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Medicinal Chemistry

Volume 16, 8 Issues, 2020
ISSN: 1875-6638 (Online)
ISSN: 1573-4064 (Print)
This journal supports open access
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    Chemistry, Medicinal

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Contents

Medicinal Chemistry, Volume 10 - Number 5

The Survey of the Use of QSAR Methods to Determine Intestinal Absorption and Oral Bioavailability During Drug Design

, 10(5): 441 - 448

Fredson Torres Silva and Gustavo H.G. Trossini


DOI: 10.2174/1573406410666140415122115



Development, Validation and Application of an LC-MS/MS Bioanalytical Method for the Quantification of GF449, A Novel 5-HT1A Agonist, in Rat Plasma and Brain

, 10(5): 449 - 459

Silvia Franchini, Laura Taddia, Diego Pinetti, Gianluca Carnevale and Livio Brasili


DOI: 10.2174/1573406409666131128150507



Synthesis, Pharmacological Activity and Molecular Modeling of 1-Aryl-7- hydroxy-2,3-dihydroimidazo[1,2-a]pyrimidine-5(1H)-ones and their 6-Substituted Derivatives

, 10(5): 460 - 475

Marzena Rzadkowska, Elzbieta Szacon, Agnieszka A. Kaczor, Sylwia Fidecka, Ewa Kedzierska and Dariusz Matosiuk


DOI: 10.2174/1573406409666131128145844



Synthesis and In vitro Analysis of Novel Dihydroxyacetophenone Derivatives with Antimicrobial and Antitumor Activities

, 10(5): 476 - 483

Ana Maria Zbancioc, Anca Miron, Cristina Tuchilus, Pincu Rotinberg, Cosmin Teodor Mihai, Ionel I. Mangalagiu and Gheorghita Zbancioc


DOI: 10.2174/15734064113096660070




Discovery of Aroyl Piperazine Derivatives as IKr & IKs Dual Inhibitors for Cardiac Arrhythmia Treatment

, 10(5): 497 - 505

Xiaoke Guo, Haopeng Sun, Lvpei Du, Lu Huang, Jing Xu, Yingying Zhu, Peng Yu, Xiaojin Zhang, Yiqun Tang and Qidong You


DOI: 10.2174/1573406409666131128144755



Synthesis and Preliminary Biological Evaluation of Polyamine-aniline Acridines as P-glycoprotein Inhibitors

, 10(5): 506 - 511

Jianhong Wang, Pengfei Cheng, Tianwei Luo, Zhaoyi Wang, Yahong Zhang and Jin Zhao


DOI: 10.2174/15734064113096660052



An Efficient Ionic Liquid Mediated Synthesis, Cholinesterase Inhibitory Activity and Molecular Modeling Study of Novel Piperidone Embedded α ,β-Unsaturated Ketones

, 10(5): 512 - 520

Yalda Kia, Hasnah Osman, Raju Suresh Kumar, Vikneswaran Murugaiyah, Alireza Basiri, Kooi Yeong Khaw and Mohd. Mustaqim Rosli


DOI: 10.2174/15734064113096660056



Synthesis, Antioxidant, Anticancer and Antiviral Activities of Novel Quinoxaline Hydrazone Derivatives and their Acyclic C-Nucleosides

, 10(5): 521 - 532

Alaa A. El-Tombary and Soad A.M. El-Hawash


DOI: 10.2174/15734064113096660069



Synthesis of Aryl-Substituted Naphthalenoids as Potent Topoisomerase Inhibitors

, 10(5): 533 - 539

Yan Shen, Wang Chen, Zhenyu Li and Yuemao Shen


DOI: 10.2174/15734064113096660048




Editor-in-Chief

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
(Greece)

Biography View Full Editorial Board

Nobel Laureate on Editorial Board

Prof. Ferid Murad
(USA)

Journal History

Medicinal Chemistry Journal was launched in 2005. Dr. Dimitra Hadjipavlou-Litina serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.85

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