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Contents

Medicinal Chemistry, Volume 13 - Number 8


Review Article

The Role of QSAR and Virtual Screening Studies in Type 2 Diabetes Drug Discovery

, 13(8): 706 - 720

Simone Q. Pantaleao, Drielli G.V. Fujii, Vinicius G. Maltarollo, Danielle da C. Silva, Gustavo H.G. Trossini, Karen C. Weber, Luis P.B. Scott and Kathia M. Honorio*


DOI: 10.2174/1573406413666170522152102



Research Article

Isolation of Chlorogenic Acid from Soil Borne Fungi Screlotium rolfsii, their Reversal of Multidrug Resistance and Anti-proliferative in Mouse Lymphoma Cells

, 13(8): 721 - 726

Bashir Ahmad, Muhammad Rizwan, Abdur Rauf *, Muslim Raza, Shumaila Bashir , Joseph Molnar, Akos Csonka, Diana Szabo, Mohammad S. Mubarak, Mah Noor and Bina S. Siddiqui


DOI: 10.2174/1573406413666170612110443



Research Article

IRS-1 pY612 and Akt-1/PKB pT308 Phosphorylation and Antiinflammatory Effect of Diindolylmethane in Adipocytes Cocultured with Macrophages

, 13(8): 727 - 733

Alfonso Lopez-Vazquez, Jesus J. Garcia-Banuelos*, Angelica S. Gonzalez-Garibay, Pedro E. Urzua-Lozano, Susana Del Toro-Arreola, Miriam R. Bueno-Topete, Sergio Sanchez-Enriquez, Jose F. Munoz-Valle, Luis F. Jave-Suarez, Juan Armendariz-Borunda and Blanca E. Bastidas-Ramirez*


DOI: 10.2174/1573406413666170922095011



Research Article

iRNA-2methyl: Identify RNA 2'-O-methylation Sites by Incorporating Sequence-Coupled Effects into General PseKNC and Ensemble Classifier

, 13(8): 734 - 743

Wang-Ren Qiu*, Shi-Yu Jiang , Bi-Qian Sun, Xuan Xiao*, Xiang Cheng and Kuo-Chen Chou*


DOI: 10.2174/1573406413666170623082245



Research Article

Synthesis of New Arylidene 2,5-Diketopiperazines and Evaluation of their Anti-Acetylcholinesterase, Anti-xanthine Oxidase, Anti-diabetic and Cytotoxic Activities

, 13(8): 744 - 752

Mohamed A. Belkacem, Hichem B. Jannet*, Hicham Ferhout, Laila Mzali and Jalloul Bouajila*


DOI: 10.2174/1573406413666170425165659



Research Article

Design, Synthesis, and Biological Evaluation of C-2 Substituted 3Hthieno[ 2,3-d]pyrimidin-4-one Derivatives as Novel FGFR1 Inhibitors

, 13(8): 753 - 760

Ping Guo, Zixin Xie, Huan Zhang, Zaikui Zhang , Chao Han , Donghua Cheng, Dan Lin, Yuan Zhang, Xuebao Wang, Xin Guo and Faqing Ye *


DOI: 10.2174/1573406413666170623084525



Research Article

Synthesis and Biological Evaluation of Curcumin-Nitroxide-Based Molecular Hybrids as Antioxidant and Anti-Proliferative Agents

, 13(8): 761 - 772

Balazs Bognar, M. Lakshmi Kuppusamy, Esha Madan, Tamas Kalai, Maria Balog, Jozsef Jeko, Periannan Kuppusamy and Kalman Hideg*


DOI: 10.2174/1871520617666170522124712



Research Article

Synthesis and Analgesic Activity of Amines Combining Diazaadamantane and Monoterpene Fragments

, 13(8): 773 - 779

Konstantin Ponomarev, Ekaterina Morozova, Alla Pavlova, Evgeniy Suslov*, Dina Korchagina, Andrej Nefedov, Tat'yana Tolstikova, Konstantin Volcho and Nariman Salakhutdinov


DOI: 10.2174/1573406413666170525124316



Research Article

Synthesis, Structural Characterization and Antinociceptive Activities of New Arylated Quinolines via Suzuki-Miyaura Cross Coupling Reaction

, 13(8): 780 - 786

Malik A. Ullah, Muhammad Adeel, Muhammad N. Tahir, Abdur Rauf*, Muhammad Akram, Taibi B. Hadda, Yahia N. Mabkhot, Naveed Muhammad, Fehmida Naseer and Mohammad S. Mubarak*


DOI: 10.2174/1573406413666170704100611



Research Article

Identification of Novel 5,6-Dimethoxyindan-1-one Derivatives as Antiviral Agents

, 13(8): 787 - 795

Siddappa A. Patil*, Vikrant Patil, Renukadevi Patil, Kenneth Beaman and Shivaputra A. Patil*


DOI: 10.2174/1573406413666170330094822



Research Article

Better Predictive Value of Cancer Antigen125 (CA125) as Biomarker in Ovary and Breast Tumors and its Correlation with the Histopathological Type/Grade of the Disease

, 13(8): 796 - 804

Aarifa Nazmeen, Smarajit Maiti*, Kusumita Mandal, Samir K. Roy, Tamal K. Ghosh, Nirmalya K. Sinha and Kamalika Mandal


DOI: 10.2174/1573406413666170424155452





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