Letters in Drug Design & Discovery, Volume 4 - Number 5

The Therapeutic Potential of Gallium-Based Complexes in Anti-Tumor Drug Design

, 4(5): 311 - 317

Michael Frezza, Claudio N. Verani, Di Chen and Q. Ping Dou

DOI: 10.2174/157018007780867799

Stereochemistry as a Determinant of the Anti-Leukemic Potency of Halopyridyl and Thiazolyl Thiourea Compounds

, 4(5): 318 - 326

Taracad K. Venkatachalam, Alexi O. Vassilev, Alexi Benyunov, Olga O. Grigoriants, Heather E. Tibbles and Fatih M. Uckun

DOI: 10.2174/157018007780867870

Synthesis and Chemical Characterization of N10-Substituted Acridones as Reversers of Multidrug Resistance in Cancer Cells

, 4(5): 327 - 335

Y.C. Mayur, Manjunath Gouda, Vadiraj S. Gopinath, S.M. Shanta Kumar and V.V.S. Rajendra Prasad

DOI: 10.2174/157018007780867834

The Tumor Necrosis Factor-Derived TIP Peptide: A Potential Anti-Edema Drug

, 4(5): 336 - 340

Rudolf Lucas, Harald Hundsberger, Maren Pfluger, Bernhard Fischer, Denis Morel, Clemens Braun, Albrecht Wendel, Trinad Chakraborty, Wolfgang Schutt, Christoph Wiesner and Jurg Hamacher

DOI: 10.2174/157018007780867816

Synthesis and Cytotoxic Activity of Cisplatin Analogue with an Ursodeoxycholate Ligand

, 4(5): 341 - 345

Martin Perez-Andres, Juan Jose Benito, Emilio Rodriguez-Fernandez, Juan Luis Manzano, Susana Barrena, Alberto Orfao and Julio Jose Criado

DOI: 10.2174/157018007780867898

Molecular Basis of Agonistic Activity of ERα17p, a Synthetic Peptide Corresponding to a Sequence Located at the N-Terminal Part of the Estrogen Receptor αLigand Binding Domain

, 4(5): 346 - 355

Dominique Gallo, Yves Jacquot, Anny Cleeren, Francoise Jacquemotte, Ioanna Laios, Guy Laurent and Guy Leclercq

DOI: 10.2174/157018007780867807

Hologram Quantitative Structure-Activity Relationships for a Class of Inhibitors of HIV-1 Protease

, 4(5): 356 - 364

Leonardo G. Ferreira, Andrei Leitao, Carlos A. Montanari and Adriano D. Andricopulo

DOI: 10.2174/157018007780867825

Design of Molecules Acting on the Serotonin Receptors

, 4(5): 365 - 367

Carmela Saturnino, Mariafrancesca Buonerba and Anna Capasso

DOI: 10.2174/157018007780867861

Intracerebroventricular Injection of Glutathione-Related Dipeptides Induces Sedative and Hypnotic Effects During Acute Stress in Neonatal Chicks

, 4(5): 368 - 372

Haruka Yamane, Rie Suenaga, Li Han, Kohsuke Hayamizu, D. Michael Denbow and Mitsuhiro Furuse

DOI: 10.2174/157018007780867843

Nicotinic and Glycinergic Medications for Disorders of Hedonic Regulation

, 4(5): 373 - 381

M.A. Dyer, R.S. Barr and A.E. Evins

DOI: 10.2174/157018007780867852

Synthesis and Biological Activities of New Triphenyl Organotin (IV) Based on the Pyrazole Carboxylic Acids

, 4(5): 382 - 385

Abderrahmane Yahyi, Abdelkader Ettouhami, Smaail Radi, Ismail Zidane, Abdelkader Hakkou and Mohamed Bouakka

DOI: 10.2174/157018007780867889

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