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Contents

Medicinal Chemistry, Volume 11 - Number 6


Synthesis and Evaluation of Anticancer Activity of 5-Ylidene-4- Aminothiazol-2(5H)-one Derivatives

, 11(6): 517 - 530

Danylo Kaminskyy, Ivanna Subtel’na, Borys Zimenkovsky, Olexandr Karpenko, Andrzej Gzella and Roman Lesyk


DOI: 10.2174/1573406411666150211112049



New Testosterone Derivatives as Semi-Synthetic Anticancer Agents Against Prostate Cancer: Synthesis and Preliminary Biological Evaluation

, 11(6): 531 - 539

Nathalie Morin, Julie Bruneau, Sebastien Fortin, Kevin Brasseur, Valerie Leblanc, Eric Asselin and Gervais Berube


DOI: 10.2174/1573406411666150212120628



Effects of Novel Alkyl Pyridine Platinum Complexes on Apoptosis in Ishikawa Endometrial Cancer Cells

, 11(6): 540 - 550

Robert Czarnomysy, Anna Bielawska, Anna Muszyńska and Krzysztof Bielawski


DOI: 10.2174/1573406411666150206163547



Association of EGF rs4444903 and XPD rs13181 Polymorphisms with Cutaneous Melanoma in Caucasians

, 11(6): 551 - 559

Jun Liu, Jia Song, Mei-Yan Wang, Lin He, Lei Cai and Kuo-Chen Chou


DOI: 10.2174/1573406410666141224115516



Inhibition of NF-kB Activation and Cytokines Production in THP-1 Monocytes by 2-Styrylchromones

, 11(6): 560 - 566

Ana Gomes, João P. Capela, Daniela Ribeiro, Marisa Freitas, Artur M.S. Silva, Diana C.G.A. Pinto, Clementina M.M. Santos, José A.S. Cavaleiro, José L.F.C. Lima and Eduarda Fernandes


DOI: 10.2174/1573406411666150209114702



Synthesis and Biological Evaluation of Acetylenic Chalcones as Novel Anti-Inflammatory Agents

, 11(6): 567 - 572

Chengguang Zhao, Jianpeng Feng, Mingming Zuo, Ying Zhang, Jianfeng Zhao, Shanmei Xu, Suqing Zheng, Yali Zhang, Qinqin Tang, Zhongqiu Lu, Guang Liang and Jianmin Zhou


DOI: 10.2174/1573406411666150209122749



Theoretical Analysis of the Binding of Potential Inhibitors to Protein Kinases MK2 and MK3

, 11(6): 573 - 579

Pedro M.M. Araújo, Luís Pinto da Silva and Joaquim C.G. Esteves da Silva


DOI: 10.2174/1573406411666150209114952



Quinolinyl-Thienyl Chalcones as Monoamine Oxidase Inhibitors and their In Silico Modeling Studies

, 11(6): 580 - 589

Sumera Zaib, Syed Umar Farooq Rizvi, Sana Aslam, Matloob Ahmad, Syed Mobasher Ali Abid, Mariya al-Rashida and Jamshed Iqbal


DOI: 10.2174/1573406410666141226131252



Diagnostic Recognition of Escherichia coli Septicemia in In Vivo Vascular Blood

, 11(6): 590 - 594

Dal Woong Choi and Suw Young Ly


DOI: 10.2174/1573406411666141208152436



Design, Synthesis of 6-Substituted-pyrido[3,2-d]pyridazine Derivatives with Anticonvulsant Activity

, 11(6): 595 - 601

Zheng-Qi Dong, Xiao-Mei Liu, Cheng-Xi Wei and Zhe-Shan Quan


DOI: 10.2174/1573406411666150313152925



N-substituted Pyrrole-based Scaffolds as Potential Anticancer and Antiviral Lead Structures

, 11(6): 602 - 608

Kyriaki Pegklidou, Nikolaos Papastavrou, Petros Gkizis, Dimitrios Komiotis, Jan Balzarini and Ioannis Nicolaou


DOI: 10.2174/1573406411666150313161225




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