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University of Sydney, Australia

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Thank you for your mail. I am very delighted to be the author of this article in your esteemed journal (Medicinal Chemistry, Bentham science publishers ). Glad to say that the quality of your service is very nice. I will surely contribute new research publication to this esteemed journal soon.

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(National Institute for Science and Technology on Innovation on Neglected Diseases (INCT/IDN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Brazil)


Medicinal Chemistry

,

Volume 14

-

Number 6



Biography



Research Article

Antibacterial Assessment of Heteroaryl, Vinyl, Benzyl, and Alkyl Tetrazole Compounds

, 14(6): 550 - 555

Joshua Dudley, Liana Feinn, Heather DeFrancesco, Erica Lindsay, Adiel Coca* and Elizabeth Lewis Roberts


DOI: 10.2174/1573406413666171120162420




Research Article

Anti-Trypanosoma cruzi Activity in vitro of Phases and Isolated Compounds from Excoecaria lucida Leaves

, 14(6): 556 - 562

Cristiane F. da Silva*, Ania O. Pacheco, Rayane N. Alves, Josean F. Tavares, Marcelo S. da Silva and Julio C.E. Arranz


DOI: 10.2174/1573406414666180112112154




Research Article



Research Article

Evaluation of Trypanocidal and Antioxidant Activities of a Selected Series of 3-amidocoumarins

, 14(6): 573 - 584

Mauricio Moncada-Basualto, Michel Lapier, Juan Diego Maya, Betty Matsuhiro, Claudio Olea-Azar*, Giovanna L. Delogu, Eugenio Uriarte, Lourdes Santana and Maria Joao Matose*


DOI: 10.2174/1573406414666180419113437




Research Article



Research Article



Research Article

Construction of an M1GS Ribozyme for Targeted and Rapid mRNA Cleavage; Application on the Ets-2 Oncogene

, 14(6): 604 - 616

Chrisavgi Toumpeki, Dimitrios Anastasakis, Ioannis Panagoulias, Vassiliki Stamatopoulou, Tassos Georgakopoulos, Sofia Kallia-Raftopoulos, Athanasia Mouzaki* and Denis Drainas*


DOI: 10.2174/1573406414666180112115201




Medicinal Chemistry, Volume 14 (2018) - Number 7


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Design, Synthesis and Investigation of New Diphenyl Substituted Pyridazinone Derivatives as Both Cholinesterase and Aβ-Aggregation Inhibitors


Burcu Kilic, Merve Erdogan, Hayrettin O. Gulcan, Fatma Aksakal, Nihan Oruklu, E. Umit Bagriacik and Deniz S. Dogruer*


View Abstract View on PubMed


Benzophenone Esters and Sulfonates: Synthesis and their Potential as Antiinflammatory Agents


Arshia, Almas Jabeen, Aisha Faheem, Khalid Mohammed Khan*, Shazia Shah and Shahnaz Perveen


View Abstract View on PubMed


Synthesis and Evaluation of the in vitro Antimicrobial Activity of Triazoles, Morpholine and Thiosemicarbazones


Felipe R. S. Santos, Jessica T. Andrade, Carla D. F. Sousa, Joice S. Fernandes, Lucas F. Carmo, Marcelo G. F. Araujo, Jaqueline M. S. Ferreira and Jose A. F. P. Villar*


View Abstract View on PubMed


Synthetic Diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates Induce Apoptosis


Seunghyun Ahn, Youngshim Lee, Jihyun Park, Junho Lee, Soon Young-Shin, Young Han Lee, Dongsoo Koh* and Yoongho Lim*


View Abstract View on PubMed


4-Hydroxy-2-pyridone Derivatives and the δ-pyrone Isostere as Novel Agents Against Mycobacterium smegmatis Biofilm Inhibitors


Maheshkumar R. Borkar, Santosh Nandan*, M N Harish Kumar , Jayashree Puttur, M Jisha , Dipankar Chatterji and Evans C. Coutinho *


View Abstract View on PubMed


Synthesis & Anticancer Evaluation of New Substituted 2-(3,4- Dimethoxyphenyl)benzazoles


Cigdem Karaaslan , Yalcin Duydu, Aylin Ustundag , Can Ozgur Yalcin, Banu Kaskatepe and Hakan Goker*


