Contents

Letters in Drug Design & Discovery, Volume 2 - Number 7

Inhibitors of Hepatitis C Virus NS3.4A Protease: P2 Proline Variants

, 2(7): 497 - 502

Luc J. Farmer, Shawn D. Britt, Kevin M. Cottrell, John J. Court, Lawrence F. Courtney, David D. Deininger, Cynthia A. Gates, Scott L. Harbeson, Kai Lin, Chao Lin, Yu- P. Luong, John P. Maxwell, Janos Pitlik, B. G. Rao, Wayne C. Schairer, John A. Thomson, Roger D. Tung, John H. Van Drie, Yunyi Wei and Robert B. Perni


DOI: 10.2174/157018005774479203




Ximelagatran: An Oral Direct Thrombin Inhibitor for Anticoagulant Therapy

, 2(7): 503 - 506

Marco L. Rossi, Dennis Zavalloni, Guido Belli and Patrizia Presbitero


DOI: 10.2174/157018005774479168




Design of Selective Inhibitors of Tyrosine Kinase 2

, 2(7): 507 - 515

Kristin Tondel and Finn Drablos


DOI: 10.2174/157018005774479104




Selectivity of SB203580, SB202190 and Other Commonly Used p38 Inhibitors: Profiling Against a Multi-Enzyme Panel

, 2(7): 516 - 521

Jacqueline L. Norris, Kevin P. Williams, William P. Janzen, C. N. Hodge, Leonard J. Blackwell and Ioana G. Popa-Burke


DOI: 10.2174/157018005774479159




Quantitative Structure-Activity Relationship Studies on Matrix Metalloproteinase Inhibitors: Bicyclic Heteroaryl Hydroxamic Acid Analogs

, 2(7): 522 - 528

S. P. Gupta and S. Kumaran


DOI: 10.2174/157018005774479096




Synthesis and Anti-Breast Cancer Activity of Tetrasubstituted Pyrrole Derivatives

, 2(7): 529 - 532

Jose M. Padron, David Tejedor, Alicia Santos-Exposito, Fernando Garcia-Tellado, Jesus Villar and Victor S. Martin


DOI: 10.2174/157018005774479122




New Peptidic GnRH Antagonists Offer a Broad Range of Therapeutic Applications

, 2(7): 533 - 536

Engel J.B, Diedrich K and Honig A


DOI: 10.2174/157018005774479195




Synthesis and Evaluation of Some 16-Benzylidene Substituted 3,17- Dioximino Androstene Derivatives as Anticancer Agents

, 2(7): 537 - 545

Sonal Dubey, Poonam Piplani and Dharam P. Jindal


DOI: 10.2174/157018005774479186




Design Features that Affect Psychopharmacology Trials

, 2(7): 546 - 550

Arif Khan and Kelly Schwartza


DOI: 10.2174/157018005774479140




A Review of the Regulatory Role of Nicotinamide on Pro- and Anti-apoptotic Proteins in Neuronal Cells

, 2(7): 551 - 557

S. K. Mukherjee, M. Sonee and J. D. Adams Jr


DOI: 10.2174/157018005774479177




L-Dopa Related Hyperhomocysteinemia: A Possible Mediator of Toxicity?

, 2(7): 558 - 562

Stefano Zoccolella, Giovanni Iliceto, Michele deMari, Giovanni Defazio, Paolo Livrea and Paolo Lamberti


DOI: 10.2174/157018005774479113




Synthesis and Anti-Mycobacterial Activity of N-[(E)-(Disubstituted- Phenyl)Methylidene]Isonicotino-Hydrazide Derivatives

, 2(7): 563 - 566

Ivan N. Junior, Maria C. S. Lourenco, Maria das Gracas M. O. Henriques, Barbara Ferreira, Thatyana R. A. Vasconcelos, Monica A. Peralta, Pedro S. M. de Oliveira, Solange M. S. V. Wardell and Marcus V. N. de Souza


DOI: 10.2174/157018005774479131




Interaction of Furosemide with the Human Sodium-Dependent Dicarboxylate Transporter (hNaDC-3)

, 2(7): 567 - 570

Ingo Muller, Yohannes Hagos, Gerhard Burckhardt and Birgitta C. Burckhardt


DOI: 10.2174/157018005774479087




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