Contents

Letters in Drug Design & Discovery, Volume 8 - Number 4

Graphical Abstracts

, 8(4): i - v


DOI: 10.2174/157018011794839457




The Antiangiogenic and Antitumoral Activity of Titanocene Y* In Vivo

, 8(4): 302 - 307

Iduna Fichtner, Diana Behrens, James Claffey, Anthony Deally, Brendan Gleeson, Siddappa Patil, Holger Weber and Matthias Tacke


DOI: 10.2174/157018011794839367




Synthesis of Some Coumarinyl Chalcones and their Antiproliferative Activity Against Breast Cancer Cell Lines

, 8(4): 308 - 311

Kuldeep Patel, Chandrabose Karthikeyan, Viswas Raja Solomon, N. S. Hari Narayana Moorthy, Hoyun Lee, Kapendra Sahu, Girdhar Singh Deora and Piyush Trivedi


DOI: 10.2174/157018011794839475




Synthesis of (6,7-dimethoxy-2-oxo-2H-chromen-4-yl)methyl 3-Arylacrylates as Water Soluble Antitumor Agents

, 8(4): 312 - 316

Nguyen-Hai Nam, Ngo Anh Ngoc and Ahn Byung Zun


DOI: 10.2174/157018011794839466




Synthesis and Characterization of some Novel Quinoxaline-2, 3-Dione Derivatives: A Preliminary Investigation on their Activity Against a Human Epithelial Carcinoma Cell Line

, 8(4): 317 - 320

Selvaraj Jubie, Rajamanickam Gayathri, Ammayappan Rajam Srividya, Rajagopal Kalirajan, Prabakaran Prabitha, Sundaram Sankar and Kannan Elango


DOI: 10.2174/157018011794839385




Vagus Nerve Stimulation as a Treatment for Refractory Epilepsy: A 15-Year Experience in an Italian Tertiary – Care Epilepsy Center

, 8(4): 321 - 329

Chiara Pizzanelli, Renato Galli, Filippo S. Giorgi, Alfonso Iudice, Enrica Bonanni, Veronica Pelliccia, Stella Jensen, Laura Manca, Bruno Lenzi, Ludovico Lutzemberger, Giuliano Parenti, Francesco Fornai and Luigi Murri


DOI: 10.2174/157018011794839394




Synthesis and Anxiolytic Activity of Some Novel 5-oxo-1, 4-oxazepine Derivatives

, 8(4): 330 - 338

Bothiana A. AbdelFattah, Maha M.A. Khalifa, Hend El-Sehrawi, Eman Fayed, Ashraf Bayoumi and Makarem Said


DOI: 10.2174/157018011794839448




3D-QSAR and Docking Studies of 4-morpholinopyrrolopyrimidine Derivatives as Potent mTOR Inhibitors

, 8(4): 339 - 354

Shao-Teng Wang, Yong Ai, Chu Tang, Fa-Jun Song and Ping-Hua Sun


DOI: 10.2174/157018011794839493




In Silico Identification of Small Molecule Mimetics of the Pro-Apoptotic BH3-Helix

, 8(4): 355 - 362

Melanie Fullbeck, Julia Hossbach, Ines S. Jaeger, Peter T. Daniel and Robert Preissner


DOI: 10.2174/157018011794839484




Molecular Docking with Trehalose-6 Phosphate Phosphatase: A Potential Drug Target of Filaral Parasite ‘Brugia malayi’

, 8(4): 363 - 370

Lakshminarayanan Karthik, Palayam Malathy, Annie Trinitta and Krishnasamy Gunasekaran


DOI: 10.2174/157018011794839402




Antimalarial Activity of an N-Alkyl Diamine

, 8(4): 371 - 374

Nicolli B. de Souza, Carlos A. M. Rezende, Marcela S. Toledo, Davi C. Lagatta, Raphaela V. T. de Oliveira, Cristiane F. da Costa, Adilson D. da Silva, Marcio J. M. Alves, Sonia M. N. Cupolilo, Mauro V. de Almeida and Clarice Abramo


DOI: 10.2174/157018011794839439




Antiviral Activity of 3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol and its Derivatives Against Influenza A(H1N1)2009 Virus

, 8(4): 375 - 380

Oleg V. Ardashov, Vladimir V. Zarubaev, Anna A. Shtro, Dina V. Korchagina, Konstantin P. Volcho, Nariman F. Salakhutdinov and Oleg I. Kiselev


DOI: 10.2174/157018011794839411




Transdermal Delivery of Acyclovir Sodium Via Carbopol Gels: Role of Chemical Permeation Enhancers

, 8(4): 381 - 389

Raju Jukanti, Ashok Mateti, Suresh Bandari and Prabhakar R Veerareddy


DOI: 10.2174/157018011794839420




Thermodynamic and Kinetic Aspects of the Lipid Peroxidation of Arachidonic Acid

, 8(4): 390 - 400

Claire Claire E. Tornow, Betsy Lau and M. C. Milletti


DOI: 10.2174/157018011794839376




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