View Abstract View on PubMed


Synthesis and Structural Elucidation of Novel Benzothiazole Derivatives as Anti-tubercular Agents: In-silico Screening for Possible Target Identification


Katharigatta N. Venugopala*, Sandeep Chandrashekharappa, Melendhran Pillay, Subhrajyoti Bhandary, Mahmoud Kandeel, Fawzi M. Mahomoodally , Mohamed A. Morsy, Deepak Chopra , Bandar E. Aldhubiab, Mahesh Attimarad, Osama I. Alwassil , Sree Harsha and Koleka Mlisana


View Abstract View on PubMed


Neuropharmacological Screening of Chiral and Non-chiral Phthalimide- Containing Compounds in Mice: in vivo and in silico Experiments


Carolina Campos-Rodriguez, Jose G. Trujillo-Ferrara*, Ameyali Alvarez-Guerra, Iran M. Cumbres Vargas, Roberto I. Cuevas-Hernandez, Erik Andrade-Jorge, Sergio Zamudio and Eduardo Ramirez-San Juan*


View Abstract View on PubMed


Synthesis and Biological Evaluation of Novel 2,3-disubstituted Benzofuran Analogues of GABA as Neurotropic Agents


Arturo Coaviche-Yoval, Hector Luna, Ricardo Tovar-Miranda, Marvin Antonio Soriano-Ursua and Jose G. Trujillo-Ferrara*


View Abstract View on PubMed


Novel Hydroxamic Acids Incorporating 1-((1H-1,2,3-Triazol-4-yl)methyl)- 3-substituted-2-oxoindolines: Synthesis, Biological Evaluation and SAR Analysis


Do Thi Mai Dung, Nguyen Van Huan, Do Manh Cam, Dao Cam Hieu, Pham-The Hai, Le-Thi-Thu Huong, Jisung Kim, Jeong Eun Choi, Jong Soon Kang, Sang-Bae Han* and Nguyen-Hai Nam*


View Abstract View on PubMed


Abstracts Ahead of Print


Rational design of colchicine derivatives as anti-HIV agents via QSAR and molecular docking


Apilak Worachartcheewan*, Napat Songtawee, Suphakit Siriwong, Supaluk Prachayasittikul*, Chanin Nantasenamat and Virapong Prachayasittikul


View Abstract


ZnO Nanoparticles catalyst in Synthesis of Bioactive Fused Pyrimidines as Anti-breast Cancer Agents Targeting VEGFR-2


Dina H. Dawood, Eman M. H. Abbas, Thoraya A. Farghaly*, Mamdouh M. Ali and Mohammed F. Ibrahim


View Abstract


Synthesis of new thiosemicarbazones and semicarbazones containing the 1,2,3-1H-triazole-isatin scaffold: trypanocidal, cytotoxicity, electrochemical assays, and molecular docking


Bianca N. M. Silva, Policarpo A. Sales , Alvaro J. Romanha, Silvane M. F. Murta, Camilo H. S. Lima, Magaly G. Albuquerque, Eliane D'Elia, Jose G. de Aquino, Vitor F. Ferreira, Fernando C. Silva, Angelo C. Pinto and Barbara V. Silva*


View Abstract


Synthesis, molecular modeling and biological evaluation of 5-arylidene-N,N-diethylthiobarbiturates as potential α-glucosidase inhibitors


Momin Khan*, Sehrish Khan, Amir Ul Mulk, Anis Ur Rahman, Abdul Wadood, Sulaiman Shams, Muhammad Ashraf, Jameel Rahman, Abdul Hameed, Zahid Hussain, Abbas Khan, Khair Zaman, Khalid Mohammed Khan and Shahnaz Perveen


View Abstract


Ligand-Based Drug Design: Synthesis and Biological Evaluation of Substituted Benzoin Derivatives as Potential Antitumor Agents


Dima A. Sabbah*, Ameerah Hasan Ibrahim, Wamidh H. Talib, Khalid M. Alqaisi, Kamal Sweidan, Sanaa K. Bardaweel, Ghassan Abu Sheikha, Haizhen A. Zhong, Eveen Al-Shalabi, Reema Abu Khalaf and Mohammad S. Mubarak


View Abstract


Anticancer Activity and Topoisomerase II Inhibition of Naphthalimides with ω-Hydroxylalkylamine Side-Chains of Different Lengths


