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Medicinal Chemistry

Volume 15, 8 Issues, 2019
ISSN: 1875-6638 (Online)
ISSN: 1573-4064 (Print)
This journal supports open access

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  • 31st of 61 in

    Chemistry, Medicinal

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Abstracts Ahead of Print

Fluoroquinolone-3-carboxamide amino acid conjugates: Synthesis, antibacterial properties and molecular modeling studies


Riham M. Bokhtia, Siva S. Panda*, Adel S. Girgis, Hitesh H. Honkanadavar, Tarek S. Ibrahim, Amany M. M. Al-Mahmoudy, Riham F. George, Mona T. Kashef, Walid Fayad, Rajeev Sakhuja and Eatedal H. Abdel-Aal


DOI: 10.2174/1573406415666190904143852
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Novel furan coupled quinoline diamide hybrid scaffolds as potent antitubercular agents: Design, synthesis and molecular modelling


Anantacharya Rajpurohit, Satyanarayan Nayak Devappa*, Lokesh Pathak, Siva Ayyanar, Chidambaram Ramaswamy Rishinaradamangalam and Praveen Shoorapani


DOI: 10.2174/1573406415666190904124630
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The antioxidant, anticarcinogenic and antimicrobial properties of Verbascum thapsus L.


Saman Mahdavi*, Morteza Amiradalat, Marzieh Babashpour, Hosein Sheikhlooei and Mohammad Miransari


DOI: 10.2174/1573406415666190828155951
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Improvement of the Anticancer Activity of Chlorambucil and Ibuprofen via Calix[4]arene Conjugates


Luis D. Pedro-Hernández, Ulises Organista-Mateos, Luis Isaac Allende-Alarcón, Elena Martínez-Klimova*, Teresa Ramírez-Ápan and Marcos Martínez-García


DOI: 10.2174/1573406415666190826162339
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New Insights Towards 1,4-Benzodiazepines from Curcumin. Design, Synthesis and Antimicrobial Activities


Othman Hamed*, Oswa Fares, Shaima Taleeb, Ghaleb Adwan, Haythem Saadeh, Shehdeh Jodeh and Manuel Algarra


DOI: 10.2174/1573406415666190826160251
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ROS Inhibitory Activity and Cytotoxicity Evaluation of Benzoyl, Acetyl, Alkyl Ester, and Sulfonate Ester Substituted Coumarin Derivatives


Uzma Salar, Khalid Mohammed Khan*, Almas Jabeen, Aisha Faheem, Farwa Naqvi, Shakil Ahmed, Erum Iqbal, Farman Ali, Kanwal and Shahnaz Perveen


DOI: 10.2174/1573406415666190826153001
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Study of interactions energies between residues of the active site of Hsp90 and the geldanamycin analogues using Quantum Mechanics/Molecular Mechanics (QM/MM) methods


Ricardo Vivas-Reyes, Alejandro Morales-Bayuelo, Carlos Gueto, Juan C. Droso, Johana Márquez, Rosa Baldiris, Maicol Ahumedo, Catalina Vivas-Gomez and Dilia Aparicio


DOI: 10.2174/1573406415666190724142113
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Methoxychalcones: Effect of Methoxyl Group toward Antifungal, Antibacterial and Antiproliferative Activities


Beatriz C. Marques, Mariana B. Santos, Daiane B. Anselmo, Diego A. Monteiro, Eleni Gomes, Marilia F. C. Saiki, Paula Rahal, Pedro L. Rosalen, Janaina C. O. Sardi and Luis O. Regasini


DOI: 10.2174/1573406415666190724145158
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Synthetic Dihydropyridines as Novel Antiacanthamoebic Agents


Ayaz Anwar*, Ruqaiyyah Siddiqui, Abdul Hameed, Muhammad Raza Shah and Naveed Ahmed Khan


DOI: 10.2174/1573406415666190722113412
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Synthesis and Cholinesterase Inhibitory Activity of N-Phosphorylated / N-Tiophosphorylated Tacrine


Maja Przybyłowska, Iwona Inkielewicz-Stepniak, Szymon Kowalski, Krystyna Dzierzbicka*, Sebastian Demkowicz and Mateusz Daśko


DOI: 10.2174/1573406415666190716115524
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4-Aminocoumarin based aroylthioureas as potential jack bean urease inhibitors; Synthesis, enzyme inhibitory kinetics and docking studies


Tanzeela Abdul Fattah, Aamer Saeed, Zaman Ashraf, Qamar Abbas, Pervaiz Ali Channar, Fayaz Ali Larik and Mubashir Hassan


DOI: 10.2174/1573406415666190715164834
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Synthesis and Antitrypanosomal Profile of Novel Hydrazonoyl Derivatives


Natália N. Santiago, Giulianna P. de Alcântara, Juliana Silva da Costa, Samir A. Carvalho, Juliana M. C. Barbosa, Kelly Salomão, Solange L. de Castro, Henrique M. G. Pereira and Edson F. da Silva*


DOI: 10.2174/1573406415666190712115237
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Synthesis and Assessment of 3-Substituted Phenazines as Novel Antichlamydial Agents


Xiaofeng Bao, Ziyi Liu, Min Ni, Chao Xia, Shunxin Xu, Shengju Yang* and Yu Zhao


DOI: 10.2174/1573406415666190708145639
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Synthesis of Novel 8-Hydroxyquinoline Derivatives through Mannich Reaction and their Biological Evaluation as Potential Immunomodulatory Agents


Shaheen Faizia*, Tahira Sarfaraz, Saima Sumbul, Almas Jabeen, Sobia Ahsan Halim, Mohammad Ahmed Mesaik and Zaheer Ul-Haq


DOI: 10.2174/1573406415666190626121650
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New Serotoninergic Ligands Containing Indolic and Methyl Indolic Nuclei: Synthesis and in Vitro Pharmacological Evaluation


Elisa Magli, Beatrice Severino*, Angela Corvino, Elisa Perissutti, Francesco Frecentese, Irene Saccone, Flavia Giordano, Marian Castro, Josè Brea, Marian Isabel Loza, Vincenzo Santagada, Giuseppe Caliendo and Ferdinando Fiorino


DOI: 10.2174/1573406415666190613153220
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2-Mercapto Benzothiazole Derivatives: As Potential Leads for the Diabetic Management


Saeed Ullah, Salma Mirza, Uzma Salar, Shafqat Hussain, Kulsoom Javaid, Khalid Mohammed Khan*, Ruqaiya Khalil, Atia Tul Wahab, Zaheer Ul-Haq, Shahnaz Perveen and M. Iqbal Choudhary


DOI: 10.2174/1573406415666190612153150
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Synthesis, In vitro α-Glucosidase Inhibitory Potential and Molecular Docking Studies of 2-Amino-1,3,4-Oxadiazole Derivatives


Hayat Ullah, Fazal Rahim*, Muhammad Taha, Raffaqat Hussain, Abdul Wadood, Mohsan Nawaz, Zainul Wahab, Kanwal and Khalid Mohammed Khan


DOI: 10.2174/1573406415666190612150447
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Editor-in-Chief

Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece

Biography View Full Editorial Board

Journal History

Medicinal Chemistry Journal was launched in 2005. Dr. Dimitra Hadjipavlou-Litina serves as the Editor-in-Chief of the journal.
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