Contents

Letters in Drug Design & Discovery, Volume 2 - Number 2

Graphical Abstracts

, 2(2): v


DOI: 10.2174/157018081050202000v




Inhibition of Human Melanoma Cell Replication Using Protein Transduction Technology with a Uracil-DNA Glycosylase Inhibitor

, 2(2): 92 - 96

Maria E. Ariza, Irene Pedersen and M. V. Williams


DOI: 10.2174/1570180053175179




Mitotic Checkpoint: A Therapeutic Target in the Treatment of Human Cancer

, 2(2): 97 - 104

Xianghong Wang, Y. C. Wong and Dong-Yan Jin


DOI: 10.2174/1570180053175098




The Application of Angiotensin Converting Enzyme Inhibitors in Heart Surgery

, 2(2): 105 - 108

Yasuyuki Shimada


DOI: 10.2174/1570180053175124




Inhibition of BACE-1 by Hydroxyethylsulfide, Hydroxyethylamine and Hydroxyethylurea Isosteric Replacements

, 2(2): 109 - 112

L. Rizzi and S. Romeo


DOI: 10.2174/1570180053175142




The Role of an Amphiphilic Capping Group in Covalent and Non-Covalent Dipeptide Inhibitors of HCV NS3 Serine Protease

, 2(2): 113 - 117

Stefania Colarusso, Benjamin Gerlach, Claudio Giuliano, Uwe Koch, Victor G. Matassa and Frank Narjes


DOI: 10.2174/1570180053175089




P1 and P1; Optimization of [3,4]-Bicycloproline P2 Incorporated Tetrapeptidyl α-Ketoamide Based HCV Protease Inhibitors

, 2(2): 118 - 123

Shu-Hui Chen, Jason Lamar, Yvonne Yip, Frantz Victor, Robert B. Johnson, Q. May Wang, John I. Glass, Beverly Heinz, Joseph Colacino, Deqi Guo, Mark Tebbe and John E. Munroe


DOI: 10.2174/1570180053175115




Avidin Fusion Protein Strategies in Targeted Drug and Gene Delivery

, 2(2): 124 - 132

Olli H. Laitinen, Kari J. Airenne, Jani K. Raty, Thomas Wirth and Seppo Yla-Herttuala


DOI: 10.2174/1570180053175197




Synthesis and In Vitro Evaluation of Adenosine Deaminase Resistant N-6 Aminal and Thioaminal Prodrugs of Cordycepin

, 2(2): 133 - 136

Hui-Min Chang, Jesse Oakes, Anders Olsson, Luminita Panaitescu, B. Mark Britt, Christopher M. Kearney and Robert R. Kane


DOI: 10.2174/1570180053175151




Recognition of Specific DNA Sequences by Stacked Pyrrole- and Imidazole- Containing Polyamides: An Efficient Screening Method Based on Competitive Dialysis

, 2(2): 137 - 142

Karen L. Buchmueller, Sarah M. Horick, Cameron M. Howard, Peter B. Uthe, Andrew M. Staples, Suzanna L. Bailey, N. Minh Le, Kari K. Cox, James A. Henry and Moses Lee


DOI: 10.2174/1570180053175160




Neuroprotection in Huntington;s Disease

, 2(2): 143 - 147

Raphael M. Bonelli, Anna K. Hodl and Hans-Peter Kapfhammer


DOI: 10.2174/1570180053175133




Biodegradable Additives Modulate Ganciclovir Release Rate From PLGA Microspheres Destined to Intraocular Administration

, 2(2): 148 - 149

Emilia Barcia, Cristina Herradon and Rocío Herrero-Vanrell


DOI: 10.2174/1570180053175188




Anti-Viral Therapies for Hepatitis C Virus Infection: Current Options and Evolving Candidate Drugs

, 2(2): 150 - 161

Liam J. Fanning


DOI: 10.2174/1570180053175070




Activity of Amidine-containing Diphenylureas Against P. falciparum

, 2(2): 162 - 164

Guatam Bhattacharya, Lucia Gerena, Suping Jiang and Karl A. Werbovetz


DOI: 10.2174/1570180053175061




Tamarind Inhibits Solar-Simulated Ultraviolet Radiation-Induced Suppression of Recall Responses in Humans

, 2(2): 165 - 171

J. M. Kuchel, R. St. C. Barnetson, L. Zhuang, F. M. Strickland, R. P. Pelley and G. M. Halliday


DOI: 10.2174/1570180053175106




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