Letters in Drug Design & Discovery, Volume 3 - Number 10

Prediction of the Conformation of the Human P2X7 Receptor

, 3(10): 675 - 682

Peter P. Mager, Peter Illes and Horst Walther

DOI: 10.2174/157018006778631929

The Chemokine CXCL10 as a Therapeutic Target in Animal Models of Neuroinflammatory Disease

, 3(10): 683 - 688

Rafael Gonzalez, Jenny L. Hardison, Janette Glaser, Michael T. Liu, Thomas E. Lane and Hans S. Keirstead

DOI: 10.2174/157018006778631839

Bridged Piperazines and Piperidines as CCR1 Antagonists with Oral Activity in Models of Arthritis and Multiple Sclerosis

, 3(10): 689 - 694

Laszlo Revesz, Birgit Bollbuck, Thomas Buhl, Janet Dawson, Roland Feifel, Richard Heng, Peter Hiestand, Helmut Sparrer, Achim Schlapbach, Rudolf Waelchli and Pius Loetscher

DOI: 10.2174/157018006778631866

Future Prospects for Old Chemotherapeutic Drugs in the Target-Specific Era; Pharmaceutics, Combinations, Co-Drugs and Prodrugs with Melphalan as an Example

, 3(10): 695 - 703

M. Wickstrom, H. Lovborg and J. Gullbo

DOI: 10.2174/157018006778631893

Optimization and Therapeutic Activity of Liposome-Conjugated Monoclonal Antibodies Against the ErbB family of Receptor Tyrosine Kinases: First Step in the Development of Therapeutic Antibody/Liposomal Anticancer Drug Combinations

, 3(10): 704 - 713

Gigi N.C. Chiu, Troy O. Harasym, Paul G. Tardi, Marcel B. Bally and Dawn N. Waterhouse

DOI: 10.2174/157018006778631884

Bleomycin-Induced Oxidative Stress and Lung Injury in Rats: Inhibition by Curcumin

, 3(10): 714 - 722

Durairaj Punithavathi, Mary Babu, Venkatesan Arumugam and Narayanan Venkatesan

DOI: 10.2174/157018006778631848

Relaxation Behavior and Crystallization Kinetics of Amorphous Acetaminophen

, 3(10): 723 - 730

Gopalakrishnan Trichy Rengarajan and Mario Beiner

DOI: 10.2174/157018006778631938

Maintenance Treatment of Opioid Dependence and Patterns of Non-Prescribed Drug Use: Results of a 4-Year Trial

, 3(10): 731 - 740

Salvatore M. Giacomuzzi, Markus Ertl, Marion Pavlic, Kathrin Libiseller, Yvonne Riemer, Georg Kemmler, Haimo Rossler, Petra Grubwieser, Walter Rabl and H. Hinterhuber

DOI: 10.2174/157018006778631910

Oleoylethanolamide: a Molecular Cross-Talk with Leptin in Feeding Behaviour Regulation

, 3(10): 741 - 746

Buenaventura Brito, Rafael Castro and Antonio Cabrera de Leon

DOI: 10.2174/157018006778631901

Synthesis and Preliminary Evaluation of L-Dopa/Benserazide Conjugates as Dual Acting Codrugs

, 3(10): 747 - 752

A. Di Stefano, P. Sozio, A. Iannitelli, A. Cocco, G. Orlando and M. Ricciutelli

DOI: 10.2174/157018006778631947

Gracilins G-I, Cytotoxic Bisnorditerpenes from Spongionella pulchella, and the Anti-Adhesive Properties of Gracilin B

, 3(10): 753 - 760

Ana Rueda, Alejandro Losada, Rogelio Fernandez, Carlos Cabanas, Luis F. Garcia- Fernandez, Fernando Reyes and Carmen Cuevas

DOI: 10.2174/157018006778631875

Synthesis and Biochemical Evaluation of a Range of Non-Substituted Phenyl Alkyl Triazole-Based Compounds as Potential Inhibitors of the Enzyme Complex 17α -Hydroxylase/17,20-Lyase (P45017α)

, 3(10): 761 - 765

Caroline P. Owen, Chirag H. Patel, Sachin Dhanani and Sabbir Ahmed

DOI: 10.2174/157018006778631857

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