Past, Present, and Future of Targeting Ras for Cancer Therapies

, 16(5): 345 - 357

Zhi Tan and Shuxing Zhang


DOI: 10.2174/1389557515666151001154111




How to Target Activated Ras Proteins: Direct Inhibition vs. Induced Mislocalization

, 16(5): 358 - 369

Ethan J. Brock, Kyungmin Ji, John J. Reiners and Raymond R. Mattingly


DOI: 10.2174/1389557515666151001154002




RAS/Effector Interactions from Structural and Biophysical Perspective

, 16(5): 370 - 375

Ariel Erijman and Julia M. Shifman


DOI: 10.2174/1389557515666151001141838




Direct Inhibitors of Ras-Effector Protein Interactions

, 16(5): 376 - 382

Punit Upadhyaya, Walaa Bedewy and Dehua Pei


DOI: 10.2174/1389557515666151001141713




Getting a Handle on RAS-targeted Therapies: Cysteine Directed Inhibitors

, 16(5): 383 - 390

Minh V. Huynh and Sharon L. Campbell


DOI: 10.2174/1389557515666151001154352




Ras Dimer Formation as a New Signaling Mechanism and Potential Cancer Therapeutic Target

, 16(5): 391 - 403

Mo Chen, Alec Peters, Tao Huang and Xiaolin Nan


DOI: 10.2174/1389557515666151001152212




Advances on Semisynthesis, Total Synthesis, and Structure-Activity Relationships of Honokiol and Magnolol Derivatives

, 16(5): 404 - 426

Chun Yang, Xiaoyan Zhi and Hui Xu


DOI: 10.2174/1389557516666151120115558




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