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Contents

Medicinal Chemistry, Volume 11 - Number 4



Design of SGLT2 Inhibitors for the Treatment of Type 2 Diabetes: A History Driven by Biology to Chemistry

, 11(4): 317 - 328

Wenqing Cai, Linlin Jiang, Yafei Xie, Yuqiang Liu, Wei Liu and Guilong Zhao


DOI: 10.2174/1573406411666150105105529



Discovery of 9,10-Dihydroacridines as Novel Class of ABCB1 Inhibitors

, 11(4): 329 - 335

Andreas Hilgeroth, Marc Hemmer, Sebastian Neuber, Josef Molnar and Hermann Lage


DOI: 10.2174/1573406410666141111100720



Synthesis and Biological Potential Assessment of 2-Substituted Quinazolin-4(3H)-ones as Inhibitors of Phosphodiesterase-I and Carbonic Anhydrase-II

, 11(4): 336 - 341

Syed Muhammad Saad, Muhammad Saleem, Shahnaz Perveen, Muhammad Tanveer Alam, Khalid Mohammed Khan and Muhammad Iqbal Choudhary


DOI: 10.2174/1573406410666141203123926



Synthesis and Biological Evaluation of Pyrazolo[3,4-b]pyridin-4-ones as a New Class of Topoisomerase II Inhibitors

, 11(4): 342 - 353

Mojgan Aghazadeh Tabrizi, Pier Giovanni Baraldi, Stefania Baraldi, Filippo Prencipe, Delia Preti, Giulia Saponaro, Romeo Romagnoli, Stefania Gessi, Stefania Merighi, Angela Stefanelli, Debora Fazzi, Pier Andrea Borea, Rodolfo Couto Maia, Nelilma C. Romeiro, Carlos A. M. Fraga and Eliezer J. Barreiro


DOI: 10.2174/1573406411666141210141317



Fluorescent Porphyrin with an Increased Uptake in Peripheral Blood Cell Subpopulations from Colon Cancer Patients

, 11(4): 354 - 363

Carolina Constantin and Monica Neagu


DOI: 10.2174/1573406411666141209095837



New Benzimidazole-Derived Isothioureas as Potential Antileukemic Agents - Studies In Vitro

, 11(4): 364 - 372

Miroslawa Koronkiewicz, Anna Romiszewska, Zdzislaw Chilmonczyk and Zygmunt Kazimierczuk


DOI: 10.2174/1573406410666141203124329



Antiproliferative Effect of Novel Aminoacridine-based Compounds

, 11(4): 373 - 382

Anna Munder, Yoni Moskovitz, Boris Redko, Ariel Rachel Levy, Sharon Ruthstein, Gary Gellerman and Arie Gruzman


DOI: 10.2174/1573406411666141217110946



Practical Application of Antidiabetic Efficacy of Lycium barbarum Polysaccharide in Patients with Type 2 Diabetes

, 11(4): 383 - 390

Huizhen Cai, Fukang Liu, Pingguo Zuo, Guiling Huang, Zhixiu Song, Tingting Wang, Huixia Lu, Fei Guo, Chao Han and Guiju Sun


DOI: 10.2174/1573406410666141110153858



Long Term Stability Evaluation of Prostacyclin Released from Biomedical Device through Turbiscan Lab Expert

, 11(4): 391 - 399

Christian Celia, Marcello Locatelli, Felisa Cilurzo, Donato Cosco, Emanuela Gentile, Daniela Scalise, Maria Carafa, Cinzia Anna Ventura, Mathias Fleury, Christelle Tisserand, Renato. C Barbacane, Massimo Fresta, Luisa Di Marzio and Donatella Paolino


DOI: 10.2174/1573406410666141110153502



Identification of Imidazoquinoline Derivatives as Potent Antiglioma Agents

, 11(4): 400 - 406

Shivaputra A. Patil, Susan R. Pfeffer, William L. Seibel, Lawrence M. Pfeffer and Duane D. Miller


DOI: 10.2174/1573406410666140914162701



Design, Synthesis and Antimicrobial Evaluation of Methyl Pyridyl-2,4- Dioxobutanoates and Some New Derived Ring Systems

, 11(4): 407 - 414

Perihan A.S. Elzahhar, Raafat Soliman, Soad A.M. El-Hawash, Hanan M.A. Ragab, Amal M. Youssef and Abeer E. Abdel Wahab


DOI: 10.2174/1573406411666141205102544




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