Contents

Letters in Drug Design & Discovery, Volume 5 - Number 8

Telmisartan Blocks Advanced Glycation End Product (AGE)-Induced Plasminogen Activator Inhibitor-1 (PAI-1) Gene Expression in Endothelial Cells via Activation of Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ )

, 5(8): 477 - 480

Takanori Matsui, Kazuo Nakamura, Masayoshi Takeuchi and Sho-ichi Yamagishi


DOI: 10.2174/157018008786898590




Synthesis and Biological Evaluation of Novel 6-Deoxy-β -D-Psicofuranosyl Mercaptoheterocyclic Compounds

, 5(8): 481 - 484

I. G. De Lade, F. G. Braga, R. M. Grazul, E. S. Coimbra and A. D. Da Silva


DOI: 10.2174/157018008786898554




Microwave-Assisted Synthesis of Imido-Substituted 2-Chloro-1,4-naphthoquinone Derivatives and their Cytotoxic Activities on Three Human Prostate Cancer Cell Lines

, 5(8): 485 - 488

Solomon Berhe, Yasmine Kanaan, Robert L. Copeland Jr., Dwayne A. Wright, Leon H. Zalkow and Oladapo Bakare


DOI: 10.2174/157018008786898581




Antitumor Activity of Oxali-Titanocene Y in Xenografted CAKI-1 Tumors in Mice

, 5(8): 489 - 493

Iduna Fichtner, Diana Behrens, James Claffey, Brendan Gleeson, Megan Hogan, Denise Wallis, Holger Weber and Matthias Tacke


DOI: 10.2174/157018008786898545




Multidimensional Consensus QSAR: A Step towards Integrating CoMFA, CoMSIA with Traditional QSAR Methodologies (Supplementary Data)

, 5(8): 494 - 502

P. Dewangan, S. M. Verma, A. Basu and Venkatesan J.


DOI: 10.2174/157018008786898563




Synthesis of a Novel Series of 8-HETE Analogs and their Biological Evaluation Towards the PPAR Nuclear Receptors

, 5(8): 503 - 511

Melanie Liutkus, Catherine Dacquet, Valerie Audinot-Bouchez, Jean Boutin, Daniel-Henri Caignard, Alain Ktorza and Rene Gree


DOI: 10.2174/157018008786898572




Molecular Modeling of Flavonoid-β-Cyclodextrin Complexes

, 5(8): 512 - 520

Ying Zheng, Albert H.L. Chow and Ian S. Haworth


DOI: 10.2174/157018008786898536




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