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Medicinal Chemistry

Volume 17, 10 Issues, 2021
ISSN: 1875-6638 (Online)
ISSN: 1573-4064 (Print)
This journal supports open access


Medicinal Chemistry, Volume 14 - Number 4

Research Article

The Synthesis of Chalcones as Anticancer Prodrugs and their Bioactivation in CYP1 Expressing Breast Cancer Cells

, 14(4): 322 - 332

Ketan C. Ruparelia*, Keti Zeka, Taeeba Ijaz, Dyan N. Ankrett, Nicola E. Wilsher, Paul C. Butler, Hoon L. Tan, Sabahat Lodhi, Avninder S. Bhambra, Gerard A. Potter, Randolph R.J. Arroo and Kenneth J.M. Beresford

DOI: 10.2174/1573406414666180112120134

Research Article

Design, Synthesis, and Evaluation of (2-(Pyridinyl)methylene)-1-tetralone Chalcones for Anticancer and Antimicrobial Activity

, 14(4): 333 - 343

Maya Z. Gibson, Minh A. Nguyen and Sarah K. Zingales*

DOI: 10.2174/1573406413666171020121244

Research Article

Synthesis, Cytotoxicity Evaluation, Molecular Docking and Utility of Novel Chalcones as Precursors for Heterocycles Incorporating Pyrazole Moiety

, 14(4): 344 - 355

Sobhi M. Gomha*, Magda A. Abdallah, Ikhlass M. Abbas and Mariam S.H. Kazem

DOI: 10.2174/1573406413666171020114105

Research Article

Synthesis of New Isoxazole-, Pyridazine-, Pyrimidopyrazines and Their Anti-Inflammatory and Analgesic Activity

, 14(4): 356 - 371

Ameen A. Abu-Hashem* and Mohamed El-Shazly

DOI: 10.2174/1573406414666180112110947

Research Article

Synthesis and in vitro Antioxidant Activity Study of Some Novel Substituted Piperazinyl Flavone Compounds

, 14(4): 372 - 386

Elmas Sari, Pawel Berczynski, Aleksandra Kladna, Irena Kruk, Oya Bozdag Dundar, Monika Szymanska and Hassan Y. Aboul-Enein*

DOI: 10.2174/1573406414666171204105000

Research Article

A Novel Method to Synthesize Phosphocreatine and Phosphocreatine Prodrugs

, 14(4): 387 - 393

Maria Arkel, Patrizia Garbati, Annalisa Salis, Gianluca Damonte, Nara Liessi, Enrico Adriano, Umberto Benatti, Maurizio Balestrino and Enrico Millo*

DOI: 10.2174/1573406413666171120164702

Research Article

Activity of Rifabutin and Hemi-synthetic Derivatives Against Mycobacterium abscessus

, 14(4): 394 - 399

Ivy B. Ramis*, Ricardo Figueiredo, Daniela F. Ramos, Priscila C.B. Halicki, Andrea von Groll, Miguel Viveiros, Maria do Ceu Costa and Pedro E.A. da Silva

DOI: 10.2174/1573406414666171204102633

Research Article

Efficient One-Pot Access to Trisubstituted 2-Benzazepin-3-ones as Constrained Pseudopeptide Analogues and Privileged Scaffolds

, 14(4): 400 - 408

Olivier Van der Poorten, Mouhamad Jida*, Dirk Tourwe and Steven Ballet*

DOI: 10.2174/1573406413666171002122233

Research Article

Design, Synthesis, Evaluation and Computational Studies of Nipecotic Acid-Acetonaphthone Hybrids as Potential Antiepileptic Agents

, 14(4): 409 - 426

Ankit Seth, Piyoosh A. Sharma, Avanish Tripathi, Priyanka K. Choubey, Pavan Srivastava, Prabhash N. Tripathi and Sushant K. Shrivastava*

DOI: 10.2174/1573406414666180116104225


Dimitra Hadjipavlou-Litina
Department of Pharmaceutical Chemistry, School of Pharmacy
Aristotle University of Thessaloniki
View Full Editorial Board

Nobel Laureate on Editorial Board

Prof. Ferid Murad

COPE Compliant

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Journal History

Medicinal Chemistry Journal was launched in 2005. Dr. Dimitra Hadjipavlou-Litina serves as the Editor-in-Chief of the journal.

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