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Letters in Drug Design & Discovery

Volume 17, 12 Issues, 2020
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research


Letters in Drug Design & Discovery, Volume 17 - Number 4

Biography   Open Access

Review Article

Carbon Nanotubes Enhance the Chemotherapy Sensitivity of Tumors with Multidrug Resistance

, 17(4): 366 - 378

Zhijie Wang, Jinhua Tao, Jianan Chen and Qian Liu*

DOI: 10.2174/1570180816666190405110858

Review Article

Phage Display as A Bio-Technique for Cancer Immunotherapy

, 17(4): 379 - 387

Shirin Mahmoodi, Navid Nezafat* and Younes Ghasemi*

DOI: 10.2174/1570180816666190611160443

Research Article

3D-QSAR Studies on 4,5-Dihydro-1H-pyrazolo [4,3-h] Quinazolines as Plk-1, CDK2/A and Aur-A Serine/Threonine Kinase Inhibitors

, 17(4): 388 - 395

Bhoomendra A. Bhongade*, Nikhil D. Amnerkar* and Andanappa K. Gadad

DOI: 10.2174/1570180816666190611161332

Research Article

Synthesis of New 4-Chloro-6-Methylpyrimidin-2-yl-Aminophosphonates as Potential DU145 and A549 Cancer Cell Inhibitors

, 17(4): 396 - 410

Gajjala Raghavendra Reddy, Chinta Raveendra Reddy, Gopireddy Venkata Subba Reddy, Pasupuleti Visweswara Rao, Meenakshisundaram Swaminathan, Balam Satheeh Krishna and Cirandur Suresh Reddy*

DOI: 10.2174/1570180816666190329223207

Research Article

Antiglycation Activity of N, N-Diethylthiobarbiturates Derivatives

, 17(4): 411 - 417

Momin Khan*, Ghulam Ahad, Ajmal Khan, Sana Shah, Kanwal, Uzma Salar, Syed Muhammad Salman and Khalid Mohammed Khan*

DOI: 10.2174/1570180816666190516111516

Research Article

Design, Synthesis and In Vitro Evaluation of 2-Oxo-N-substituted Phenyl- 2H-chromene-3-carboxamide Derivatives as HIV Integrase Strand Transfer Inhibitors

, 17(4): 418 - 427

Pankaj Wadhwa*, Priti Jain and Hemant R. Jadhav

DOI: 10.2174/1570180816666190617150803

Research Article

In vitro and In Vivo Evaluation of Quinoxaline 1,4-di-N-oxide Against Giardia lamblia

, 17(4): 428 - 433

Elizabeth Barbosa-Cabrera, Rosa Moo-Puc, Antonio Monge, Alma Delia Paz-González, Virgilio Bocanegra-García and Gildardo Rivera*

DOI: 10.2174/1570180816666190618115854

Research Article

Synthesis, In Silico and In Vivo Evaluation of Novel 1, 3, 4-Thiadiazole Analogues as Novel Anticancer Agents

, 17(4): 434 - 444

Swathi Krishna, Byran Gowramma*, Manal Mohammed, Rajagopal Kalirajan, Lakshman Kaviarasan and Thaggikuppe Krishnamurthy Praveen*

DOI: 10.2174/1570180816666190710145939

Research Article

In Silico Elucidation of the Molecular Recognition of Phenol Derivative Compounds and Hippuryl-histidyl-leucine as an Artificial Substrate with the Experimental Target: Angiotensin-converting Enzyme

, 17(4): 445 - 466

Víctor Hugo Vázquez-Valaldez*, Manuel Alejandro Hernández S, Ivonne Carrillo Cedillo, Ana María Velázquez Sanchez, Mildred Sauce Guevara, Rafael López Castañares and Enrique Ángeles

DOI: 10.2174/1570180816666190906155034

Research Article

Studies on the pIC50 of 4,5-Diarylisoxazole as HSP90 Inhibitors

, 17(4): 467 - 478

Jing Ouyang, Xiaoqian Liu, Yutao Zhao, Ying Liu, Hongzong Si* and Honglin Zhai

DOI: 10.2174/1570180816666190329221959

Research Article

Evaluating Radioprotection of Rat’s Jejunum by a Combination of Melatonin and Metformin

, 17(4): 479 - 484

Nasim Ahmadi Azar, Abdolreza Javadi, Masoud Najafi*, Alireza Shirazi*, Elham Tajabadi, Dheyauldeen Shabeeb and Ahmed Eleojo Musa

DOI: 10.2174/1570180816666190617153004

Research Article

Synthesis of Thiazole, Thiophene, Pyran and Pyridine Derivatives Derived from 3-phenyl-1H-pyrazol-5(4H)-one with Anti-proliferative, Tyrosine Kinase and PIM-1 Kinase Inhibitions

, 17(4): 485 - 501

Rafat Milad Mohareb* and Ibram Refat Mikhail

DOI: 10.2174/1570180816666190618105907

Research Article

New Hydrazone Derivatives of Pyrazole-4-carboxaldehydes Exhibited Anti-inflammatory Properties

, 17(4): 502 - 511

Mingxia Song, Bing Liu, Shengwang Yu, Shihui He, Yuqiu Liang, Sifan Li, Qiuyan Chen and Xianqing Deng*

DOI: 10.2174/1570180816666190731113441

Research Article

Synthesis and Cytotoxicity of New Mannich Bases of 6-[3-(3,4,5-Trimetoxyphenyl)-2- propenoyl]-2(3H)-Benzoxazolone

, 17(4): 512 - 517

Ognyan Ivanov Petrov, Yordanka Borisova Ivanova*, Mariana Stefanova Gerova and Georgi Tsvetanov Momekov

DOI: 10.2174/1570180816666190730164952


K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05


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