Contents

Letters in Drug Design & Discovery, Volume 8 - Number 2

Graphical Abstracts

, 8(2): i - iv


DOI: 10.2174/157018011794183879




Editorial [Hot Topic Progress in Fighting the Multidrug Resistance of Bacteria to Treatment (Guest Editor: Mihail-Lucian Pascu)]

, 8(2): 100

Mihail-Lucian Pascu


DOI: 10.2174/157018011794183734




BM0701: Antibiotic Transport and Efflux: New Strategies to Combat Bacterial Resistance (ATENS)

, 8(2): 101

Jean-Marie Pages, Mihail-Lucian Pascu, Leonard Amaral, Ben Luisi, Gyorgy Hajos, Seamus Fanning and Peter Henderson


DOI: 10.2174/157018011794183824




Heterocyclic Compounds as MDR Modulators

, 8(2): 102 - 113

Gyorgy Hajos, Katalin Jemnitz, Zsuzsanna Riedl, Daniella Takacs and Zsuzsa Veres


DOI: 10.2174/157018011794183815




Mechanisms of Antibiotic Resistance in Salmonella: Efflux Pumps, Genetics, Quorum Sensing and Biofilm Formation

, 8(2): 114 - 123

Marta Martins, Matthew McCusker, Leonard Amaral and Seamus Fanning


DOI: 10.2174/157018011794183770




Time Stability Studies of Quinazoline Derivative Designed to Fight Drug Resistance Acquired by Bacteria

, 8(2): 124 - 129

Andra Militaru, Adriana Smarandache, Abdallah Mahamoud, Sandrine Alibert, Jean-Marie Pages and Mihail-Lucian Pascu


DOI: 10.2174/157018011794183752




Thioridazine: Alternative and Potentially Effective Therapy of the XDRTB Patient

, 8(2): 130 - 132

Leonard Amaral, Marta Martins and Miguel Viveiros


DOI: 10.2174/157018011794183860




Quorum Sensing Inhibition by Phenothiazines and Related Compounds

, 8(2): 133 - 137

Zoltan Gabor Varga, Mira Agnes Szabo, Zsuzsanna Schelz, Erno Szegedi, Leonard Amaral and Jozsef Molnar


DOI: 10.2174/157018011794183789




Synthesis and Comparison of the Antitumor Activities of Steroids on ABCB1-transfected Mouse Lymphoma and Human Ovary Carcinoma

, 8(2): 138 - 147

Julianna Serly, Iren Vincze, Csaba Somlai, Laszlo Hodoniczki and Jozsef Molnar


DOI: 10.2174/157018011794183833




Expression of P-gp, MRP, LRP, GST-π and TopoIIα and Acquired Resistance to Cisplatin in Human Lung Adenocarcinoma Cells

, 8(2): 148 - 153

Jiarui Wang, Zhongzhou He, Lichuan Zhang, Encheng Li, Qiang Meng, Lijuan Zou, Joseph Molnar and Qi Wang


DOI: 10.2174/157018011794183743




Synthesis and Biological Evaluation of Gemfibrozil Chiral Analogues as Potential PPARα Agonists

, 8(2): 154 - 158

Barbara De Filippis, Letizia Giampietro, Antonella Giancristofaro, Alessandra Ammazzalorso, Marialuigia Fantacuzzi, Cristina Maccallini, Michele Petruzzelli and Rosa Amoroso


DOI: 10.2174/157018011794183761




Integrated Web-Based ab initio Modeling Platform for G-protein Coupled Receptors

, 8(2): 159 - 171

Govindan Subramanian, Manish Sud, Sam Billakanti and Adel Laoui


DOI: 10.2174/157018011794183798




Search of QSAR Models for Predicting the Antiprotozoal Activity and Cytotoxicity In Vitro of a Group of Pentamidine Analogous Compounds

, 8(2): 172 - 180

Ramon Garcia-Domenech, Isabel Denise Manhenje, Yamileth Monje, Adassa Lopez-Gonzalez, Rafael Marco, Catalina Tacho and Jorge Galvez


DOI: 10.2174/157018011794183851




The Global Component-Target Network in Panax Ginseng C

, 8(2): 181 - 188

Fan Zhang, Chun-Yang Li, En-Qin Wang, Wen-Wen Li, Qi-Jia Yu, Xin Wen, Jun-Jie Liu and Jin-Ku Bao


DOI: 10.2174/157018011794183842




Synthesis and Biological Evaluation of Some [1,2,4]Triazolo[3,4-b][1,3,4]Thiadiazoles and [1,2,4]Triazolo[3,4-b][1,3,4]Thiadiazines

, 8(2): 189 - 200

Channamata Shankara Naveena, Boja Poojary, Chikkanna Chandrashekhar and Nalilu Suchetha Kumari


DOI: 10.2174/157018011794183806




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