Contents

Medicinal Chemistry, Volume 4 - Number 4

Allosteric Inhibition of [125I] ET-1 Binding to ETA Receptors by Aldoxime and Hydroxamic Acid Derivatives

, 4(4): 298 - 308

Musa Ahmed, Susanna Nencetti, Maria R. Mazzoni, Francesca Porchia, Federica Antonelli and Annalina Lapucci


DOI: 10.2174/157340608784872208




Methisergide Selective Inhibition of Opioid Acute Physical Dependence in Isolated Tissues

, 4(4): 309 - 312

Anna Capasso


DOI: 10.2174/157340608784872253




3D-QSAR CoMFA and CoMSIA Study on Benzodipyrazoles as Cyclin Dependent Kinase 2 Inhibitors

, 4(4): 313 - 321

Nigus Dessalew and Sanjeev Kumar Singh


DOI: 10.2174/157340608784872244




Involvement of Cysteine Protease Inhibitors in the Defense Mechanism Against Parasites

, 4(4): 322 - 327

Kenji Izuhara, Sachiko Kanaji, Kazuhiko Arima, Shoichiro Ohta and Hiroshi Shiraishi


DOI: 10.2174/157340608784872190




Two-Dimensional QSAR Studies on Arylpiperazines as High-Affinity 5-HT1A Receptor Ligands

, 4(4): 328 - 335

Karen C. Weber, Kathia M. Honorio, Adriano D. Andricopulo and Alberico B. F. Da Silva


DOI: 10.2174/157340608784872325




Hormonal Status Modifies Renin-Angiotensin System-Regulating Aminopeptidases andVasopressin-DegradingActivity in the Hypothalamus-Pituitary-Adrenal Axis of Female Mice

, 4(4): 336 - 347

Maria Jesus Garcia, Jose Manuel Martinez-Martos, Maria Dolores Mayas, Maria Pilar Carrera, Susana De la Chica, Pedro Cortes and Maria Jesus Ramirez-Exposito


DOI: 10.2174/157340608784872271




A Novel Polyarginine Containing Smac Peptide Conjugate that Mediates Cell Death in Tumor and Healthy Cells

, 4(4): 348 - 354

S. Heckl, A. Sturzu, M. Regenbogen, A. Beck, G. Feil, A. Gharabaghi and H. Echner


DOI: 10.2174/157340608784872217




Relationship Between Structure and Antioxidative Properties of Some 3-Formylchromone Derivatives

, 4(4): 355 - 357

F. Sersen, D. Loos, L. Mezesova and M. Lacova


DOI: 10.2174/157340608784872262




Metformin Protects the Brain Against the Oxidative Imbalance Promoted by Type 2 Diabetes

, 4(4): 358 - 364

Sonia Correia, Cristina Carvalho, Maria S. Santos, Teresa Proenca, Elsa Nunes, Ana I. Duarte, Pedro Monteiro, Raquel Seica, Catarina R. Oliveira and Paula I. Moreira


DOI: 10.2174/157340608784872299




Effect of Green Tea on Iron Status and Oxidative Stress in Iron-Loaded Rats

, 4(4): 365 - 370

S. Ounjaijean, C. Thephinlap, U. Khansuwan, C. Phisalapong, S. Fucharoen, J. B. Porter and S. Srichairatanakool


DOI: 10.2174/157340608784872316




New Lanthanide Complexes with Antioxidant Activity

, 4(4): 371 - 378

Irena Kostova, Maria Traykova and Vinod K. Rastogi


DOI: 10.2174/157340608784872181




Truncation of the Krebs Cycle During Hypoglycemic Coma

, 4(4): 379 - 385

Garnette R. Sutherland, Randy L. Tyson and Roland N. Auer


DOI: 10.2174/157340608784872235




Drug Delivery System Based on Responses to an HIV Infectious Signal

, 4(4): 386 - 391

Daisuke Asai, Kota Bae Kodama, Yoko Shoji, Hideki Nakashima, Kenji Kawamura, Jun Oishi, Masanori Kuramoto, Takuro Niidome and Yoshiki Katayama


DOI: 10.2174/157340608784872307




Synthesis, Characterization, and Antimalarial Activity of Novel Schiff-Base-Phenol and Naphthalene-Amine Ligands

, 4(4): 392 - 395

Scott E. Harpstrite, Silvia D. Collins, Ana Oksman, Daniel E. Goldberg and Vijay Sharma


DOI: 10.2174/157340608784872280




Prediction of Cytochrome P450 2B6-Substrate Interactions Using Pharmacophore Ensemble/Support Vector Machine (PhE/SVM) Approach

, 4(4): 396 - 406

Max K. Leong and Tzu-Hsien Chen


DOI: 10.2174/157340608784872226




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