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Contents

Medicinal Chemistry, Volume 8 - Number 3


Synthesis and Biological Evaluation of 3΄-C-Ethynyl and 3΄-C-(1,4-disubstituted-1,2,3-triazolo) Double-Headed Pyranonucleosides

, 8(3): 320 - 329

Christos Kiritsis, Stella Manta, Ioannis Papasotiriou, Evdoxia Coutouli-Argyropoulou, Sakellarios Trakossas, Jan Balzarini and Dimitri Komiotis


DOI: 10.2174/157340612800786624


Substituted Urea Derivatives: A Potent Class of Antidepressant Agents

, 8(3): 330 - 336

Shahnaz Perveen, Sana Mustafa, Muhammad A. Khan, Ahsana Dar, Khalid M. Khan and Wolfgang Voelter


DOI: 10.2174/157340612800786615



SAR Analysis of New Dual Targeting Fluoroquinolones. Implications of the Benzenesulfonyl Group

, 8(3): 349 - 360

Marcelo J. Nieto, Adriana B. Pierini, Nidhi Singh, Christopher R. McCurdy, Ruben H. Manzo and aria R. Mazzieri


DOI: 10.2174/157340612800786633


S-Nitrosylation and Attenuation of Excessive Calcium Flux by Pentacycloundecane Derivatives

, 8(3): 361 - 371

Hendrik J.R. Lemmer, Jacques Joubert, Sandra van Dyk, Francois H. van der Westhuizen and Sarel F. Malan


DOI: 10.2174/1573406411208030361


CoMFA and CoMSIA Studies of 1,2-dihydropyridine Derivatives as Anticancer Agents

, 8(3): 372 - 383

Ismail Salama, Mohamed A. O. Abdel-Fattah, Marwa S. Hany, Shaimaa A. El-Sharif, Mahmoud A. M. El-Naggar, Rasha M. H. Rashied, Gary A. Piazza and Ashraf H. Abadi


DOI: 10.2174/157340612800786598



Four-Component Synthesis of 1,2-Dihydropyridine Derivatives and their Evaluation as Anticancer Agents

, 8(3): 392 - 400

Mohamed A. O. Abdel-Fattah, Mahmoud A. M. El-Naggar, Rasha M. H. Rashied, Bernard D. Gary, Gary A. Piazza and Ashraf H. Abadi


DOI: 10.2174/1573406411208030392



In vitro Anti-glycation and Anti-oxidant Properties of Synthesized Schiff Bases

, 8(3): 409 - 414

Sabina Jhaumeer-Laulloo, Minu Gupta Bhowon, Shabneez Mungur, Mohamad Fawzi Mahomoodally and Anwar Hussein Subratty


DOI: 10.2174/1573406411208030409


Synthesis and Antiglycation Activity of Kaempferol-3-O-rutinoside (Nicotiflorin)

, 8(3): 415 - 420

Sajan Lal Shyaula, Ghulam Abbas, Hina Siddiqui, Samina A. Sattar, M. Iqbal Choudhary and Fatima Z. Basha


DOI: 10.2174/1573406411208030415


Synthesis and β-Glucuronidase Inhibitory Potential of Benzimidazole Derivatives

, 8(3): 421 - 427

Khalid Mohammed Khan, Momin Khan, Nida Ambreen, Fazal Rahim, Shagufta Naureen, Shahnaz Perveen, M. Iqbal Choudhary and Wolfgang Voelter


DOI: 10.2174/1573406411208030421




2,4,6-Trichlorophenylhydrazine Schiff Bases as DPPH Radical and Super Oxide Anion Scavengers

, 8(3): 452 - 461

Khalid Mohammed Khan, Zarbad Shah, Viqar Uddin Ahmad, Momin Khan, Muhammad Taha, Fazal Rahim, Sajjad Ali, Nida Ambreen, Shahnaz Perveen, M. Iqbal Choudhary and Wolfgang Voelter


DOI: 10.2174/1573406411208030452




Synthesis and Biological Evaluation of the Salicylamide and Salicylic Acid Derivatives as Anti-Estrogen Agents

, 8(3): 481 - 490

Yasemin Dundar, Yasemin Ozatik, Orhan Ozatik, Volkan Ergin, Tijen Onkol, Adnan Menevse, Kevser Erol and M. Fethi Sahin


DOI: 10.2174/1573406411208030481





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