Mateusz D. Tomczyk, Anna Byczek Wyrostek, Klaudia Strama, Martyna Wawszków, Przemysław Kasprzycki and Krzysztof Z. Walczak*


View Abstract


Synthesis and biological evaluation of novel osthol derivatives as potent cytotoxic agents


Saleem Farooq*, Javid A. Banday*, Aashiq Hussain, Momina Nazir, Mushtaq A. Qurishi, Abid Hamid and S. Koul*


View Abstract


New Hybrid Scaffolds based on Hydrazinyl Thiazole Substituted Coumarin; As Novel Leads of Dual Potential; In Vitro α-Amylase Inhibitory and Antioxidant (DPPH and ABTS Radical Scavenging) Activities


Uzma Salar, Khalid Mohammed Khan*, Sridevi Chigurupati, Shazia Syed, Shantini Vijayabalan, Abdul Wadood, Muhammad Riaz, Mehreen Ghufran and Shahnaz Perveen


View Abstract


Essential oil from Lippia origanoides (Verbenaceae): haemostasis and enzymes activity alterations


Maria Luisa Teixeira, Silvana Marcussi, Danubia Aparecida de Carvalho Selvati Rezende, Maisa Lamounier Magalhaes, David Lee Nelson and Maria das Gracas Cardoso


View Abstract


Open Access Articles

Day/Night and Summer/Winter Changes in Serum Total Antioxidant Capacity

, 2018; 14(3): 225 - 229

Armando L. Morera-Fumero*, Pedro Abreu-Gonzalez, Manuel Henry-Benitez, Lourdes Fernandez-Lopez, Estefania Diaz-Mesa, Maria del Rosario Cejas-Mendez and Fernando Guillen-Pino




IRS-1 pY612 and Akt-1/PKB pT308 Phosphorylation and Antiinflammatory Effect of Diindolylmethane in Adipocytes Cocultured with Macrophages

, 2017; 13(8): 727 - 733

Alfonso Lopez-Vazquez, Jesus J. Garcia-Banuelos*, Angelica S. Gonzalez-Garibay, Pedro E. Urzua-Lozano, Susana Del Toro-Arreola, Miriam R. Bueno-Topete, Sergio Sanchez-Enriquez, Jose F. Munoz-Valle, Luis F. Jave-Suarez, Juan Armendariz-Borunda and Blanca E. Bastidas-Ramirez*




Long Term Stability Evaluation of Prostacyclin Released from Biomedical Device through Turbiscan Lab Expert

, 2015; 11(4): 391 - 399

Christian Celia, Marcello Locatelli, Felisa Cilurzo, Donato Cosco, Emanuela Gentile, Daniela Scalise, Maria Carafa, Cinzia Anna Ventura, Mathias Fleury, Christelle Tisserand, Renato. C Barbacane, Massimo Fresta, Luisa Di Marzio and Donatella Paolino




Practical Application of Antidiabetic Efficacy of Lycium barbarum Polysaccharide in Patients with Type 2 Diabetes

, 2015; 11(4): 383 - 390

Huizhen Cai, Fukang Liu, Pingguo Zuo, Guiling Huang, Zhixiu Song, Tingting Wang, Huixia Lu, Fei Guo, Chao Han and Guiju Sun





Synthesis of New Thiazolo[4,5-d]pyrimidines as Corticotropin Releasing Factor Modulators

, 2015; 11(1): 50 - 59

Bhimanna Kuppast, Katerina Spyridaki, Christophina Lynch, Yueshan Hu, George Liapakis, Gareth E. Davies and Hesham Fahmy





Most Cited Articles




miRNAs as Circulating Biomarkers for Alzheimer’s Disease and Parkinson’s Disease

, 2016; 12(3): 217-225.

Gohar Mushtaq, Nigel H. Greig, Firoz Anwar, Mazin A. Zamzami, Hani Choudhry, Munvar M. Shaik, Ian A. Tamargo and Mohammad A. Kamal


DOI: 10.2174/1573406411666151030112140


Growth Factors and Astrocytes Metabolism: Possible Roles for Platelet Derived Growth Factor

, 2016; 12(3): 204-210.

