Letters in Drug Design & Discovery, Volume 4 - Number 2

Bortezomib: Proteasome Inhibition as a Novel Mechanism of Cancer Therapy-Implications for Hematological Malignancies

, 4(2): 82 - 86

Joesph Mikhael and Hong Chang

DOI: 10.2174/157018007779422541

Symmetrical Derivatives of C2-Substituted Pyrrolo[2,3-f]quinolines:Synthesis, Cytotoxicity and Drug Delivery Studies

, 4(2): 87 - 91

Andrew Tsotinis, Marilena Vlachou, Maria Gerasimopoulou, Aphrodite Eikosipentaki, Constantine Ioannidis, Anna Klouvidaki, Pandelis A. Afroudakis, Dimitri Moreau and Christos Roussakis

DOI: 10.2174/157018007779422488

Design, Synthesis and Evaluation of a Novel Polymer for Gene Delivery to Mammalian Cells

, 4(2): 92 - 98

Chandrashekhar Chittimalla, Deniz Dalkara and Guy Zuber

DOI: 10.2174/157018007779422569

Fragment Based Approach for the Investigation of HIV-1 Integrase Inhibition

, 4(2): 99 - 105

J. Polanski, H. Niedbala, R. Musiol, B. Podeszwa, D. Tabak, A. Palka, A. Mencel, J.-F. Mouscadet and M. Le Bret

DOI: 10.2174/157018007779422532

Classical and Hologram QSAR Studies on a Series of Tacrine Derivatives as Butyrylcholinesterase Inhibitors

, 4(2): 106 - 113

M. S. Castilho, R. V. C. Guido and A. D. Andricopulo

DOI: 10.2174/157018007779422505

Synthesis and In Vitro Inhibitory Potential Towards Urease of 9-Anilinoacridines and Aciridinyl Hydrazides

, 4(2): 114 - 121

Khalid Mohammed Khan, Nosheen Akbar Rao, M. Arif Lodhi, Shahnaz Perveen, M. Iqbal Choudhary and Wolfgang Voelter

DOI: 10.2174/157018007779422523

Response Surface Analysis as Alternative 3D-QSAR Tool: Human A3 Adenosine Receptor Antagonists as a Key Study

, 4(2): 122 - 127

Magdalena Bacilieri, Chosei Kaseda, Giampiero Spalluto and Stefano Moro

DOI: 10.2174/157018007779422460

Non-Covalent Binding of Disodium Disuccinate Astaxanthin to the Catalytic Site of Phosphodiesterase 5A: A Molecular Modeling Study

, 4(2): 128 - 136

Eszter Hazai, Zsolt Bikadi, Ferenc Zsila and Samuel F. Lockwood

DOI: 10.2174/157018007779422497

Design and In Vitro Evaluation of Five Inhibitors of Mycobacterium Tuberculosis

, 4(2): 137 - 143

Ronald Bartzatt, Suat L. G. Cirillo and Jeffrey D. Cirillo

DOI: 10.2174/157018007779422451

Design, Synthesis and Biological Testing of Cyclohexenone Derivatives of Combretastatin-A4

, 4(2): 144 - 148

Jennifer Ruprich, Andrew Prout, John Dickson, Brent Younglove, Lawrence Nolan, Khyati Baxi, Regan LeBlanc, Lori Forrest, Patrice Hills, Herman Holt Jr, Hilary Mackay, Toni Brown, Susan L. Mooberry and Moses Lee

DOI: 10.2174/157018007779422442

Synthesis and Antimicrobial Activity of Pyridine Derivatives Substituted at C-2 and C-6 Positions

, 4(2): 149 - 153

Mauro Vieira De Almeida, Marcus Vinicius de Nora Souza, Nadia Rezende Barbosa, Frederico Pittella Silva, Giovanni Wilson Amarante and Sílvia Helena Cardoso

DOI: 10.2174/157018007779422514

Synthesis and Antiparasitic Activity Against Trypanosoma cruzi and Leishmania amazonensis of Chlorinated 1,7- and 1,8-Naphthyridines

, 4(2): 154 - 159

Luiz Everson da Silva, Antonio Carlos Joussef, Leticia Kramer Pacheco, Danielle Bibas Legat Albino, Anita Mauricio Camilo Duarte, Mario Steindel and Ricardo Andrade Rebelo

DOI: 10.2174/157018007779422550

BXT-51072 and the Prevention of Myocardial Ischemia-Reperfusion Injury

, 4(2): 160 - 162

Roy Asaf, Shany Blum, Rachel Miller-Lotan and Andrew P. Levy

DOI: 10.2174/157018007779422479

Webmaster Contact:
Copyright © 2018 Bentham Science