Contents

Medicinal Chemistry, Volume 4 - Number 3

2(3)-Aryl-thio(oxy)-methylquinoxaline Derivatives: A New Class of P-Glycoprotein-Mediated Drug Efflux Inhibitors

, 4(3): 194 - 205

Antonio Carta, Sandra Piras, Giuseppe Paglietti, Sabrina Pricl, Paolo La Colla, Bernardetta Busonera and Roberta Loddo


DOI: 10.2174/157340608784325197




Design, Synthesis, and Preliminary Evaluation of New Pyrrolidine Derivatives as Neuraminidase Inhibitors

, 4(3): 206 - 209

Jie Zhang, Wenfang Xu, Ailin Liu and Guanhua Du


DOI: 10.2174/157340608784325151




CDK9 a Potential Target for Drug Development

, 4(3): 210 - 218

Fernanda Canduri, Patricia Cardoso Peres, Rafael Andrade Caceres and Walter Filgueira de Azevedo Jr.


DOI: 10.2174/157340608784325205




Aqueous Extract of Arbutus unedo Inhibits STAT1 Activation in Human Breast Cancer Cell Line MDA-MB-231 and Human Fibroblasts Through SHP2 Activation

, 4(3): 219 - 228

S. Mariotto, A. R. Ciampa, A. Carcereri de Prati, E. Darra, S. Vincenzi, M. Sega, E. Cavalieri, K. Shoji and H. Suzuki


DOI: 10.2174/157340608784325179




Synthesis, Evaluation and QSAR Studies of 16-(4 & 3,4-Substituted) Benzylidene Androstene Derivatives as Anticancer Agents

, 4(3): 229 - 236

S. Dubey, P. Kaur, D. P. Jindal, Y. D. Satyanarayan and P. Piplani


DOI: 10.2174/157340608784325133




Quantitative Structure – ActivityRelationship (QSAR) of N-Arylsubstituted Hydroxamic Acids as Inhibitors of Human Adenocarinoma Cells A431

, 4(3): 237 - 243

Ram Prakash Rajwade, Rama Pande, K. P. Mishra, Amit Kumar and B. N. Pandey


DOI: 10.2174/157340608784325106




β-Cyclodextrin Conjugates with Glucose Moieties Designed as Drug Carriers: Their Syntheses, Evaluations Using Concanavalin A and Doxorubicin, and Structural Analyses by NMR Spectroscopy

, 4(3): 244 - 255

Yoshiki Oda, Natsumi Kobayashi, Takashi Yamanoi, Kaname Katsuraya, Keiko Takahashi and Kenjiro Hattori


DOI: 10.2174/157340608784325098




Expression of mRNA of Neurotrophic Factors and their Receptors are Significantly Altered After Subchronic Ketamine Treatment

, 4(3): 256 - 263

Axel Becker, Gisela Grecksch, Herbert Schwegler and Thomas Roskoden


DOI: 10.2174/157340608784325124




Live Yeast Cell Derivative Induces c-fos Expression in THP-1 Monocytes

, 4(3): 264 - 272

Andrew Osterburg and Stephen J. Keller


DOI: 10.2174/157340608784325142




Quantitative Structure Activity Analysis of 2-Alkoxydihydrocinnamates as PPARα /γ Dual Agonist

, 4(3): 273 - 277

P. Manoj Kumar, R. Hemalatha, S. C. Mahajan, C. Karthikeyan, N. S. Hari Narayana Moorthy and Piyush Trivedi


DOI: 10.2174/157340608784325188




Shifting the Polarity of some Critical Residues in Malarial Peptides Binding to Host Cells is a Key Factor in Breaking Conserved Antigens Code of Silence

, 4(3): 278 - 292

G. Cifuentes, A. Bermudez, R. Rodriguez, M. A. Patarroyo and M. E. Patarroyo


DOI: 10.2174/157340608784325160




The Effect of Soybean Oil on Glycaemic Control in Goto-Kakizaki Rats,an Animal Model of Type 2 Diabetes

, 4(3): 293 - 297

Cristina M. Sena, Teresa Proenca, Elsa Nunes, Maria S. Santos and Raquel M. Seica


DOI: 10.2174/157340608784325115




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