Contents

Medicinal Chemistry, Volume 3 - Number 2

Antileishmanial and Antimalarial Chalcones: Synthesis, Efficacy and Cytotoxicity of Pyridinyl and Naphthalenyl Analogs

, 3(2): 115 - 119

C. E. Gutteridge, J. V. Vo, C. B. Tillett, J. A. Vigilante, J. R. Dettmer, S. L. Patterson, K. A. Werbovetz, J. Capers, D. A. Nichols, A. K. Bhattacharjee and L. Gerena


DOI: 10.2174/157340607780059530




Evaluation of Polygonum bistorta for Anticancer Potential Using Selected Cancer Cell Lines

, 3(2): 121 - 126

Karuppiah Pillai Manoharan, Daiwen Yang, Annie Hsu and Benny Tan Kwong Huat


DOI: 10.2174/157340607780059495




2-Amino/Azido/Hydrazino-5-alkoxy-5H-[1]benzopyrano[4,3-d]pyrimidines:Synthesis and Pharmacological Evaluation

, 3(2): 127 - 134

O. Bruno, C. Brullo, F. Bondavalli, A. Ranise, S. Schenone, M. Tognolini, V. Ballabeni and E. Barocelli


DOI: 10.2174/157340607780059549




Flexible Estrogen Receptor Modulators: Synthesis, Biochemistry and Molecular Modeling Studies for 3-Benzyl-4,6-diarylhex-3-ene and 3,4,6-Triarylhex-3-ene Derivatives

, 3(2): 135 - 155

Helena M. Smith, Andrew J. S. Knox, Daniela M. Zisterer, David G. Lloyd and Mary J. Meegan


DOI: 10.2174/157340607780059503




Cellular Pharmacology, Antineoplastic Activity and Low In Vivo Toxicity of a Carboxylato-Bridged Platinum(II) Complex bis(acetato)diammine-bis-μ-acetato diplatinum (II) Dihydrate

, 3(2): 157 - 165

Georgi Momekov, Spiro Konstantinov, Margarita Topashka-Ancheva, Adriana Bakalova, Sonja Arpadjan and Margarita Karaivanova


DOI: 10.2174/157340607780059486




A Quantitative Structure-Activity Relationship Study on Some Novel Series of Hydroxamic Acid Analogs Acting as Matrix Metalloproteinase Inhibitors

, 3(2): 167 - 173

S. Kumaran and S. P. Gupta


DOI: 10.2174/157340607780059477




Synthesis of Phenyl-substituted Amides with Antioxidant and Antiinflammatory activity as Novel Lipoxygenase Inhibitors

, 3(2): 175 - 186

E. Pontiki and D. Hadjipavlou-Litina


DOI: 10.2174/157340607780059512




Pharmacophore Modeling in Drug Discovery and Development: An Overview

, 3(2): 187 - 197

Santosh A. Khedkar, Alpeshkumar K. Malde, Evans C. Coutinho and Sudha Srivastava


DOI: 10.2174/157340607780059521




Control of HIV Through the Inhibition of HIV-1 Integrase: A Medicinal Chemistry Perspective

, 3(2): 199 - 220

C. P. Gordon, R. Griffith and P. A. Keller


DOI: 10.2174/157340607780059558




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