Contents

Medicinal Chemistry, Volume 2 - Number 3

Inhibitory Effects of Bisphosphonates on the Proliferation of Human Ovarian Cancer Cell Lines and the Mechanism

, 2(3): 223 - 226

Hiroshi Seto, Tsunekazu Kita, Junko Hirata, Yoshihiro Kikuchi and Kazuya Kudoh


DOI: 10.2174/157340606776930727




Cellular Sensitivity to β-Diketonato Complexes of Ruthenium(III), Chromium(III) and Rhodium(III)

, 2(3): 227 - 237

S. Radulovic, P. Apostoli, R. Leone, F. Zunino, P. Perego, L. Gatti, N. Carenini, Z. Tesic and S. Arandjelovic


DOI: 10.2174/157340606776930718




Discovery of Potential Sorbitol Dehydrogenase Inhibitors from Virtual Screening

, 2(3): 239 - 242

Ossama El-Kabbani, Deborah A. Carper, Takeshi Iwata and Connie Darmanin


DOI: 10.2174/157340606776930772




Quantitative Structure-Activity Relationship Studies on Matrix Metalloproteinase Inhibitors: Hydroxamic Acid Analogs

, 2(3): 243 - 250

S. P. Gupta and S. Kumaran


DOI: 10.2174/157340606776930790




Antioxidant and Anti-Inflammatory Activity of Aryl-Acetic and Hydroxamic Acids as Novel Lipoxygenase Inhibitors

, 2(3): 251 - 264

E. Pontiki and D. Hadjipavlou-Litina


DOI: 10.2174/157340606776930763




Pigment Epithelium-Derived Factor (PEDF) Blocks Angiotensin IIInduced T Cell Proliferation by Suppressing Autocrine Production of Interleukin-2

, 2(3): 265 - 269

Hiroyoshi Inoue, Masayoshi Takeuchi, Takanori Matsui, Sho-ichi Yamagishi, Seiji Kikuchi and Kazuo Nakamura


DOI: 10.2174/157340606776930826




Heme Arginate Pretreatment Attenuates Pulmonary NF-κB and AP-1 Activation Induced by Hemorrhagic Shock via Heme Oxygenase-1 Induction

, 2(3): 272 - 274

M. Yokoyama, R. Akagi, K. Morita, M. Takeuchi, H. Morimatsu, Y. Toda, H. Shimizu, K. Maeshima, T. Sasaki and T. Takahashi


DOI: 10.2174/157340606776930781




Induction of Quinone Reductase NQO1 by Resveratrol in Human K562 Cells Involves the Antioxidant Response Element ARE and is Accompanied by Nuclear Translocation of Transcription Factor Nrf2

, 2(3): 275 - 285

Joseph M. Wu, Tze-chen Hsieh, Xiaohua Lu and Zhirong Wang


DOI: 10.2174/157340606776930709




In vitro Anti-Mycobacterial Activities of Various 2-Deoxyuridine, 2- Arabinouridine and 2-Arabinofluoro-2-deoxyuridine Analogues: Synthesis and Biological Studies

, 2(3): 287 - 293

Rakesh Kumar, Dennis Y. Kunimoto, Tracey Manning and Naveen C. Srivastav


DOI: 10.2174/157340606776930745




Novel Fibrinogen Receptor Antagonists - RGDF Mimetics, 4-(1,2,3,4- tetrahydro-isoquinoline-7-yl)amino-4-oxo-butyric Acid Derivatives

, 2(3): 295 - 298

Sergei A. Andronati, Olga L. Malovichko, Andrei A. Krysko, Tatyana A. Kabanova, Tamara L. Karaseva and Anna S. Petrus


DOI: 10.2174/157340606776930817




Insulin Attenuates Diabetes-Related Mitochondrial Alterations: A Comparative Study

, 2(3): 299 - 308

P. I. Moreira, A. P. Rolo, C. Sena, R. Seica, C. R. Oliveira and M. S. Santos


DOI: 10.2174/157340606776930754




Molecular Modeling Studies of Peptide Drug Candidates against SARS

, 2(3): 309 - 314

Rui Zhang, Dong-Qing Wei, Qi-Shi Du and Kuo-Chen Chou


DOI: 10.2174/157340606776930736




Development of Hypoxia Selective Cytotoxins for Cancer Treatment: An Update

, 2(3): 315 - 327

Hugo Cerecetto, Mercedes Gonzalez and Maria L. Lavaggi


DOI: 10.2174/157340606776930808




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