Medicinal Chemistry, Volume 1 - Number 5

Assessment In Vitro of a Novel Therapeutic Strategy for Glioma, Combining Herpes Simplex Virus HSV1716-mediated Oncolysis with Gene Transfer and Targeted Radiotherapy

, 1(5): 423 - 429

M. Quigg, R. J. Mairs, S. M. Brown, J. Harland, P. Dunn, R. Rampling, A. Livingstone, L. Wilson and M. Boyd

DOI: 10.2174/1573406054864124

Interaction Field Based and Hologram Based QSAR Analysis of Propafenone-type Modulators of Multidrug Resistance

, 1(5): 431 - 444

D. Kaiser, M. Smiesko, S. Kopp, P. Chiba and G. F. Ecker

DOI: 10.2174/1573406054864061

Comparison of (+)- and (-)-Hemipalmitoylcarnitinium as Inhibitors of Hepatic Mitochondrial Carnitine Palmitoyltransferases in Diabetic Rats

, 1(5): 445 - 453

P. S. Savle, N. E. Neptune, Y. Yang, J. H. Rouden, B. L. Kite, E. W. Sugandhi, R. V. Macri, K. Kashfi and R. D. Gandour

DOI: 10.2174/1573406054864115

Free Energy Perturbation Calculations on Glucosidase-Inhibitor Complexes

, 1(5): 455 - 460

F. M. Ruiz and J. R. Grigera

DOI: 10.2174/1573406054864151

Statin Attenuates High Glucose-Induced and Angiotensin II-Induced MAP Kinase Activity Through Inhibition of NAD(P)H Oxidase Activity in Cultured Mesangial Cells

, 1(5): 461 - 468

H. Y. Yu, T. Inoguchi, M. Nakayama, H. Tsubouchi, N. Sato, N. Sonoda, S. Sasaki, K. Kobayashi and H. Nawata

DOI: 10.2174/1573406054864052

ICG-001, A Novel Small Molecule Regulator of TCF/β-Catenin Masakatsu Transcription

, 1(5): 467 - 472

M. Eguchi, C. Nguyen, S. C. Lee and M. Kahn

DOI: 10.2174/1573406054864098

Enantioselective Synthesis and Preliminary Pharmacological Evaluation of the Enantiomers of Unifiram (DM232), a Potent Cognition-Enhancing Agent

, 1(5): 473 - 480

E. Martini, C. Ghelardini, C. Bertucci, S. Dei, F. Gualtieri, L. Guandalini, D. Manetti, S. Scapecchi, E. Teodori and M. N. Romanelli

DOI: 10.2174/1573406054864142

New Features in Synthesis of Talampanel Related 2,3-Benzodiazepines

, 1(5): 481 - 485

S. Solyom, I. Pallagi, G. Abraham, M. Kertesz, G. Horvath and P. Berzsenyi

DOI: 10.2174/1573406054864133

3D Solution Structure of [Tyr3]Octreotate Derivatives in DMSO: Structure Differentiation of Peptide Core Due to Chelate Group Attachment and Biologically Active Conformation

, 1(5): 487 - 499

G. A. Spyroulias, A. S. Galanis, Ch. Petrou, D. Vahliotis, P. Sotiriou, A. Nikolopoulou, B. Nock, T. Maina and P. Cordopatis

DOI: 10.2174/1573406054864089

N-Terminal Anthranoyl-Phenylalanine Derivatives as CCK1 Receptor Antagonists: The Final Approach

, 1(5): 501 - 517

A. Varnavas, L. Lassiani, V. Valenta, A. Ciogli, F. Gasparrini, L. Mennuni and F. Makovec

DOI: 10.2174/1573406054864070

Failure and Success in Modern Drug Discovery: Guiding Principles in the Establishment of High Probability of Success Drug Discovery Organizations

, 1(5): 519 - 527

G. M. Rishton

DOI: 10.2174/1573406054864106

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