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Letters in Drug Design & Discovery

Volume 17, 12 Issues, 2020
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research


Letters in Drug Design & Discovery, Volume 16 - Number 7

Research Article

Synthesis, Characterization, Free-radical Scavenging Capacity and Antioxidant Activity of Novel Series of Hydrazone, 1,3,4-oxadiazole and 1,2,4- triazole Derived from 3,5-dimethyl-1H-pyrazole

, 16(7): 712 - 720

Khalid Karrouchi*, Saad Fettach, Smaail Radi*, El bekkaye Yousfi, Jamal Taoufik, Yahia Nasser Mabkhot, Seham Alterary, My El Abbes Faouzi and Muhammed Ansar

DOI: 10.2174/1570180815666180516103050

Research Article

Design and Synthesis of Benzopyranopyrimidinyl Phosphonates as Cytotoxic and Antioxidant Agents

, 16(7): 721 - 733

Sarva Santhisudha, Gundluru Mohan, Tenkayala Sobha Rani, Peddaiahgari Vasu Govardhana Reddy and Cirandur Suresh Reddy*

DOI: 10.2174/1570180815666180606083418

Research Article   Open Access

Synthesis, Anti-inflammatory, Antimicrobial Potential and Molecular Docking Studies of 4,5-Disubstituted-1,2,4-Triazole Thioacetate Derivatives

, 16(7): 734 - 745

Muhammad Nouman Arif, Humaira Nadeem*, Rehan Zafar Paracha, Arif-ullah Khan, Muhammad Imran and Fawad Ali

DOI: 10.2174/1570180815666180810122226

Research Article

QSAR and Molecular Modeling Studies on a Series of Pyrrolidine Analogs Acting as BACE-1 Inhibitors

, 16(7): 746 - 760

Richa Arya, Satya Prakash Gupta*, Sarvesh Paliwal, Seema Kesar, Achal Mishra and Yenamandra Subrahmanya Prabhakar

DOI: 10.2174/1570180815666180627124422

Research Article

Structure Based Identification of Potential Inhibitors of NS3 Protein of Zika Virus

, 16(7): 761 - 774

Md. Imam Faizan, Abu Turab Naqvi , Md. Imtaiyaz Hassan, Mohd. Abdullah, Ayesha Tazeen, Zoya Shafat, Malik Hisamuddin, Aftab Alam, Shahnawaz Ali, Sher Ali, Anam Farooqui, Abu Hamza, Nazish Parveen, Farah Deeba, Anwar Ahmed and Shama Parveen*

DOI: 10.2174/1570180815666180821105012

Research Article

Pharmacophore Modeling and Docking Studies to Investigate Potential Leads for the Development of β -Secretase APP Cleavage Enzyme-1 (BACE-1) Inhibitors

, 16(7): 775 - 784

Richa Arya, Satya Prakash Gupta*, Sarvesh Paliwal, Swapnil Sharma, Kirtika Madan and Monika Chauhan

DOI: 10.2174/1570180815666181023110736

Research Article

Novel Trifluoromethylpyrazole Acyl Thiourea Derivatives: Synthesis, Antifungal Activity and Docking Study

, 16(7): 785 - 791

Han Wang, Zhi-Wen Zhai, Yan-Xia Shi, Cheng-Xia Tan, Jian-Quan Weng, Liang Han, Bao-Ju Li and Xing-Hai Liu*

DOI: 10.2174/1570180815666180704103047

Research Article

Design, Synthesis and Anti-tuberculosis Activity of Hydrazones and N-acylhydrazones Containing Vitamin B6 and Different Heteroaromatic Nucleus

, 16(7): 792 - 798

Thais Cristina Mendonça Nogueira, Lucas dos Santos Cruz, Maria Cristina Lourenço and Marcus Vinicius Nora de Souza*

DOI: 10.2174/1570180815666180627122055

Research Article

Interaction of Stigmasterol with Trypanosomal Uridylyl Transferase, Farnesyl Diphosphate Synthase and Sterol 14α-demethylase: An In Silico Prediction of Mechanism of Action

, 16(7): 799 - 807

Mohammed Auwal Ibrahim*, Murtala Bindawa Isah, Nasir Tajuddeen, Saadatu Auwal Hamza and Aminu Mohammed

DOI: 10.2174/1570180815666180711110324

Research Article

Structure Guided Molecular Docking Assisted Alignment Dependent 3DQSAR Study on Steroidal Aromatase Inhibitors (SAIs) as Anti-breast Cancer Agents

, 16(7): 808 - 817

Laxmi Banjare, Sant Kumar Verma, Akhlesh Kumar Jain and Suresh Thareja*

DOI: 10.2174/1570180815666181010101024

Research Article

Design, Synthesis and Cytotoxicity of Novel Coumarin-1,2,3-triazole-1,2,4- Oxadiazole Hybrids as Potent Anti-breast Cancer Agents

, 16(7): 818 - 824

Maryam Mohammadi-Khanaposhtani, Kiana Fahimi, Elahe Karimpour-Razkenari, Maliheh Safavi, Mohammad Mahdavi, Mina Saeedi and Tahmineh Akbarzadeh*

DOI: 10.2174/1570180815666180627121006


K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05


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