Ricardo Cabezas, Marco Avila-Rodriguez, Nelson E. Vega-Vela, Valentina Echeverria, Janneth González, Oscar A. Hidalgo, Altair B. Santos, Gjumrakch Aliev and George E. Barreto


DOI: 10.2174/1573406411666151019120444


Recent Updates on the Association Between Alzheimer’s Disease and Vascular Dementia

, 2016; 12(3): 226-237.

Ghulam M. Ashraf, Sandesh Chibber, Mohammad, Syed K. Zaidi, Shams Tabrez, Ausaf Ahmad, Shazi Shakil, Gohar Mushtaq, Saleh S. Baeesa and Mohammad A. Kamal


DOI: 10.2174/1573406411666151030111820


Discovery of Flexible Naphthyltriazolylmethane-based Thioacetic Acids as Highly Active Uric Acid Transporter 1 (URAT1) Inhibitors for the Treatment of Hyperuricemia of Gout

, 2017; 13(3): 260-281.

Xiansheng Zhang, Jingwei Wu, Wei Liu, Yuqiang Liu, Yafei Xie, Qian Shang, Zhixing Zhou, Weiren Xu, Lida Tang, Jianwu Wang and Guilong Zhao*


DOI: 10.2174/1573406412666160915163002



New N,N,N’,N’-tetradentate Pyrazoly Agents: Synthesis and Evaluation of their Antifungal and Antibacterial Activities

, 2016; 12(1): 83-89.

Farid Abrigach, Btissam Bouchal, Olivier Riant, Yohan Mace, Abdelilah Takfaoui, Smaail Radi, Abdelouahad Oussaid, Mohammed Bellaoui and Rachid Touzani


DOI: 10.2174/1573406411666150519111800



Most Accessed Articles

USP7: Target Validation and Drug Discovery for Cancer Therapy

, 2018; 14(1): 3-18.

Jin Zhou*, Jinzheng Wang, Chao Chen, Haoliang Yuan, Xiaoan Wen* and Hongbin Sun*


DOI: 10.2174/1573406413666171020115539


Day/Night and Summer/Winter Changes in Serum Total Antioxidant Capacity

, 2018; 14(3): 225-229.

Armando L. Morera-Fumero*, Pedro Abreu-Gonzalez, Manuel Henry-Benitez, Lourdes Fernandez-Lopez, Estefania Diaz-Mesa, Maria del Rosario Cejas-Mendez and Fernando Guillen-Pino


DOI: 10.2174/1573406413666171002123158


New Perspectives of Alzheimer Disease Diagnosis – the Most Popular and Future Methods

, 2018; 14(1): 34-43.

Katarzyna Pietrzak, Kamila Czarnecka, Elzbieta Mikiciuk-Olasik and Pawel Szymanski*


DOI: 10.2174/1573406413666171002120847


Drug Design, Synthesis and In Vitro Evaluation of Substituted Benzofurans as Hsp90 Inhibitors

, 2018; 14(1): 44-52.

Sundeep Kadasi, Thadeu E.M.M. Costa, Neha Arukala, Mallika Toshakani, Chaitanya Duggineti, Sreekanth Thota, Sayan D. Gupta, Shiva Raj, Carmen Penido, Maria G. Henriques and Nulgumnalli M. Raghavendra*


DOI: 10.2174/1573406413666170623085534



Discovery of Multi-target Anticancer Agents Based on HDAC Inhibitor MS-275 and 5-FU

, 2016; 12(1): 30-36.

Yuqi Jiang, Xiaoguang Li, Xiaoyang Li, Jinning Hou, Yongzheng Ding, Jian Zhang, Wenfang Xu and Yingjie Zhang


DOI: 10.2174/1573406411666150714111045


Identification of 1-Aryl-1H-1,2,3-triazoles as Potential New Antiretroviral Agents

, 2018; 14(3): 242-248.

Daniel T.G. Gonzaga, Thiago M.L. Souza, Viviane M.M. Andrade, Vitor F. Ferreira and Fernando de C. da Silva*


DOI: 10.2174/1573406413666170906121318


Synthesis and Antibacterial Activity Against MRSA of Pleuromutilin Derivatives Possessing a Mercaptoethylamine Linker

, 2018; 14(6): 585-594.

Zhao-Sheng Zhang, Yun-Zhen Huang, Jian Luo, Bing-Feng Wang, Zhen Jin, Ya-Hong Liu and You-Zhi Tang*


DOI: 10.2174/1573406414666180416131737



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