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Medicinal Chemistry

Volume 15, 8 Issues, 2019
ISSN: 1875-6638 (Online)
ISSN: 1573-4064 (Print)
This journal supports open access

Contents

Medicinal Chemistry, Volume 14 - Number 4


Research Article

The Synthesis of Chalcones as Anticancer Prodrugs and their Bioactivation in CYP1 Expressing Breast Cancer Cells

, 14(4): 322 - 332

Ketan C. Ruparelia*, Keti Zeka, Taeeba Ijaz, Dyan N. Ankrett, Nicola E. Wilsher, Paul C. Butler, Hoon L. Tan, Sabahat Lodhi, Avninder S. Bhambra, Gerard A. Potter, Randolph R.J. Arroo and Kenneth J.M. Beresford


DOI: 10.2174/1573406414666180112120134



Research Article

Design, Synthesis, and Evaluation of (2-(Pyridinyl)methylene)-1-tetralone Chalcones for Anticancer and Antimicrobial Activity

, 14(4): 333 - 343

Maya Z. Gibson, Minh A. Nguyen and Sarah K. Zingales*


DOI: 10.2174/1573406413666171020121244



Research Article

Synthesis, Cytotoxicity Evaluation, Molecular Docking and Utility of Novel Chalcones as Precursors for Heterocycles Incorporating Pyrazole Moiety

, 14(4): 344 - 355

Sobhi M. Gomha*, Magda A. Abdallah, Ikhlass M. Abbas and Mariam S.H. Kazem


DOI: 10.2174/1573406413666171020114105



Research Article

Synthesis of New Isoxazole-, Pyridazine-, Pyrimidopyrazines and Their Anti-Inflammatory and Analgesic Activity

, 14(4): 356 - 371

Ameen A. Abu-Hashem* and Mohamed El-Shazly


DOI: 10.2174/1573406414666180112110947



Research Article

Synthesis and in vitro Antioxidant Activity Study of Some Novel Substituted Piperazinyl Flavone Compounds

, 14(4): 372 - 386

Elmas Sari, Pawel Berczynski, Aleksandra Kladna, Irena Kruk, Oya Bozdag Dundar, Monika Szymanska and Hassan Y. Aboul-Enein*


DOI: 10.2174/1573406414666171204105000



Research Article

A Novel Method to Synthesize Phosphocreatine and Phosphocreatine Prodrugs

, 14(4): 387 - 393

Maria Arkel, Patrizia Garbati, Annalisa Salis, Gianluca Damonte, Nara Liessi, Enrico Adriano, Umberto Benatti, Maurizio Balestrino and Enrico Millo*


DOI: 10.2174/1573406413666171120164702



Research Article

Activity of Rifabutin and Hemi-synthetic Derivatives Against Mycobacterium abscessus

, 14(4): 394 - 399

Ivy B. Ramis*, Ricardo Figueiredo, Daniela F. Ramos, Priscila C.B. Halicki, Andrea von Groll, Miguel Viveiros, Maria do Ceu Costa and Pedro E.A. da Silva


DOI: 10.2174/1573406414666171204102633



Research Article

Efficient One-Pot Access to Trisubstituted 2-Benzazepin-3-ones as Constrained Pseudopeptide Analogues and Privileged Scaffolds

, 14(4): 400 - 408

Olivier Van der Poorten, Mouhamad Jida*, Dirk Tourwe and Steven Ballet*


DOI: 10.2174/1573406413666171002122233



Research Article

Design, Synthesis, Evaluation and Computational Studies of Nipecotic Acid-Acetonaphthone Hybrids as Potential Antiepileptic Agents

, 14(4): 409 - 426

Ankit Seth, Piyoosh A. Sharma, Avanish Tripathi, Priyanka K. Choubey, Pavan Srivastava, Prabhash N. Tripathi and Sushant K. Shrivastava*


DOI: 10.2174/1573406414666180116104225





Editor-in-Chief

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

Biography View Full Editorial Board

Journal History

Medicinal Chemistry Journal was launched in 2005. Dr. Dimitra Hadjipavlou-Litina serves as the Editor-in-Chief of the journal.
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