Bentham Science Logo

Track Your Manuscript:

Letters in Drug Design & Discovery

Volume 17, 12 Issues, 2020
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
Order Your Article Before PrintSubscribe to this Journal

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research


Letters in Drug Design & Discovery, Volume 16 - Number 2

Research Article   Open Access

Synthesis and Biological Evaluation of Some Novel Thiophene-bearing Quinazoline Derivatives as EGFR Inhibitors

, 16(2): 102 - 110

Min Zou, Bo Jin, Yanrong Liu, Huiping Chen, Zhuangli Zhang, Changzheng Zhang, Zhihong Zhao and Liyun Zheng*

DOI: 10.2174/1570180815666180803125935

Research Article

Synthesis and Anticancer Activity of Some 1H-inden-1-one Substituted (Heteroaryl)Acetamide Derivatives

, 16(2): 111 - 118

Ahmet Cagri Karaburun, Nalan Gundogdu-Karaburun*, Leyla Yurttas, Ismail Kayagil and Seref Demirayak

DOI: 10.2174/1570180815666180606081042

Research Article

Synthesis, Molecular Docking and Biological Evaluation of Mannich Products Based on Thiophene Nucleus using Ionic Liquid

, 16(2): 119 - 126

H.M. Patel*, D.P. Rajani, M.G. Sharma and H.G. Bhatt

DOI: 10.2174/1570180815666180502123743

Research Article

The Impact of Antioxidants from the Diet on Breast Cancer Cells Monitored by Raman Microspectroscopy

, 16(2): 127 - 137

Paula Sofia Coutinho Medeiros, Ana Lúcia Marques Batista de Carvalho*, Cristina Ruano, Juan Carlos Otero and Maria Paula Matos Marques

DOI: 10.2174/1570180815666180502120804

Research Article

Indolin-2-one Derivatives: Theoretical Studies Aimed at Finding More Potent Aurora B Kinase Inhibitors

, 16(2): 138 - 152

Ítalo Antônio Fernandes, Tamiris Maria de Assis, Isael Aparecido Rosa and Elaine Fontes Ferreira da Cunha*

DOI: 10.2174/1570180815666180528090945

Research Article

QSAR and Docking Studies of DATA Analogues as HIV-1 Reverse Transcriptase Inhibitors

, 16(2): 153 - 159

Jianbo Tong*, Shan Lei, Pei Zhan, Shangshang Qin and Yang Wang

DOI: 10.2174/1570180815666180413152636

Research Article

Synthesis, Antimicrobial Evaluation and In silico Studies of Novel 2,4- disubstituted-1,3-thiazole Derivatives

, 16(2): 160 - 173

Mir Mohammad Masood, Mohammad Irfan, Shadab Alam , Phool Hasan, Aarfa Queen, Shifa Shahid, Muhammad Zahid, Amir Azam and Mohammad Abid*

DOI: 10.2174/1570180815666180502120042

Research Article

Synthesis and Antichlamydial Activity of Novel Phenazines

, 16(2): 174 - 181

Xiaofeng Bao, Xiaowei Yu, Chao Xia, Ningjing Yang, Shengju Yang* and Yu Zhao*

DOI: 10.2174/1570180815666180518112952

Research Article

Synthesis, Cytotoxic Evaluation, and Molecular Docking Studies of N-(7- hydroxy-4-methyl-2-oxoquinolin-1(2H)-yl)acetamide/benzamide Analogues

, 16(2): 182 - 193

Mohamed Jawed Ahsan*, Rupesh Kumar Kumawat, Surender Singh Jadav, Mohammed H. Geesi, Mohammed Afroz Bakht, Mohd. Zaheen Hassan, Abdulmalik Bin Saleh Al-Tamimi, Yassine Riadi , Salahuddin, Afzal Hussainc, Narayan Murthy Ganta and Habibullah Khalilullah

DOI: 10.2174/1570180815666180501160047

Research Article

The Signaling Pathways in Nitric Oxide Production by Neutrophils Exposed to N-nitrosodimethylamine

, 16(2): 194 - 199

Wioletta Ratajczak-Wrona* and Ewa Jablonska

DOI: 10.2174/1570180815666180426121503

Research Article

Design and Synthesis of Novel Thioethers Derived from 1,5-Diphenyl-6- thioxo-6,7-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones as Antiangiogenic Agents

, 16(2): 200 - 212

Ahmed Malki*, Doaa A.E Issa, Rasha Y. Elbayaa* and Hayam M.A. Ashour

DOI: 10.2174/1570180815666180518112321


Design, Synthesis and In vitro Cytotoxicity of New 1,2,3-triazol- and Nitrostyrene Hybrids as Potent Anticancer Agents

, 16(2): 213 - 219

Zahra Tashrifi, Maryam Mohammadi-khanaposhtani , Mehdi Shafiee Ardestani, Maliheh Safavi, Kurosh Rad-Moghadam*, Morteza Mehrdad, Bagher Larijani and Mohammad Mahdavi*

DOI: 10.2174/1570180815666180427151830

Review Article

Dual Acting Isatin-heterocyclic Hybrids: Recent Highlights as Promising Pharmacological Agents

, 16(2): 220 - 236

Srinubabu Maddela*, Githa Elizabeth Mathew, Della Grace Thomas Parambi, Fakhria Aljoufi and Bijo Mathew*

DOI: 10.2174/1570180815666180516102100


K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05


Covid Resource CenterCoronaviruses-JOIN-EDITORIAL-BOARD

Related Journals

Related eBooks

eBooks Catalog