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Letters in Drug Design & Discovery

Volume 16, 12 Issues, 2019
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access

Contents

Letters in Drug Design & Discovery, Volume 16 - Number 2


Research Article   Open Access

Synthesis and Biological Evaluation of Some Novel Thiophene-bearing Quinazoline Derivatives as EGFR Inhibitors

, 16(2): 102 - 110

Min Zou, Bo Jin, Yanrong Liu, Huiping Chen, Zhuangli Zhang, Changzheng Zhang, Zhihong Zhao and Liyun Zheng*


DOI: 10.2174/1570180815666180803125935



Research Article

Synthesis and Anticancer Activity of Some 1H-inden-1-one Substituted (Heteroaryl)Acetamide Derivatives

, 16(2): 111 - 118

Ahmet Cagri Karaburun, Nalan Gundogdu-Karaburun*, Leyla Yurttas, Ismail Kayagil and Seref Demirayak


DOI: 10.2174/1570180815666180606081042



Research Article

Synthesis, Molecular Docking and Biological Evaluation of Mannich Products Based on Thiophene Nucleus using Ionic Liquid

, 16(2): 119 - 126

H.M. Patel*, D.P. Rajani, M.G. Sharma and H.G. Bhatt


DOI: 10.2174/1570180815666180502123743



Research Article

The Impact of Antioxidants from the Diet on Breast Cancer Cells Monitored by Raman Microspectroscopy

, 16(2): 127 - 137

Paula Sofia Coutinho Medeiros, Ana Lúcia Marques Batista de Carvalho*, Cristina Ruano, Juan Carlos Otero and Maria Paula Matos Marques


DOI: 10.2174/1570180815666180502120804



Research Article

Indolin-2-one Derivatives: Theoretical Studies Aimed at Finding More Potent Aurora B Kinase Inhibitors

, 16(2): 138 - 152

Ítalo Antônio Fernandes, Tamiris Maria de Assis, Isael Aparecido Rosa and Elaine Fontes Ferreira da Cunha*


DOI: 10.2174/1570180815666180528090945



Research Article

QSAR and Docking Studies of DATA Analogues as HIV-1 Reverse Transcriptase Inhibitors

, 16(2): 153 - 159

Jianbo Tong*, Shan Lei, Pei Zhan, Shangshang Qin and Yang Wang


DOI: 10.2174/1570180815666180413152636



Research Article

Synthesis, Antimicrobial Evaluation and In silico Studies of Novel 2,4- disubstituted-1,3-thiazole Derivatives

, 16(2): 160 - 173

Mir Mohammad Masood, Mohammad Irfan, Shadab Alam , Phool Hasan, Aarfa Queen, Shifa Shahid, Muhammad Zahid, Amir Azam and Mohammad Abid*


DOI: 10.2174/1570180815666180502120042



Research Article

Synthesis and Antichlamydial Activity of Novel Phenazines

, 16(2): 174 - 181

Xiaofeng Bao, Xiaowei Yu, Chao Xia, Ningjing Yang, Shengju Yang* and Yu Zhao*


DOI: 10.2174/1570180815666180518112952



Research Article

Synthesis, Cytotoxic Evaluation, and Molecular Docking Studies of N-(7- hydroxy-4-methyl-2-oxoquinolin-1(2H)-yl)acetamide/benzamide Analogues

, 16(2): 182 - 193

Mohamed Jawed Ahsan*, Rupesh Kumar Kumawat, Surender Singh Jadav, Mohammed H. Geesi, Mohammed Afroz Bakht, Mohd. Zaheen Hassan, Abdulmalik Bin Saleh Al-Tamimi, Yassine Riadi , Salahuddin, Afzal Hussainc, Narayan Murthy Ganta and Habibullah Khalilullah


DOI: 10.2174/1570180815666180501160047



Research Article

The Signaling Pathways in Nitric Oxide Production by Neutrophils Exposed to N-nitrosodimethylamine

, 16(2): 194 - 199

Wioletta Ratajczak-Wrona* and Ewa Jablonska


DOI: 10.2174/1570180815666180426121503



Research Article

Design and Synthesis of Novel Thioethers Derived from 1,5-Diphenyl-6- thioxo-6,7-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones as Antiangiogenic Agents

, 16(2): 200 - 212

Ahmed Malki*, Doaa A.E Issa, Rasha Y. Elbayaa* and Hayam M.A. Ashour


DOI: 10.2174/1570180815666180518112321



Letter

Design, Synthesis and In vitro Cytotoxicity of New 1,2,3-triazol- and Nitrostyrene Hybrids as Potent Anticancer Agents

, 16(2): 213 - 219

Zahra Tashrifi, Maryam Mohammadi-khanaposhtani , Mehdi Shafiee Ardestani, Maliheh Safavi, Kurosh Rad-Moghadam*, Morteza Mehrdad, Bagher Larijani and Mohammad Mahdavi*


DOI: 10.2174/1570180815666180427151830



Review Article

Dual Acting Isatin-heterocyclic Hybrids: Recent Highlights as Promising Pharmacological Agents

, 16(2): 220 - 236

Srinubabu Maddela*, Githa Elizabeth Mathew, Della Grace Thomas Parambi, Fakhria Aljoufi and Bijo Mathew*


DOI: 10.2174/1570180815666180516102100




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