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Letters in Drug Design & Discovery

Volume 18, 12 Issues, 2021
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access

Contents

Letters in Drug Design & Discovery, Volume 17 - Number 5


Research Article

Bimetallic Catalyzed N-arylation Used in Synthesis of Novel β-carbolines Derivatives

, 17(5): 520 - 525

Rui Cai , Li Zhu, Pengfei Wang and Yu Zhao*


DOI: 10.2174/1570180815666181025124615



Research Article

Design, Synthesis and Antifungal Activity of Novel 1-(Adamantan-1-yl) ethanone Oxime Esters

, 17(5): 526 - 532

Si Liu, Li-Zhi Niu, Yan-Hua Shi, Fu-Xian Wan and Lin Jiang*


DOI: 10.2174/1570180816666190329225307



Research Article

Virtual Screening and In Silico Simulation Analysis for Rapid and Efficient Identification of Novel Natural GPR40 Agonist

, 17(5): 533 - 546

Virendra Nath, Rohini Ahuja and Vipin Kumar*


DOI: 10.2174/1570180815666180914162935



Research Article

Diversified Thiazole Substituted Coumarins and Chromones as Non- Cytotoxic ROS and NO Inhibitors

, 17(5): 547 - 555

Uzma Salar, Khalid Mohammed Khan*, Almas Jabeen, Shafquat Hussain, Aisha Faheem, Farwa Naqvi and Shahnaz Perveen


DOI: 10.2174/1570180816666190611155218



Research Article

Caffeic Acid Phenethyl Ester Effects: In Silico Study of its Osteoimmunological Mechanisms

, 17(5): 556 - 562

Yuhao Zhao, Xiaokun Pang, Akriti Nepal, Xincan Jiang, Xiaoxin Xu, Dongbin Zhao, Ghulam Murtaza* and Yanxu Ma*


DOI: 10.2174/1570180815666180803111902



Research Article

(Substituted)-benzo[b]thiophene-4-carboxamide Synthesis and Antiproliferative Activity Study

, 17(5): 563 - 573

Chandrakant Dhondiram Pawar, Dattatraya Navnath Pansare and Devanand Baburao Shinde*


DOI: 10.2174/1570180815666181004114125



Research Article

Synthesis, In vitro and In silico Evaluation of a Series of Pyrazolines as New Anticholinesterase Agents

, 17(5): 574 - 584

Mehlika Dilek Altıntop*


DOI: 10.2174/1570180816666190618111023



Research Article

Design of New Therapeutic Agents Targeting FLT3 Receptor Tyrosine Kinase Using Molecular Docking and 3D-QSAR Approach

, 17(5): 585 - 596

Swapnil Pandurang Bhujbal, Seketoulie Keretsu and Seung Joo Cho*


DOI: 10.2174/1570180816666190618104632



Research Article

Uses of Cyclohexan-1,3-dione for the Synthesis of Thiazole, Pyrazole, Thiophene, Isoxazole and Pyran Derivatives with Antitumor Activities

, 17(5): 597 - 609

Rafat Milad Mohareb, Nadia Youssef Megally Abdo* and Waleed Nabeel Al-darkazali


DOI: 10.2174/1570180816666190618115128



Research Article

Synthesis and In Vitro Biological Activity Evaluation of Novel Imidazo [2,1-B][1,3,4] Thiadiazole as Anti-Alzheimer Agents

, 17(5): 610 - 617

Sara Azimi, Omidreza Firuzi, Aida Iraji, Afsaneh Zonouzi , Mahsima Khoshneviszadeh, Mohammad Mahdavi* and Najmeh Edraki*


DOI: 10.2174/1570180816666181108115510



Research Article

Docking and 3D-QSAR Studies of Hydrazone and Triazole Derivatives for Selective Inhibition of GRK2 over ROCK2

, 17(5): 618 - 632

Seketoulie Keretsu, Swapnil Pandurang Bhujbal and Seung Joo Cho*


DOI: 10.2174/1570180816666190618105320



Research Article

Microwave-assisted Synthesis and Docking Studies of Phenylureas as Candidates for the Drug Design Against the Biological Warfare Agent Yersinia Pestis

, 17(5): 633 - 639

Tanos Celmar Costa França*, Leonardo da Costa Bastos, Teobaldo Cuya, Mehdi Sirouspour, Franklin Chacón-Huete, David Bendahan and Pat Forgione*


DOI: 10.2174/1570180816666190710144212



Research Article

Cytotoxic Activity and DNA Binding Property of New Aminopyrimidine Derivatives

, 17(5): 640 - 654

Hamidreza Akrami, Bibi Fatemeh Mirjalili, Omidreza Firuzi, Azadeh Hekmat, Ali Akbar Saboury, Ramin Miri, Omid Sabzevari, Morteza Pirali-Hamedani, Fereshteh Jeivad, Setareh Moghimi, Saeed Emami, Alireza Foroumadi* and Mehdi Khoobi*


DOI: 10.2174/1570180816666190712102119



Research Article

Lead Molecules as Novel Aromatase Inhibitors: In Silico De Novo Designing and Binding Affinity Studies

, 17(5): 655 - 665

Laxmi Banjare, Sant Kumar Verma, Akhlesh Kumar Jain and Suresh Thareja*


DOI: 10.2174/1570180816666190703152659



Letter

Azacyanines as Novel Topoisomerase II Alpha Inhibitors

, 17(5): 666 - 671

Sercan Guloglu, Fahriye Nur Kirmaci, Ozgul Persil Cetinkol*, Mehrdad Forough and Aybuke Gulkaya


DOI: 10.2174/1570180816666190628161945



Letters to the editor   Open Access

Current Strategies and Approaches in Combating SARS-CoV-2 Virus that Causes COVID-19

, 17(5): 672 - 674

D. Sivaraman*, P. S. Pradeep, S. Sundar Manoharan, C. Ramachandra Bhat, K. V. Leela and V. Venugopal


DOI: 10.2174/157018081705200403092546



Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)
Biography
View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 2.0

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