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Letters in Drug Design & Discovery

Volume 17, 12 Issues, 2020
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Contents

Letters in Drug Design & Discovery, Volume 16 - Number 5


Review Article

Potential of Nanoparticles in Combating Candida Infections

, 16(5): 478 - 491

Faizan Abul Qais, Mohd Sajjad Ahmad Khan, Iqbal Ahmad* and Abdullah Safar Althubiani


DOI: 10.2174/1570180815666181015145224



Review Article

Recent Advances in Azole Based Scaffolds as Anticandidal Agents

, 16(5): 492 - 501

Prabhuodeyara Math Gurubasavaraj* and Jasmith Shivayya Charantimath


DOI: 10.2174/1570180815666180917125916



Research Article

Phenolic Composition and Antifungal Effect of Costus cf. arabicus L Against Yeast of the Candida Genus

, 16(5): 502 - 511

Antonia Thassya Lucas Dos Santos , Antonio Júdson Targino Machado, Maria Audilene De Freitas, Irwin Rose Alencar De Menezes, Henrique Douglas Melo Coutinho, Francisco Assis Bezerra Da Cunha, Djair Dos Santos De Lima E Souza, Aline Augusti Boligon, Adeliana Silva De Oliveira, Andressa De Alencar Silva and Maria Flaviana Bezerra Morais-Braga*


DOI: 10.2174/1570180815666180827122526



Research Article

Design, Synthesis, Antimicrobial Evaluation and Molecular Modeling Study of New 2-mercaptoimidazoles (Series-III)

, 16(5): 512 - 521

Nidhi Rani and Randhir Singh*


DOI: 10.2174/1570180815666181015144431



General Research Article

Synthesis and Anticancer Activity of New Hydrazide-hydrazones and Their Pd(II) Complexes

, 16(5): 522 - 532

Bedia Kocyigit-Kaymakcioglu*, Senem Sinem Yazici, Fatih Tok, Miriş Dikmen, Selin Engür , Emine Elçin Oruc-Emre and Aysegul Iyidogan


DOI: 10.2174/1570180815666180816124102



General Research Article

Design, Synthesis and Antitumor Activity of Quinazoline Derivatives Bearing 2,3-Dihydro-indole or 1,2,3,4-Tetrahydroquinoline

, 16(5): 533 - 546

Yiqiang OuYang, Bingbing Zhao, Xiuying Chen, Caolin Wang, Hong Zhang, Shuang Jia, Wufu Zhu* and Pengwu Zheng*


DOI: 10.2174/1570180815666180801121220



General Research Article

Novel Tri-substituted Thiazoles Bearing Piperazine Ring: Synthesis and Evaluation of their Anticancer Activity

, 16(5): 547 - 555

Asaf Evrim Evren*, Leyla Yurttaş , Busra Eksellı and Gulsen Akalın-Cıftcı


DOI: 10.2174/1570180815666180731122118



General Research Article

Cytotoxicity of Sodium Arsenite-loaded Anti-HER2 Immunoliposomes Against HER2-expressing Human Breast Cancer Cell Lines

, 16(5): 556 - 562

Moslem Afrakhteh, Alireza Kheirollah, Aminollah Pourshohod, Mohammad Ali Ghaffari, Mostafa Jamalan* and Majid Zeinali


DOI: 10.2174/1570180815666180803120409



General Research Article

A Comparative Study of the Cytotoxic and Pro-apoptotic Properties of Nepeta binaloudensis

, 16(5): 563 - 569

Seyed Ahmad Emami, Hadi Al-Najjar, Javad Asili, Maryam Sadat Habibi, Amirhossein Sahebkar and Zahra Tayarani-Najaran*


DOI: 10.2174/1570180815666180918162805



General Research Article

In Silico Design of New B-Raf Kinase Type-II Inhibitors Through Combined Molecular Modeling Studies

, 16(5): 570 - 583

Weineng Zhou, Shuai Lu, Yanmin Zhang, Lingfeng Yin, Lu Zhu, Junnan Zhao, Tao Lu, Yadong Chen* and Haichun Liu*


DOI: 10.2174/1570180815666180816121628



General Research Article

Molecular Dynamics and Inhibition of MERS CoV Papain-like Protease by Small Molecule Imidazole and Aminopurine Derivatives

, 16(5): 584 - 591

Mahmoud Kandeel*, Abdallah Altaher and Mohamed Alnazawi


DOI: 10.2174/1570180815666180918161922



General Research Article

The Impacts of Some Sedative Drugs on α -Glycosidase, Acetylcholinesterase and Butyrylcholinesterase Enzymes-potential Drugs for Some Metabolic Diseases

, 16(5): 592 - 596

Ruya Kaya, Parham Taslimi*, Muhammet Emin Naldan and İlhami Gulçin


DOI: 10.2174/1570180815666180924110023



General Research Article

The Development of Tyrosyl-DNA Phosphodyesterase 1 (TDP1) Inhibitors Based on the Amines Combining Aromatic/Heteroaromatic and Monoterpenoid Moieties

, 16(5): 597 - 605

Evgenii Mozhaitsev, Evgenii Suslov*, Yuliya Demidova, Dina Korchagina, Konstantin Volcho, Alexandra Zakharenko, Inna Vasil'eva, Maksim Kupryushkin, Arina Chepanova, Daniel Moscoh Ayine-Tora, Jóhannes Reynisson, Nariman Salakhutdinov and Olga Lavrik


DOI: 10.2174/1570180816666181220121042




Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

Biography
View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05

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