ISSN: 1875-6638 (Online)
ISSN: 1573-4064 (Print)


Volume 13, 8 Issues, 2017


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Medicinal Chemistry

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Dimitra Hadjipavlou-Litina


Aristotle University of Thessaloniki
Thessaloniki
Greece


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"Medicinal Chemistry is an invaluable journal, which contains the latest outstanding developments in medicinal chemistry. It is recommended to all scientists working in this field."

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University of Sydney, Australia

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Medicinal Chemistry

,

Volume 13

-

Number 8



Review Article

The Role of QSAR and Virtual Screening Studies in Type 2 Diabetes Drug Discovery

, 13(8): 706 - 720

Simone Q. Pantaleao, Drielli G.V. Fujii, Vinicius G. Maltarollo, Danielle da C. Silva, Gustavo H.G. Trossini, Karen C. Weber, Luis P.B. Scott and Kathia M. Honorio*


DOI: 10.2174/1573406413666170522152102


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Research Article

Isolation of Chlorogenic Acid from Soil Borne Fungi Screlotium rolfsii, their Reversal of Multidrug Resistance and Anti-proliferative in Mouse Lymphoma Cells

, 13(8): 721 - 726

Bashir Ahmad, Muhammad Rizwan, Abdur Rauf *, Muslim Raza, Shumaila Bashir , Joseph Molnar, Akos Csonka, Diana Szabo, Mohammad S. Mubarak, Mah Noor and Bina S. Siddiqui


DOI: 10.2174/1573406413666170612110443


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Research Article

IRS-1 pY612 and Akt-1/PKB pT308 Phosphorylation and Antiinflammatory Effect of Diindolylmethane in Adipocytes Cocultured with Macrophages

, 13(8): 727 - 733

Alfonso Lopez-Vazquez, Jesus J. Garcia-Banuelos*, Angelica S. Gonzalez-Garibay, Pedro E. Urzua-Lozano, Susana Del Toro-Arreola, Miriam R. Bueno-Topete, Sergio Sanchez-Enriquez, Jose F. Munoz-Valle, Luis F. Jave-Suarez, Juan Armendariz-Borunda and Blanca E. Bastidas-Ramirez*


DOI: 10.2174/1573406413666170922095011


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Research Article

Design, Synthesis, and Biological Evaluation of C-2 Substituted 3Hthieno[ 2,3-d]pyrimidin-4-one Derivatives as Novel FGFR1 Inhibitors

, 13(8): 753 - 760

Ping Guo, Zixin Xie, Huan Zhang, Zaikui Zhang , Chao Han , Donghua Cheng, Dan Lin, Yuan Zhang, Xuebao Wang, Xin Guo and Faqing Ye *


DOI: 10.2174/1573406413666170623084525


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Research Article

Synthesis and Biological Evaluation of Curcumin-Nitroxide-Based Molecular Hybrids as Antioxidant and Anti-Proliferative Agents

, 13(8): 761 - 772

Balazs Bognar, M. Lakshmi Kuppusamy, Esha Madan, Tamas Kalai, Maria Balog, Jozsef Jeko, Periannan Kuppusamy and Kalman Hideg*


DOI: 10.2174/1871520617666170522124712


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Synthesis, Structure and Antiproliferative Activity of New pyrazolo[4,3- e]triazolo[4,5-b][1,2,4]triazine Derivatives


Mariusz Mojzych*, Pawel Tarasiuk, Zbigniew Karczmarzyk, Malgorzata Juszczak, Wojciech Rzeski, Andrzej Fruziński and Artur Wozny


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9-(4'-dimethylaminophenyl)-2,6,7-trihydroxy-xanthene-3-one is a Potentially Novel Antiplatelet Drug which Antagonizes the Effect of Thromboxane A2


Lenka Applova, Elma Veljovic, Samija Muratovic, Jana Karlickova, Katerina Macakova, Davorka Završnik, Luciano Saso, Kemal Duric and Premysl Mladenka*


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The Quantum Chemical and QSAR Studies on Acinetobacter Baumannii Oxphos Inhibitors


Hakan Sezgin Sayiner*, Afaf A.S. Abdalrahm, Murat A. Başaran, Vasyl Kovalishyn and Fatma Kandemirli*


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Day/Night and Summer/Winter Changes in Serum Total Antioxidant Capacity


Armando L. Morera-Fumero*, Pedro Abreu-Gonzalez, Manuel Henry-Benitez, Lourdes Fernandez-Lopez, Estefania Diaz-Mesa, Maria del Rosario Cejas-Mendez and Fernando Guillen-Pino


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Synthesis and structure-activity relationship exploration of some potent anti-cancer phenyl amidrazone derivatives


Almeqdad Y. Habashneh, Mustafa M. El-Abadelah, Sanaa K Bardaweel and Mutasem O. Taha*


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Activity of rifabutin and hemi-synthetic derivatives against Mycobacterium abscessus


Ivy B. Ramis*, Ricardo Figueiredo, Daniela F. Ramos, Priscila C.B. Halicki, Andrea von Groll, Miguel Viveiros, Maria do Ceu Costa and Pedro E.A. da Silva


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Synthesis and in vitro antioxidant activity study of some novel substituted piperazinyl flavone compounds


Elmas Sari, Paweł Berczynski, Aleksandra Kładna, Irena Kruk, Oya B Dundar, Monika Szymanska and Hassan Y. Aboul-Enein*


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Prodrugs For Nitroreductase Based Cancer Therapy- 1 Metabolite Profile, Cell Cytotoxicity and Molecular Modeling Interactions of Nitro Benzamides with Ssap-NtrB


Tugba Gungor, Gulden Yetis, Ferah Cömert Onder, Esra Tokay, Tugba Taşkın Tok, Ayhan Celik, Mehmet Ay* and Feray Kockar


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Xanthine Oxidase Inhibitory and Molecular Docking Studies on Pyrimidones


Humaira Zafar, Sarosh Iqbal, Sumaira Javaid, Khalid M. Khan* and Muhammad I. Choudhary*


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A novel method to synthesize phosphocreatine and phosphocreatine prodrugs


Maria Arkel, Patrizia Garbati, Annalisa Salis, Gianluca Damonte, Nara Liessi, Enrico Adriano, Umberto Benatti, Maurizio Balestrino and Enrico Millo*


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Antibacterial Assessment of Heteroaryl, Vinyl, Benzyl, and Alkyl Tetrazole Compounds


Joshua Dudley, Liana Feinn, Heather DeFrancesco, Erica Lindsay, Adiel Coca* and Elizabeth Lewis Roberts


View Abstract



Inhibition of Adipogenesis by Thiourea Derivatives


Hina Siddiqui*, Sarah Shafi, Farah Mukhtar, Asma Ejaz, Atta-ur-Rahman and M. Iqbal Choudhary*


View Abstract



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