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Letters in Drug Design & Discovery

Volume 18, 12 Issues, 2021
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access


Letters in Drug Design & Discovery, Volume 16 - Number 12

Biography   Open Access

Review Article

Monobactams: A Unique Natural Scaffold of Four-Membered Ring Skeleton, Recent Development to Clinically Overcome Infections by Multidrug- Resistant Microbes

, 16(12): 1305 - 1320

Abdel Nasser El-Shorbagi* and Sachin Chaudhary

DOI: 10.2174/1570180816666190516113202

Research Article

Effects of Acute and Chronic Treatment of Novel Psychotropic Drug, 8- (Trifluoromethyl)-1, 2, 3, 4, 5-benzopentathiepin-6-amine Hydrochloride (TC-2153), on the Behavior of Zebrafish (Danio Rerio): A Comparison with Fluoxetine

, 16(12): 1321 - 1328

Alexander Kulikov, Nadezhda Sinyakova, Elizabeth Kulikova, Tatyana Khomenko, Nariman Salakhutdinov, Victor Kulikov and Konstantin Volcho*

DOI: 10.2174/1570180816666190221162952

Research Article

Biology-oriented Drug Synthesis (BIODS), Structural Characterization and Bioactivities of Novel Albendazole Derivatives

, 16(12): 1329 - 1338

Momin Khan*, Shahid Khan, Uzma Salar, Khalid Mohammed Khan, Gauhar Rehman, Naeem Gul and Iltaf Khan

DOI: 10.2174/1570180816666190221163641

Research Article

Baicalin-induced Cytotoxicity and Apoptosis in Multidrug-resistant MC3/5FU Mucoepidermoid Carcinoma Cell Line

, 16(12): 1339 - 1347

Xiaofang Xu, Qihong Li, Kaitao Yu*, Ghulam Murtaza* and Bin Liu*

DOI: 10.2174/157018081210151012121717

Research Article

Design, Synthesis and Bioactivity of Core 1 O-glycan and its Derivative on Human Gut Microbiota

, 16(12): 1348 - 1353

Huanhuan Qu*, Baixue Li, Jingyi Yang, Huaiwen Liang, Meixia Li and Kan Ding*

DOI: 10.2174/1570180816666181218143207

Research Article

Anticancer Potential of Pulicaria crispa Extract on Human Breast Cancer MDA-MB-231 Cells

, 16(12): 1354 - 1359

Ibrahim Omar Barnawi and Imran Ali*

DOI: 10.2174/1570180816666190712110224

Research Article

Synthesis and Antimicrobial Activity of Adamantyl Substituted Pyridoxine Derivatives

, 16(12): 1360 - 1369

Rail Khaziev, Nikita Shtyrlin, Roman Pavelyev, Raushan Nigmatullin, Raylya Gabbasova, Denis Grishaev, Anna Shtro, Anastasia Galochkina , Yulia Nikolaeva , Tatiana Vinogradova , Olga Manicheva, Marine Dogonadze, Oleg Gnezdilov , Evgeny Sokolovich, Petr Yablonskiy, Konstantin Balakin and Yurii Shtyrlin*

DOI: 10.2174/1570180816666190911150705


The Antiviral Effects of Sodium Phenylbutyrate Against BoHV-1 Infection In Vitro

, 16(12): 1370 - 1377

Xinye Chen, Guoqiang Zhu* and Liqian Zhu*

DOI: 10.2174/1570180816666190222155958


Design, Synthesis and Biological Evaluation of Camptothecin Conjugated with NSAIDs as Novel Dual-actin Antitumor Agents

, 16(12): 1378 - 1386

Xingchen Cai, Weiwei Huang, Yi Huang, Lihua Xia, Miao Liu, Mengke Wang, Wenchao Wang and Qingyong Li*

DOI: 10.2174/1570180816666190221103257

Letter   Open Access

Challenges in the Discovery and Optimization of mGlu2/4 Heterodimer Positive Allosteric Modulators

, 16(12): 1387 - 1394

Mark Gallant Fulton, Matthew Thomas Loch, Caroline Anne Cuoco, Alice Lambert Rodriguez, Emily Days, Paige Newton Vinson, Krystian Andrezej Kozek, Charles David Weaver, Anna Louise Blobaum, Peter Jeffrey Conn, Colleen Marie Niswender* and Craig William Lindsley*

DOI: 10.2174/1570180815666181017131349


Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Ivana Cacciatore serves as the Editor-in-Chief of the journal.

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