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Medicinal Chemistry

Volume 17, 10 Issues, 2021
ISSN: 1875-6638 (Online)
ISSN: 1573-4064 (Print)
This journal supports open access


Medicinal Chemistry, Volume 14 - Number 5

Review Article

Emerging Roles of Purinergic Signaling in Diabetes

, 14(5): 428 - 438

Carmen Fotino, Diego Dal Ben and Elena Adinolfi*

DOI: 10.2174/1573406414666180226165204

Research Article

Towards the In-silico Design of New HSP90 Inhibitors: Molecular Docking and 3D-QSAR CoMFA Studies of Tetrahydropyrido [4, 3-d] Pyrimidine Derivatives as HSP90 Inhibitors

, 14(5): 439 - 450

Bakhtyar Sepehri and Raouf Ghavami*

DOI: 10.2174/1573406414666180321151029

Research Article

Facile Synthesis, Crystal Structure, DFT Calculation and Biological Activities of 4-(2-fluorophenyl)-3-(3-methoxybenzyl)-1H-1,2,4-triazol-5 (4H)-one (5)

, 14(5): 451 - 459

Muhammad Saleem, Muhammad Rafiq, Yeon Ki Jeong, Dae Won Cho, Chong-Hyeak Kim, Sung-Yum Seo, Chang-Shik Choi, Seong-Karp Hong and Ki-Hwan Lee*

DOI: 10.2174/1573406414666180112122856

Research Article

Activity of Diosgenyl 2-amino-2-deoxy- -D-glucopyranoside, its Hydrochloride, and N,N-dialkyl Derivatives Against Non-albicans Candida Isolates

, 14(5): 460 - 467

Malgorzata Anna Dawgul*, Daria Grzywacz, Beata Liberek, Wojciech Kamysz and Henryk Myszka

DOI: 10.2174/1573406414666180226164747

Research Article

Synthesis and Structure-Activity Relationship; Exploration of some Potent Anti-Cancer Phenyl Amidrazone Derivatives

, 14(5): 468 - 477

Almeqdad Y. Habashneh, Mustafa M. El-Abadelah, Sanaa K Bardaweel and Mutasem O. Taha*

DOI: 10.2174/1573406414666171204143157

Research Article

Scaffold Hopping Strategy for the Design, Synthesis and Biological Activity Evaluation of Novel Hexacyclic Scutellarein Derivatives with a 1,3-Oxazine Ring Fused at A-ring

, 14(5): 478 - 484

Yue Zhong , Yu-Ting Lu, Ying Sun, Nian-Guang Li, Ting Gu, Wen-Yu Wu, Shao-Peng Yu and Zhi-Hao Shi *

DOI: 10.2174/1573406413666170906130251

Research Article

Design and Synthesis of 3,4-diarylpyrrole Analogues as Potent Topoisomerase Inhibitors

, 14(5): 485 - 494

Wang Chen*, Zili Feng, Xu He, Qiang Zhao and Qi Liang

DOI: 10.2174/1573406414666180226164049

Research Article

Prodrugs for Nitroreductase Based Cancer Therapy- 1: Metabolite Profile, Cell Cytotoxicity and Molecular Modeling Interactions of Nitro Benzamides with Ssap-NtrB

, 14(5): 495 - 507

Tugba Gungor, Gulden Yetis, Ferah C. Onder, Esra Tokay, Tugba T. Tok, Ayhan Celik, Mehmet Ay* and Feray Kockar

DOI: 10.2174/1573406413666171129224424

Research Article

Inhibition of Adipogenesis by Thiourea Derivatives

, 14(5): 508 - 515

Hina Siddiqui*, Sarah Shafi, Farah Mukhtar, Asma Ejaz, Atta ur-Rahman and M. Iqbal Choudhary*

DOI: 10.2174/1573406413666171120161208

Research Article

Anthranilic Acid Derivatives: Novel Inhibitors of Protein Glycation and the Associated Oxidative Stress in the Hepatocytes

, 14(5): 516 - 523

Humera Jahan*, Muhammad Iqbal Choudhary, Amber Atta, Khalid M. Khan and Atta- ur-Rahman

DOI: 10.2174/1573406413666171020120528

Research Article

Xanthine Oxidase Inhibitory and Molecular Docking Studies on Pyrimidones

, 14(5): 524 - 535

Humaira Zafar, Sarosh Iqbal, Sumaira Javaid, Khalid M. Khan* and Muhammad I. Choudhary*

DOI: 10.2174/1573406413666171129224919

Research Article

New Bis-Pyrazolones as Potential Leads for ROS Inhibition; Environment Friendly Green Synthesis, Structural Characterization, and In Vitro Studies

, 14(5): 536 - 548

Sahar Yousuf*, Khalid M. Khan, Uzma Salar, Almas Jabeen, Shakil Ahmed, Munira T. Muhammad, Aisha Faheem and Shahnaz Perveen

DOI: 10.2174/1573406414666180112122001


Dimitra Hadjipavlou-Litina
Department of Pharmaceutical Chemistry, School of Pharmacy
Aristotle University of Thessaloniki
View Full Editorial Board

Nobel Laureate on Editorial Board

Prof. Ferid Murad

COPE Compliant

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Journal History

Medicinal Chemistry Journal was launched in 2005. Dr. Dimitra Hadjipavlou-Litina serves as the Editor-in-Chief of the journal.

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