Contents

Medicinal Chemistry, Volume 6 - Number 6

Synthesis and Cellular Pharmacology Studies of a Series of 2-amino-3-aroyl-4-substituted Thiophene Derivatives

, 6(6): 329 - 343

Romeo Romagnoli, Pier Giovanni Baraldi, Maria Giovanna Pavani, Olga Cruz-Lopez, Ernest Hamel, Jan Balzarini, Eleonora Brognara, Cristina Zuccato and Roberto Gambari


DOI: 10.2174/157340610793563974




Synthesis, Testing and Structure-Activity Studies on a Library of 5-HT4 Ligands

, 6(6): 344 - 354

Amir Hanna-Elias, David T. Manallack, Alla Levit, William Nguyen, Fadi Ayad, Glen Perera, Marina Shapiro, Helen R. Irving, Ian M. Coupar and Magdy N. Iskander


DOI: 10.2174/157340610793563965




New Synthesis of Tic-Hydantoins Sigma-1 Ligands and Pharmacological Evaluation on Cocaine-Induced Stimulant Effects

, 6(6): 355 - 373

M. Toussaint, M.-A. Debreu-Fontaine, T. Maurice and P. Melnyk


DOI: 10.2174/157340610793563956




A Novel Access to Arylated and Heteroarylated Beta-Carboline Based PDE5 Inhibitors

, 6(6): 374 - 387

Nermin S. Ahmed, Bernard D. Gary, Gary A. Piazza, Heather N. Tinsley, Stefan Laufer and Ashraf H. Abadi


DOI: 10.2174/157340610793563992




Using Compound Similarity and Functional Domain Composition for Prediction of Drug-Target Interaction Networks

, 6(6): 388 - 395

Lei Chen, Zhi-Song He, Tao Huang and Yu-Dong Cai


DOI: 10.2174/157340610793563983




Anticancer Activity of the Ascidian Polyclinum Indicum against Cervical Cancer Cells (HeLa) Mediated through Apoptosis Induction

, 6(6): 396 - 405

Rajaian Pusphabai Rajesh, Maniramakrishnan Santhana Ramasamy and Annappan Murugan


DOI: 10.2174/157340610793564009




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