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Letters in Drug Design & Discovery

Volume 17, 12 Issues, 2020
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Contents

Letters in Drug Design & Discovery, Volume 16 - Number 11


Review Article

Insights Into the Explication of Potent Tyrosinase Inhibitors with Reference to Computational Studies

, 16(11): 1182 - 1193

Naima Parveen, Sharique Akhtar Ali* and Ayesha Sharique Ali


DOI: 10.2174/1570180815666180803111021



Research Article

Synthesis, Anti-proliferative Evaluation, and Molecular Docking Studies of 3-(alkylthio)-5,6-diaryl-1,2,4-triazines as Tubulin Polymerization Inhibitors

, 16(11): 1194 - 1201

Farhad Saravani, Ebrahim Saeedian Moghadam, Hafezeh Salehabadi, Seyednasser Ostad, Morteza Pirali Hamedani, Massoud Amanlou, Mohammad Ali Faramarzi and Mohsen Amini*


DOI: 10.2174/1570180815666180727114216



Research Article

Preparation and Antitubercular Activities of Palindromic Hydrazinecarbothioamides and Carbonothioic Dihydrazides

, 16(11): 1202 - 1210

Michael Joseps Hearn*, Gwendolyn Towers and Michael Henry Cynamon


DOI: 10.2174/1570180815666180727120422



Research Article

Molecular Dynamics Studies on COX-2 Protein-tyrosine Analogue Complex and Ligand-based Computational Analysis of Halo-substituted Tyrosine Analogues

, 16(11): 1211 - 1232

Ayarivan Puratchikody*, Appavoo Umamaheswari, Navabshan Irfan and Dharmarajan Sriram


DOI: 10.2174/1570180815666180627123445



Research Article

Synthesis, Antioxidant and Anti-inflammatory Activities of 5-((styrylsulfonyl) methyl)-1,3,4-Oxadiazol / Thiadiazol-2-amine Derivatives

, 16(11): 1233 - 1247

Gundala Sravya, Ummadi Nagarjuna, Venkatapuram Padmavathi, Galla Rajitha, Sakuri Chandi priya and Adivireddy Padmaja*


DOI: 10.2174/1570180816666181102114529



Research Article   Open Access

Synthesis of Phenyl- and Pyridyl-substituted Benzyloxybenzaldehydes by Suzuki-Miyaura Coupling Reactions

, 16(11): 1248 - 1257

Hedvig Bölcskei*, Andrea Német-Hanzelik, Zsófia Dubrovay, Viktor Háda and György Keglevich


DOI: 10.2174/1570180816666181106123809



Research Article

Scoring Ligand Efficiency: Potency, Ligand Efficiency and Product Ligand Efficiency within Big Data Landscape

, 16(11): 1258 - 1263

Jaroslaw Polanski*, Anna Pedrys, Roksana Duszkiewicz and Johann Gasteiger


DOI: 10.2174/1570180816666190112154505



Research Article

Recursive Partitioning Analysis and Anti-Tubercular Screening of 3- Aminopyrazine-2-Carbohydrazide Derivatives

, 16(11): 1264 - 1275

Pankaj Miniyar*, Anand Mahajan, Dattatray Anuse, Ashish Kumar, Mahesh Barmade, Dhiman Sarkar, Manisha Arkile and Vijay Khedkar


DOI: 10.2174/1570180816666190329222636



Research Article

Tyrosinase Inhibitory Activity of S-Naproxen Derivatives

, 16(11): 1276 - 1285

Ghulam Mohiuddin, Khalid Mohammed Khan*, Uzma Salar, Kanwal, Muhammad Arif Lodhi, Farida Begum and Shahnaz Perveen


DOI: 10.2174/1570180816666190611162355



Research Article

Preliminary Study on the Mechanism of Carvacrol Regulating Hepatocellular Carcinoma Based on Network Pharmacology

, 16(11): 1286 - 1295

Sha Li, Haixia Zhao* and Lidao Bao*


DOI: 10.2174/1570180816666190516105906



Research Article   Open Access

Antitumor Activity of Cyclodextrin-based Supramolecular Platinum Prodrug In vitro and In vivo

, 16(11): 1296 - 1301

Yu-Hui Zhang, Jie Wang, Siqintana Xin, Li-Juan Wang and Xianliang Sheng*


DOI: 10.2174/1570180816666190618114505




Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

Biography View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05

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