Contents

Medicinal Chemistry, Volume 10 - Number 8

Synthesis and In Vitro Evaluation of Tropane Halogenated-derivatives Against Malaria, Sleeping Sickness, Chagas Disease and Leishmaniasis

, 10(8): 753 - 758

Sylvian Cretton, Trixie A. Bartholomeusz, Florence Mehl, Yves Allenbach, An Matheeussen, Paul Cos, Louis Maes and Philippe Christen


DOI: 10.2174/1573406410666140507095430



Novel Selenosemicarbazone Metal Complexes Exert Anti-tumor Effect via Alternative, Caspase-independent Necroptotic Cell Death

, 10(8): 759 - 771

Manja Zec, Tatjana Srdic-Rajic, Ana Krivokuca, Radmila Jankovic, Tamara Todorovic, Katarina Andelkovic and Sinisa Radulovic


DOI: 10.2174/1573406410666140327122009



Synthesis and Biological Activity of Anthrapyrazoles Derivatives as Potential Antitumor Agents

, 10(8): 772 - 777

Jianhong Wang, Huijun Zhao, Zhaoyang Luo, Zhaoyi Wang, Yahong Zhang and Jin Zhao


DOI: 10.2174/1573406410666140428152227



β-Glucuronidase Inhibitory Studies on Coumarin Derivatives

, 10(8): 778 - 782

Khalid Mohammed Khan, Muhammad Imran Fakhri, Nimra Naveed Shaikh, Syed Muhammad Saad, Shafqat Hussain, Shahnaz Perveen and Muhammad Iqbal Choudhary


DOI: 10.2174/1573406410666140311093352



Apolipoprotein E Gene Variants of Alzheimer's Disease and Vascular Dementia Patients in a Community Population of Nanking

, 10(8): 783 - 788

Wen-Zheng Chu, Li Gong, Ying-Qiu Xu, Guo-Hua Cai and Kuo-Chen Chou


DOI: 10.2174/1573406410666140327120714



Synthesis of 2`-hydroxy-4`-isoprenyloxychalcone Derivatives with Potential Antidepressant-like Activity

, 10(8): 789 - 799

Chao Xie, Zhou Peng, Shui-Lian Zhao, Cheng-Yan Pan, Li-Ping Guan and Xian-Yu Sun


DOI: 10.2174/1573406410666140328125641



Design, Synthesis and Pharmacological Evaluation of N3 Aryl/ Heteroaryl Substituted 2-((Benzyloxy and Phenylthio) Methyl) 6,7- dimethoxyquinazolin-4(3H)-ones as Potential Anticonvulsant Agents

, 10(8): 800 - 809

Nirupam Das, Anupam G. Banerjee and Sushant K. Shrivastava


DOI: 10.2174/1573406410666140402152044



Synthesis, Crystal Structure, Anti-inflammatory and Anti-hyperglycemic Activities of Novel 3,4-Disubstituted 1,2,4-Triazol-5(4H)-one Derivatives

, 10(8): 810 - 823

Muhammad Saleem, Seon-Mi Yu, Muhammad Rafiq, Song-Ja Kim, Sung-Yum Seo and Ki Hwan Lee


DOI: 10.2174/1573406410666140327142912



Benzothiazole Derivatives: Novel Inhibitors of Methylglyoxal Mediated Glycation of Proteins In Vitro

, 10(8): 824 - 835

Sanaullah Abbasi, Salma Mirza, Saima Rasheed, Shafqat Hussain, Jalaluddin A.J. Khan, Khalid Mohammed Khan, Shahnaz Perveen and Muhammad Iqbal Choudhary


DOI: 10.2174/1573406410666140331230953



Development of Thieno[3`,2`:5,6]thiopyrano[4,3-c]pyrazole-3-carboxamide Derivatives as the Estrogen Receptor Ligands: Synthesis, Characterization and Biological Activity

, 10(8): 836 - 842

Xin Wang, Rui Sun, Yushu Huang, Yisi Yan, Miaomiao Gao, Dan-Ni Wang, Diwa Koirala, Da-Wei Li and Chun Hu


DOI: 10.2174/1573406410666140428145753



Syntheses and N-methyl-D-aspartate Receptor Antagonist Pharmacology of Fluorinated Arylcycloheptylamines

, 10(8): 843 - 852

Shengguo Sun, Jason Wallach and Adeboye Adejare


DOI: 10.2174/1573406410666140428104444





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