Contents

Medicinal Chemistry, Volume 5 - Number 3

Controlled Exploration of Structural Databases: The Case of Farnesyl Transferase Inhibitors

, 5(3): 208 - 215

A. Tizot, G. C. Tucker, A. Pierre, J. Hickman and S. Goldstein


DOI: 10.2174/157340609788185891




Polyamide Curvature and DNA Sequence Selective Recognition: Use of 4-Aminobenzamide to Adjust Curvature

, 5(3): 216 - 226

Jamie Lajiness, Alan Sielaff, Hilary Mackay, Toni Brown, Jerome Kluza, Binh Nguyen, W. David Wilson, Moses Lee and John A. Hartley


DOI: 10.2174/157340609788185945




Synthesis and In Vitro Anti-Lung Cancer Activity of Novel 1, 3, 4, 8- Tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-o ne Alkaloid Analogs

, 5(3): 227 - 236

Dwayaja H. Nadkarni, Feng Wang, Wei Wang, Elizabeth R. Rayburn, Scharri J. Ezell, Srinivasan Murugesan, Sadanandan E. Velu and Ruiwen Zhang


DOI: 10.2174/157340609788185873




Analysis of Pralidoxime in Serum, Brain and CSF of Rats

, 5(3): 237 - 241

Huba Kalasz, Eva Szoko, Tamas Tabi, Georg A. Petroianu, Dietrich E. Lorke, Abdulrab Omar, Salem Alafifi, Almerri Jasem and Kornelia Tekes


DOI: 10.2174/157340609788185882




Binding Mechanism of H5N1 Influenza Virus Neuraminidase with Ligands and its Implication for Drug Design

, 5(3): 242 - 249

Ke Gong, Lin Li, Jing-Fang Wang, Feng Cheng, Dong-Qing Wei and Kuo-Chen Chou


DOI: 10.2174/157340609788185936




Possible Drug Candidates for Alzheimers Disease Deduced from Studying their Binding Interactions with α7 Nicotinic Acetylcholine Receptor

, 5(3): 250 - 262

Ruo-Xu Gu, Hui Gu, Zhi-Yuan Xie, Jing-Fang Wang, Hugo R. Arias, Dong-Qing Wei and Kuo-Chen Chou


DOI: 10.2174/157340609788185909




Binding of CYP2C9 with Diverse Drugs and its Implications for Metabolic Mechanism

, 5(3): 263 - 270

Jing-Fang Wang, Jing-Yi Yan, Dong-Qing Wei and Kuo-Chen Chou


DOI: 10.2174/157340609788185954




Structure-Activity Relationships for Serotonin Transporter and Dopamine Receptor Selectivity

, 5(3): 271 - 278

Snezana Agatonovic-Kustrin, Paul Davies and Joseph V. Turner


DOI: 10.2174/157340609788185927




Olanzapine Does not Aggrevate Ischemic Neuronal Injury by Focal Cerebral Ischemia: A Dose Related Restriction of the Neuroprotective Effect?

, 5(3): 279 - 282

Burak Yulug and Ertugrul Kilic


DOI: 10.2174/157340609788185864




Synthesis, Structural Characterization and Antibacterial Activity of Novel 7β-{[3-(substituted phenyl)-2-propenoyl]amino}-3-[(2,5-dihydro-6-hydroxy- 2-methyl)-5-oxo-cis-triazin-3-yl]-thiomethyl-cefalosporins

, 5(3): 283 - 292

Zalua Rodriguez, Miguel A. Lopez, Maritza Gonzalez, Blanca Tolon, Loreta Nadal, Leonora Gonzalez, Herman Velez and Adamo Fini


DOI: 10.2174/157340609788185855




Synthesis and Comparison of Antimalarial Activity of Febrifugine Derivatives Including Halofuginone

, 5(3): 293 - 300

Bhupesh S. Samant and Mugdha G. Sukhthankar


DOI: 10.2174/157340609788185846




Stepwise Regression Analysis of the Determinants of Blood Tacrolimus Concentrations in Chinese Patients with Liver Transplant

, 5(3): 301 - 304

Z. Jin, W. x. Zhang, B. Chen, A. W. Mao and W. M. Cai


DOI: 10.2174/157340609788185918




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