Contents

Medicinal Chemistry, Volume 9 - Number 4

Graphical Abstract

Graphical Abstracts

, 9(4): i - vi


DOI: 10.2174/1573406411309040001




Novel Structurally Varied N-Alkyl 1,4-Dihydropyridines as ABCB1 Inhibitors: Structure-Activity Relationships, Biological Activity and First Bioanalytical Evaluation

, 9(4): 487 - 493

Andreas Hilgeroth, Christiane Baumert, Claudius Coburger, Marianne Seifert, Soren Krawczyk, Cornelius Hempel, Felix Neubauer, Martin Krug, Josef Molnar and Hermann Lage


DOI: 10.2174/1573406411309040002




Synthesis and ABCG2 Inhibitory Activity of Novel Fumitremorgin C Analogs – Specificity and Structure Activity Correlations

, 9(4): 494 - 509

Orsolya Szolomajer-Csikos, Erzsebet Beery, Levente Kosa, Zsuzsanna Rajnai, Marton Jani, Anasztazia Hetenyi, Katalin Tauber Jakab, Peter Krajcsi and Gabor K Toth


DOI: 10.2174/1573406411309040003




Parallel Synthesis of “Click” Chalcones as Antitubulin Agents

, 9(4): 510 - 516

Maleeruk Utsintong, Alberto Massarotti, Antonio Caldarelli and Sewan Theeramunkong


DOI: 10.2174/1573406411309040004




Antitumor Activity of Novel Benzensulfonamide Derivatives in View of their Physiochemical Properties Searched by Principal Component Analysis

, 9(4): 517 - 525

Mariusz Belka, Jaroslaw Slawinski, Lucyna Konieczna, Piotr Kawczak, Tomasz Ciesielski and Tomasz Baczek


DOI: 10.2174/1573406411309040005




Nanosized Tamoxifen-Porphyrin-Glucose [TPG] Conjugate: Novel Selective Anti-breast-cancer Agent, Synthesis and In Vitro Evaluations

, 9(4): 526 - 538

Massoud Amanlou, Zahra Heidari, Seyed Davar Siadat, Mohammad Reza Aghasadeghi, Masoud Ghorbani, Seyed Esmaeil Sadat Ebrahimi, Seyed Mehdi Sadat, Mehdi Hajmohammadi, Ali Jabbari Arabzadeh, Soheila Hekmat, Mahmood Alaei-Beirami, Alireza Azizi Saraji, Hadi Fathi Moghaddam, Mohammad Shafiee Alavidjeh, Seyed Ali Delbaz, Abolfazl Dashtbani-Roozbehani and Mehdi Shafiee Ardestani


DOI: 10.2174/1573406411309040006




Synthesis of Trans-(4-hydroxypyridine)(Ammine)Dichloroplatinum(II) and its Activity in the Human Ovarian Tumour Models

, 9(4): 539 - 544

Narjes Deqnah, Jun Qing Yu, Philip Beale, Keith Fisher and Fazlul Huq


DOI: 10.2174/1573406411309040007




The Synthesis, Structural Study and Anticancer Activity Evaluation of Emodin Derivatives Containing Conjugative Groups

, 9(4): 545 - 552

Wang Wen-Feng, Zhang Feng-Sen, Zhao Wen-Na, Bai Ze-Dong, Yang Hui-Jun, Shao Jing-Wei and Yuan Yao-Feng


DOI: 10.2174/1573406411309040008




Computer Aided Discovery of Potential Anti-inflammatory (S)-naproxen Analogs as COX-2 Inhibitors

, 9(4): 553 - 559

Nulgumnalli Manjunathaiah Raghavendra, Kota Ramakrishna, Vippula Sirisha, Pingli Divya and Alapati Venkateswara Rao


DOI: 10.2174/1573406411309040009




3D-QSAR Modeling of Non-peptide Antagonists for the Human Luteinizing Hormone-releasing Hormone Receptor

, 9(4): 560 - 570

Alain Tundidor-Camba, Julio Caballero and Deysma Coll


DOI: 10.2174/1573406411309040010




Imidazole Incorporated Semicarbazone Derivatives as a New Class of Anticonvulsants: Design, Synthesis and In-Vivo Screening

, 9(4): 571 - 580

Mohammad Amir, Israr Ali and Mohd. Zaheen Hassan


DOI: 10.2174/1573406411309040011




Synthesis and Biological Evaluation of Novel Pyrimido[4,5-b]quinoline-2,4- dione Derivatives as MDM2 Ubiquitin Ligase Inhibitors

, 9(4): 581 - 587

Xiaoxue Dou, Xin Li, Liu Tao, Chunqi Hu, Lei Zhang, Qiaojun He, Bo Yang and Yongzhou Hu


DOI: 10.2174/1573406411309040012




Synthesis of Benzophenonehydrazone Schiff Bases and their In Vitro Antiglycating Activities

, 9(4): 588 - 595

Khalid Mohammed Khan, Fazal Rahim, Nida Ambreen, Muhammad Taha, Momin Khan, Humaira Jahan, Najeebullah, Azizuddin Shaikh, Sarosh Iqbal, Shahnaz Perveen and Muhammad Iqbal Choudhary


DOI: 10.2174/1573406411309040013




New Quinolinyl–1,3,4–Oxadiazoles: Synthesis, In Vitro Antibacterial, Antifungal and Antituberculosis Studies

, 9(4): 596 - 607

Rahul V. Patel, Premlata Kumari and Kishor H. Chikhalia


DOI: 10.2174/1573406411309040014




In-Silico Analysis of Chromone Containing Sulfonamide Derivatives as Human Carbonic Anhydrase Inhibitors

, 9(4): 608 - 616

Zaheer Ul-Haq, Saman Usmani, Uzma Mahmood, Mariya al-Rashida and Ghulam Abbas


DOI: 10.2174/1573406411309040015




6-Chloro-7-methyl-3', 4'-dimethoxyflavone – a Potent Selective COX-2 Inhibitor

, 9(4): 617 - 623

Rafia Bashir, Kalim Javed, Shafiya Yaseen, Syed Ovais, Pooja Rathore, Hinna Hamid, M. S. Alam, Mohammed Samim, Surender Singh and Vinod Nair


DOI: 10.2174/1573406411309040016




Investigations Towards New Antidiabetic Drugs from Fungal Endophytes Associated with Salvadora Oleoides Decne

, 9(4): 624 - 632

Seema Dhankhar, Sandeep Dhankhar and Jaya Parkash Yadav


DOI: 10.2174/1573406411309040017




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