Contents

Letters in Drug Design & Discovery, Volume 3 - Number 1


Preliminary Investigation of Structure-Activity Relationship of Cytotoxic Physalins

, 3(1): 9 - 13

H. I.F. Magalhaes, M. L. Veras, O. D.L. Pessoa, E. R. Silveira, M. O. Moraes, C. Pessoa and L. V. Costa-Lotufo


DOI: 10.2174/157018006775240917




Enhancement of Drug Cytotoxicity by Silicon Containing Groups

, 3(1): 29 - 34

Jose M. Padron, Osvaldo J. Donadel, Leticia G. Leon, Tomas Martin and Victor S. Martin


DOI: 10.2174/157018006775240944




Novel 5-HT7 Ligands as Antidepressants: Automated Synthesis of NSubstituted- N-[1-Methyl-3-(4-Methylpiperidin-1-yl)propyl]-Arylsulfonamides

, 3(1): 49 - 54

Eric Lattmann, Isidro Merino, Simon Dunn, Bushra Parveen, Pornthip Lattmann, David C. Billington, Yodchai Bunprakob and Jintana Sattayasai


DOI: 10.2174/157018006775240935



Pyrrolo[3,4-c]Quinoline-1,3-Diones as Potent Caspase-3 Inhibitors: Synthesis and SAR of 8-Sulfamoyl-1,3-Dioxo-2,3-Dihydro-1H-Pyrrolo[3,4- c]Quinolines

, 3(1): 61 - 70

Dmitri V. Kravchenko, Julia A. Kuzovkova, Volodymyr M. Kysil, Sergey E. Tkachenko, Sergey Malarchuk, Ilya M. Okun and Alexandre V. Ivachtchenko


DOI: 10.2174/157018006775240908



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