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Medicinal Chemistry

Volume 17, 10 Issues, 2021
ISSN: 1875-6638 (Online)
ISSN: 1573-4064 (Print)
This journal supports open access


Medicinal Chemistry, Volume 10 - Number 5

The Survey of the Use of QSAR Methods to Determine Intestinal Absorption and Oral Bioavailability During Drug Design

, 10(5): 441 - 448

Fredson Torres Silva and Gustavo H.G. Trossini

DOI: 10.2174/1573406410666140415122115

Development, Validation and Application of an LC-MS/MS Bioanalytical Method for the Quantification of GF449, A Novel 5-HT1A Agonist, in Rat Plasma and Brain

, 10(5): 449 - 459

Silvia Franchini, Laura Taddia, Diego Pinetti, Gianluca Carnevale and Livio Brasili

DOI: 10.2174/1573406409666131128150507

Synthesis, Pharmacological Activity and Molecular Modeling of 1-Aryl-7- hydroxy-2,3-dihydroimidazo[1,2-a]pyrimidine-5(1H)-ones and their 6-Substituted Derivatives

, 10(5): 460 - 475

Marzena Rzadkowska, Elzbieta Szacon, Agnieszka A. Kaczor, Sylwia Fidecka, Ewa Kedzierska and Dariusz Matosiuk

DOI: 10.2174/1573406409666131128145844

Synthesis and In vitro Analysis of Novel Dihydroxyacetophenone Derivatives with Antimicrobial and Antitumor Activities

, 10(5): 476 - 483

Ana Maria Zbancioc, Anca Miron, Cristina Tuchilus, Pincu Rotinberg, Cosmin Teodor Mihai, Ionel I. Mangalagiu and Gheorghita Zbancioc

DOI: 10.2174/15734064113096660070

Discovery of Aroyl Piperazine Derivatives as IKr & IKs Dual Inhibitors for Cardiac Arrhythmia Treatment

, 10(5): 497 - 505

Xiaoke Guo, Haopeng Sun, Lvpei Du, Lu Huang, Jing Xu, Yingying Zhu, Peng Yu, Xiaojin Zhang, Yiqun Tang and Qidong You

DOI: 10.2174/1573406409666131128144755

Synthesis and Preliminary Biological Evaluation of Polyamine-aniline Acridines as P-glycoprotein Inhibitors

, 10(5): 506 - 511

Jianhong Wang, Pengfei Cheng, Tianwei Luo, Zhaoyi Wang, Yahong Zhang and Jin Zhao

DOI: 10.2174/15734064113096660052

An Efficient Ionic Liquid Mediated Synthesis, Cholinesterase Inhibitory Activity and Molecular Modeling Study of Novel Piperidone Embedded α ,β-Unsaturated Ketones

, 10(5): 512 - 520

Yalda Kia, Hasnah Osman, Raju Suresh Kumar, Vikneswaran Murugaiyah, Alireza Basiri, Kooi Yeong Khaw and Mohd. Mustaqim Rosli

DOI: 10.2174/15734064113096660056

Synthesis, Antioxidant, Anticancer and Antiviral Activities of Novel Quinoxaline Hydrazone Derivatives and their Acyclic C-Nucleosides

, 10(5): 521 - 532

Alaa A. El-Tombary and Soad A.M. El-Hawash

DOI: 10.2174/15734064113096660069

Synthesis of Aryl-Substituted Naphthalenoids as Potent Topoisomerase Inhibitors

, 10(5): 533 - 539

Yan Shen, Wang Chen, Zhenyu Li and Yuemao Shen

DOI: 10.2174/15734064113096660048


Dimitra Hadjipavlou-Litina
Department of Pharmaceutical Chemistry, School of Pharmacy
Aristotle University of Thessaloniki
View Full Editorial Board

Nobel Laureate on Editorial Board

Prof. Ferid Murad

COPE Compliant

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Journal History

Medicinal Chemistry Journal was launched in 2005. Dr. Dimitra Hadjipavlou-Litina serves as the Editor-in-Chief of the journal.

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