Letters in Drug Design & Discovery, Volume 3 - Number 3

Evaluation of the Effects of a New Drug on Brain Leukocyte Infiltration in an Experimental Model of Autoimmune Encephalomyelitis

, 3(3): 138 - 148

A. Mangas, R. Covenas, D. Bodet, M. P. Dabadie, G. Glaize and M. Geffard

DOI: 10.2174/157018006776286943

Pt(II) vs Pd(II) Polyamine Complexes as New Anticancer Drugs: A Structure- Activity Study

, 3(3): 149 - 151

S. M. Fiuza, A. M. Amado, Paulo J. Oliveira, Vilma A. Sardao, L. A.E.B. de Carvalho and M. P.M. Marques

DOI: 10.2174/157018006776286989

Synthesis and Evaluation of Calpain Inhibitors Carrying Muscle Cell Targeting Groups

, 3(3): 152 - 158

P. Weyermann, H. Herzner, C. Lescop, H. Siendt, R. Bolliger, M. Hennebohle, C. Rummey, A. Briguet, I. Courdier-Fruh, M. Erb, M. Foster, J.P. Magyar, A. von Sprecher and T. Meier

DOI: 10.2174/157018006776286916

Regulation of MMP/TIMP Balance as Therapeutic Target in Pulmonary Diseases

, 3(3): 159 - 171

Corinne A.E. Martin-Chouly, Stephanie Guillot, Stephane Jouneau, Sylvie Caulet-Maugendre, Laurent Vernhet, Vincent Lagente and Philippe Delaval

DOI: 10.2174/157018006776287005

HIF-1α as a Target for Drug Design in Ischemic Injury: Effect of Cobalt Treatment on Mitochondrial DNA Damage in Cells Exposed to H2O2

, 3(3): 172 - 174

Yasutomo Nomura, Hiroyuki Fujiwara, Kohei Ito, Hirobumi Fuchigami, Michihiko Sato, Eiji Takahashi, Yasukazu Hozumi, Kaoru Goto, Zhonggang Feng and Takao Nakamura

DOI: 10.2174/157018006776286952

5-Hydroxy-6-Quinaldic Acid as a Novel Molecular Scaffold for HIV-1 Integrase Inhibitors

, 3(3): 175 - 178

J. Polanski, H. Niedbala, R. Musiol, B. Podeszwa, D. Tabak, A. Palka, A. Mencel, J. Finster, J.- F. Mouscadet and M. L. Bret

DOI: 10.2174/157018006776286934

Synthesis and Evaluation of Hypolipidemic Properties of some Novel Derivatives of Thieno Oxazine and 5-Hydroxyindole-2-Carboxylic Acid

, 3(3): 179 - 182

Sankar Mohan, K. A. Reddy, Javed Iqbal, Debnath Bhuniya and Saibal K. Das

DOI: 10.2174/157018006776287014

Inhibition of Geranyl-Geranyl Prenylation by Statins: A Novel Model of Disease Modification of Systemic Sclerosis

, 3(3): 183 - 187

Chris T. Derk

DOI: 10.2174/157018006776286998

Preparation of a Cyclodextrin Conjugated With Two Arbutin Moieties as a Drug-Carrier Model, and its High Ability for the Inclusion of Doxorubicin

, 3(3): 188 - 191

Takashi Yamanoi, Natsumi Kobayashi, Keiko Takahashi and Kenjiro Hattori

DOI: 10.2174/157018006776286925

Synthesis and Biological Activity of 4-Amino-1-Methyl-5-Imidazolecarboxylic Acid Derivatives

, 3(3): 192 - 199

A. Regiec, H. Mastalarz, R. Miedzybrodzki, K. Smietanska and R. Jasztold-Howorko

DOI: 10.2174/157018006776286961

Increasing the Odds of Drug Hit Identification by Screening Against Receptor Homologs?

, 3(3): 200 - 204

Z. L. Ji, Z. R. Li, J. F. Wang, C. Z. Cai, L. Y. Han, C. J. Zheng and Y. Z. Chen

DOI: 10.2174/157018006776286970

Synthesis and Biological Activity of New 4β-N-Heteroaryl Analogues of Podophyllotoxin

, 3(3): 205 - 209

Ahmed Kamal, B. A. Kumar, M. Arifuddin and Sunanda G. Dastidar

DOI: 10.2174/157018006776286907

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