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Letters in Drug Design & Discovery

Volume 17, 12 Issues, 2020
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research


Letters in Drug Design & Discovery, Volume 16 - Number 6

Biography   Open Access

Research Article

Virtual Screening, Docking, Synthesis and Bioactivity Evaluation of Thiazolidinediones as Potential PPARγ Partial Agonists for Preparation of Antidiabetic Agents

, 16(6): 608 - 617

Beina Zhang, Mao Shu*, Chunmei Xu, Chunhong An, Rui Wang and Zhihua Lin*

DOI: 10.2174/1570180815666180827123512

Research Article

Design, Synthesis and Evaluation of Thiourea Derivatives as Antimicrobial and Antiviral Agents

, 16(6): 618 - 624

Veerasamy Ravichandran*, Sivadasan Shalini, Krishnan Suresh Kumar, Harish Rajak and Ram Kishore Agrawal

DOI: 10.2174/1570180815666180801120440

Research Article

Virtual Screening of Henna Compounds Library for Discovery of New Leads against Human Thymidine Phosphorylase, an Overexpressed Factor of Hand-Foot Syndrome

, 16(6): 625 - 636

Davood Khodabakhshi-Javinani, Azadeh Ebrahim-Habibi*, Minoo Afshar and Latifeh Navidpour*

DOI: 10.2174/1570180815666180816123233

Research Article

In Silico Prediction and Validation of Oxygen-Regulated Protein N-myc Downstream Regulated Gene 3 and Virtual Screening of Competitive Inhibitors of L-Lactate as Therapeutics

, 16(6): 637 - 644

Hongyu Cao, Yanhua Wu, Xingzhi Zhou, Xuefang Zheng and Ge Jiang *

DOI: 10.2174/1570180815666180816130621

Research Article

New Procaspase Activating Compound (PAC-1) Like Molecules as Potent Antitumoral Agents Against Lung Cancer

, 16(6): 645 - 655

Leyla Yurttaş*, Ömer Öztürk and Zerrin Cantürk

DOI: 10.2174/1570180815666180926113040

Research Article

Novel 1,3,4-Oxadiazole Fused Thiadiazole Derivatives: Synthesis and study of Anticancer Activities

, 16(6): 656 - 662

Zanjam Spandana, Reddymasu Sreenivasulu, Tadigiri MalathiRekha and Mandava Venkata Basaveswara Rao*

DOI: 10.2174/1570180816666181031125946

Research Article

Synthesis and Anti-Tumor Activity Evaluation of Novel 7-Fluoro-4-(1- Piperazinyl) Quinolines

, 16(6): 663 - 669

Dan Liu*, Aiqi Xue, Zhixin Liu, Yi Zhang, Penghui Peng and Haifeng Wang

DOI: 10.2174/1570180815666180820131036

Research Article

Exploring Energy Profiles of Protein-Protein Interactions (PPIs) Using DFT Method

, 16(6): 670 - 677

Sanket Bapat, Renu Vyas* and Muthukumarasamy Karthikeyan

DOI: 10.2174/1570180815666180815151141

Research Article   Open Access

Design and Synthesis of the Diazirine-based Clickable Photo-affinity Probe Targeting Sphingomyelin Synthase 2

, 16(6): 678 - 684

Penghui Wang, Zhining Li, Lulu Jiang, Lu Zhou* and Deyong Ye*

DOI: 10.2174/1570180816666181106154601

Research Article

Synthesis, Formulation and Analytical Method Validation of Rutin Derivative

, 16(6): 685 - 695

Murad Abualhasan*, Mohyeddin Assali, Nidal Jaradat and Tala Sarhan

DOI: 10.2174/1570180816666181108114706

Research Article

Action of Thioglycosides of 1,2,4-Triazoles and Imidazoles on the Oxidative Stress and Glycosidases in Mice with Molecular Docking

, 16(6): 696 - 710

Mahmoud Balbaa*, Doaa Awad, Ahmad Abd Elaal, Shimaa Mahsoub, Mayssaa Moharram, Omayma Sadek, Nadjet Rezki, Mohamed Reda Aouad, Mohamed El-Taher Ibrahim Badawy and El Sayed Helmy El Ashry

DOI: 10.2174/1573413715666181212150955


K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05


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