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Medicinal Chemistry

Volume 15, 8 Issues, 2019
ISSN: 1875-6638 (Online)
ISSN: 1573-4064 (Print)
This journal supports open access

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  • 31st of 61 in

    Chemistry, Medicinal

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Abstracts Ahead of Print

Synthesis of N-Substituted Benzamide Derivatives and their Evaluation as Antitumor Agents


Taiping Chen, Hongwu Jiang, Jianjun Zhou, Zicheng Li*, Wencai Huang, Youfu Luo and Yinglan Zhao


DOI: 10.2174/1573406415666190712120611
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Synthesis and Antitrypanosomal Profile of Novel Hydrazonoyl Derivatives


Natália N. Santiago, Giulianna P. de Alcântara, Juliana Silva da Costa, Samir A. Carvalho, Juliana M. C. Barbosa, Kelly Salomão, Solange L. de Castro, Henrique M. G. Pereira and Edson F. da Silva*


DOI: 10.2174/1573406415666190712115237
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Design of Inhibitors for Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) Enzyme of Leishmania mexicana


Krisnna Mariana Aranda Alves, Fábio José Bonfim Cardoso, Kathia Maria Honorio and Fábio Alberto de Molfetta*


DOI: 10.2174/1573406415666190712111139
View Abstract



Synthesis and Assessment of 3-Substituted Phenazines as Novel Antichlamydial Agents


Xiaofeng Bao, Ziyi Liu, Min Ni, Chao Xia, Shunxin Xu, Shengju Yang* and Yu Zhao


DOI: 10.2174/1573406415666190708145639
View Abstract



Identification of novel functionalized carbohydrazonamides designed as Chagas disease drug candidates


Mayara Salles Souza do Nascimento, Vitória Regina Fontes Câmara, Juliana Silva da Costa, Juliana M. Chaves Barbosa, Alessandra Silva Maia Lins, Kelly Salomão, Solange Lisboa de Castro, Samir Aquino Carvalho, Edson Ferreira da Silva and Carlos Alberto Manssour Fraga*


DOI: 10.2174/1573406415666190627103013
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Synthesis of Novel 8-Hydroxyquinoline Derivatives through Mannich Reaction and their Biological Evaluation as Potential Immunomodulatory Agents


Shaheen Faizia*, Tahira Sarfaraz, Saima Sumbul, Almas Jabeen, Sobia Ahsan Halim, Mohammad Ahmed Mesaik and Zaheer Ul-Haq


DOI: 10.2174/1573406415666190626121650
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New Serotoninergic Ligands Containing Indolic and Methyl Indolic Nuclei: Synthesis and in Vitro Pharmacological Evaluation


Elisa Magli, Beatrice Severino*, Angela Corvino, Elisa Perissutti, Francesco Frecentese, Irene Saccone, Flavia Giordano, Marian Castro, Josè Brea, Marian Isabel Loza, Vincenzo Santagada, Giuseppe Caliendo and Ferdinando Fiorino


DOI: 10.2174/1573406415666190613153220
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Design, synthesis and biological evaluation of anti-tuberculosis agents based on Bedaquiline structure


Chengjun Wu*, Jinghan Luo, Mengtong Wu, Fanzhen Meng, Zhiqiang Cai, Yu Chen and Tiemin Sun


DOI: 10.2174/1573406415666190613094433
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2-Mercapto Benzothiazole Derivatives: As Potential Leads for the Diabetic Management


Saeed Ullah, Salma Mirza, Uzma Salar, Shafqat Hussain, Kulsoom Javaid, Khalid Mohammed Khan*, Ruqaiya Khalil, Atia Tul Wahab, Zaheer Ul-Haq, Shahnaz Perveen and M. Iqbal Choudhary


DOI: 10.2174/1573406415666190612153150
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Synthesis, In vitro α-Glucosidase Inhibitory Potential and Molecular Docking Studies of 2-Amino-1,3,4-Oxadiazole Derivatives


Hayat Ullah, Fazal Rahim*, Muhammad Taha, Raffaqat Hussain, Abdul Wadood, Mohsan Nawaz, Zainul Wahab, Kanwal and Khalid Mohammed Khan


DOI: 10.2174/1573406415666190612150447
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Novel p-Functionalized Chromen-4-on-3-yl Chalcones Bearing Astonishing Boronic Acid Moiety as MDM2 Inhibitor: Synthesis, Cytotoxic Evaluation and Simulation Studies


Richa Kaur Bhatia*, Lakhwinder Singh, Ruchika Garg, Maninder Kaur, Manmohan Yadav, Jitender Madan, Satyavathi Kancherla, Raghuvir R. S. Pissurlenkar and Evans C. Coutinho


DOI: 10.2174/1573406415666190531123751
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Design, Synthesis and Evaluation of 8-Thiosubstituted 1,3,7-Trimethylxanthine Hydrazones with In Vitro Neuroprotective and MAO-B Inhibitory Activities


Javor Mitkov, Alexandra Kasabova-Angelova, Magdalena Kondeva-Burdina, Virginia Tzankova, Diana Tzankova, Maya Georgieva and Alexander Zlatkova*


DOI: 10.2174/1573406415666190531121927
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Synthesis of new cyclic imides derived from safrole, structure- and ligand-based approaches to evaluate potential new multitarget agents against spe-cies of Leishmania


José Alixandre de Sousa Luis*, Normando Alexandre da Silva Costa, Cristiane Cosmo Silva Luis, Bruno Freitas Lira, Petrônio Filgueiras Athayde-Filho, Tatjana Keesen de Souza Lima, Juliana da Câmara Rocha, Luciana Scotti and Marcus Tullius Scotti


DOI: 10.2174/1573406415666190430144950
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Anti-Mycobacterial Peroxides: A new class of agents for development against tuberculosis


Christiaan W. van der Westhuyzen, Richard K. Haynes, Jenny-Lee Panayides, Ian Wiid and Christopher J. Parkinson*


DOI: 10.2174/1573406415666190430143535
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First example of antiparasitic activity influenced by thermochromism: Leishmanicidal evaluation of 5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidine metal complexes


José M. Méndez-Arriaga*, Itziar Oyarzabal, Álvaro Martín-Montes, Judith García-Rodríguez, Miguel Quirós and Manuel Sánchez-Moreno


DOI: 10.2174/1573406415666190401120607
View Abstract




Editor-in-Chief

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

Biography View Full Editorial Board

Journal History

Medicinal Chemistry Journal was launched in 2005. Dr. Dimitra Hadjipavlou-Litina serves as the Editor-in-Chief of the journal.
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