Contents

Medicinal Chemistry, Volume 4 - Number 2

Synthesis and Cytotoxicity Studies of New Morpholino-Functionalised and N-Heteroaryl-Substituted Titanocene Anticancer Drugs

, 4(2): 91 - 99

M. Tacke, M. Hogan, J. Claffey and C. Pampillon


DOI: 10.2174/157340608783789202




Photoperiod and Testosterone Modulate Growth and Melanogenesis of S91 Murine Melanoma

, 4(2): 100 - 105

Paulo A. A. Allil, Maria A. Visconti, Ana Maria L. Castrucci and Mauro C. Isoldi


DOI: 10.2174/157340608783789185




Cytotoxic and Apoptogenic Activity of a Methanolic Extract from the Marine Invertebrate Ciona intestinalis on Malignant Cell Lines

, 4(2): 106 - 109

Elisabetta Tosti, Gian Luigi Russo, Gaetano Ciarcia, Emilio Presidente and Rosa Anna Siciliano


DOI: 10.2174/157340608783789121




Quantitative Structure-Activity Relationships for Commercially Available Inhibitors of COX-2

, 4(2): 110 - 115

M. Doble and P. M. Sivakumar


DOI: 10.2174/157340608783789112




Inhibitory Feature of the Proprotein Convertases Prosegments

, 4(2): 116 - 120

Abdel-Majid Khatib, Yannick Bontemps, Marion Lapierre, Geraldine Siegfried and Fabien Calvo


DOI: 10.2174/157340608783789176




Synthesis and Pharmacological Profile of a Series of 1-substituted-2-Carbonyl Derivatives of Diphenidol: Novel M4 Muscarinic Receptor Antagonists

, 4(2): 121 - 128

Lucilla Varoli, Piero Angeli, Michela Buccioni, Silvia Burnelli, Nicola Fazio, Gabriella Marucci, Maurizio Recanatini and Santi Spampinato


DOI: 10.2174/157340608783789211




Synthesis and Endothelin Receptor Binding Affinity of a Novel Class of 2-Substituted-4-aryl-3-quinolinecarboxylic Acid Derivatives

, 4(2): 129 - 137

Valeria Pittala, Maria Modica, Loredana Salerno, Maria Angela Siracusa, Francesco Guerrera, Ilario Mereghetti, Alfredo Cagnotto, Tiziana Mennini and Giuseppe Romeo


DOI: 10.2174/157340608783789095




Comparative Antiviral (HIV) Photoactivity of Metalized meso-Tetraphenylsulfonated Porphyrins

, 4(2): 138 - 145

Franklin Vargas, Carlos Rivas, Tamara Zoltan, Liliana Padron, Carla Izzo, Veronica Lopez, Lubimar Gomez, Flor Pujol, Hector Rangel, Domingo Garzaro and Rona Fabbro


DOI: 10.2174/157340608783789167




Synthesis of Some Thiophene, Imidazole and Pyridine Derivatives Exhibiting Good Anti-Inflammatory and Analgesic Activities

, 4(2): 146 - 154

Sham M. Sondhi, Shubhi Jain, Monica Dinodia and Ashok Kumar


DOI: 10.2174/157340608783789194




Photoreactive DNA Probes as a Tool for Studying the Translesion Synthesis System in Mammalian Cell Extracts

, 4(2): 155 - 162

Olga I. Lavrik, Ekaterina A. Belousova, Emmanuele Crespan, Natalia A. Lebedeva, Nadejda I. Rechkunova, Ulrich Hubscher and Giovanni Maga


DOI: 10.2174/157340608783789158




In Vitro Leishmanicidal Activity of 3-substituted Isocoumarins: Synthesis and Structure activity Relationship

, 4(2): 163 - 169

Khalid Mohammed Khan, Sumbul Ahmed, Zulfiqar Ali Khan, Zia-Ullah, Mubeen Rani, Muhammad Iqbal Choudhary and Shahnaz Perveen


DOI: 10.2174/157340608783789130




Prediction of Distribution of Neutral, Acidic and Basic Structurally Diverse Compounds Between Blood and Brain by the Nonlinear Methodology

, 4(2): 170 - 189

Huabei Zhang, Shaoping Hu and Yaling Zhang


DOI: 10.2174/157340608783789103




Anti-Tubercular and Anti-Inflammatory Activities of Azetidin-2-One Derivatives and Their Effects on the Activity of Phospholipase A2

, 4(2): 190 - 193

Mayur C. Yerigeri, Satish Kumar Murari, Kuntebommanahalli N. Thimmaiah, Shanta Kumar Sugur Math and Bannikuppe Sannanaik Vishwanath


DOI: 10.2174/157340608783789149




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