Letters in Drug Design & Discovery
Volume 18, 12 Issues, 2021
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
Contents
Letters in Drug Design & Discovery, Volume 16 - Number 1
Biography Open Access
Preface Open Access
Research Article
Copper-catalyzed Convenient Synthesis and SAR Studies of Substituted- 1,2,3-triazole as Antimicrobial Agents
, 16(1): 3 - 10Aniket P. Sarkate*, Kshipra S. Karnik, Pravin S. Wakte, Ajinkya P. Sarkate, Ashwini V. Izankar and Devanand B. Shinde
DOI: 10.2174/1570180815666180326153322
Copper-catalyzed Convenient Synthesis and SAR Studies of Substituted- 1,2,3-triazole as Antimicrobial Agents
Research Article
Development and Validation of a Robust QSAR Model for Benzothiazole Hydrazone Derivatives as Bcl-XL Inhibitors
, 16(1): 11 - 20Pawan Gupta* and Aleksandrs Gutcaits
DOI: 10.2174/1570180815666180502093039
Development and Validation of a Robust QSAR Model for Benzothiazole Hydrazone Derivatives as Bcl-XL Inhibitors
Research Article
Discovery of Hybrid Purine-quinoline Molecules and Their Cytotoxic Evaluation
, 16(1): 21 - 28Khushal M. Kapadiya and Ranjan C. Khunt*
DOI: 10.2174/1570180815666180419151742
Discovery of Hybrid Purine-quinoline Molecules and Their Cytotoxic Evaluation
Research Article
Synthesis, Nematicidal Activity and Docking Study of Novel Pyrazole-4- Carboxamide Derivatives Against Meloidogyne incognita
, 16(1): 29 - 35Long Cheng, Wen Zhao, Zhong-Hua Shen, Tian-Ming Xu, Hong-Ke Wu, Wei-Li Peng* and Xing-Hai Liu*
DOI: 10.2174/1570180815666180326150827
Synthesis, Nematicidal Activity and Docking Study of Novel Pyrazole-4- Carboxamide Derivatives Against Meloidogyne incognita
Research Article
Novel Piperazine Amides of Cinnamic Acid Derivatives as Tyrosinase Inhibitors
, 16(1): 36 - 44Zehra Tuğçe Gür, Fatma Sezer Şenol, Suhaib Shekfeh, İlkay Erdoğan Orhan , Erden Banoğlu and Burcu Çalişkan*
DOI: 10.2174/1570180815666180420105652
Novel Piperazine Amides of Cinnamic Acid Derivatives as Tyrosinase Inhibitors
Research Article
Synthesis and Cytotoxicity Studies on Novel Piperazinylacetamides
, 16(1): 45 - 51Eman Bobtaina, Enise Ece Gurdal*, Irem Durmaz, Rengul Cetin Atalay and Mine Yarim
DOI: 10.2174/1570180815666180501124009
Synthesis and Cytotoxicity Studies on Novel Piperazinylacetamides
Research Article
Genoprotective Effect of New Triazine Derivatives in Endosulfan Mediated Toxicity, an In vivo and In vitro Study
, 16(1): 52 - 57Nima Naderi, Seyed Mostafa Ghasemi Najarkolaee, Mona Modanlookordi, Mohammad Shokrzadeh and Hamid Irannejad*
DOI: 10.2174/1570180815666180420095446
Genoprotective Effect of New Triazine Derivatives in Endosulfan Mediated Toxicity, an In vivo and In vitro Study
Research Article
Synthesis of 1,3-benzoxazines Based on 2,4,4-trimethyl-7,2’,4’-trihydroxy Flavan: Antibacterial, Anti-inflammatory, Cyclooxygenase-2 Inhibition and Molecular Modelling Studies
, 16(1): 58 - 65Issam A. Mohammed, Mahmood Ahmed*, Rabia Ikram, Muhammad Muddassar, Muhammad Abdul Qadir and Khalijah Binti Awang
DOI: 10.2174/1570180815666180420100922
Synthesis of 1,3-benzoxazines Based on 2,4,4-trimethyl-7,2’,4’-trihydroxy Flavan: Antibacterial, Anti-inflammatory, Cyclooxygenase-2 Inhibition and Molecular Modelling Studies
Research Article
A New Class of Pure Estrogen Alpha Receptor Antagonists; Design, Synthesis and in-vitro Screening
, 16(1): 66 - 81Akbar John Jameera Begam, Katike Ahamed Basheer, Selvaraj Jubie*, Srikanth Jupudi, Mohammed Afzal Azam and Palanisamy Dhanabal
DOI: 10.2174/1570180815666180327124634
A New Class of Pure Estrogen Alpha Receptor Antagonists; Design, Synthesis and in-vitro Screening
Research Article
New Benzodioxole-based Pyrazoline Derivatives: Synthesis and Anticandidal, In silico ADME, Molecular Docking Studies
, 16(1): 82 - 92Ahmet Özdemir*, Belgin Sever and Mehlika Dilek Altıntop
DOI: 10.2174/1570180815666180326152726
New Benzodioxole-based Pyrazoline Derivatives: Synthesis and Anticandidal, In silico ADME, Molecular Docking Studies
Letter
Synthesis of a Series of Chalcones and Related Flavones and Evaluation of their Antibacterial and Antifungal Activities
, 16(1): 93 - 100Hind Benouda, Btissam Bouchal, Allal Challioui, Abdelkader Oulmidi, Tarik Harit, Fouad Malek, Abdelkhalek Riahi, Mohammed Bellaoui and Boufelja Bouammali *
DOI: 10.2174/1570180815666180404130430
Synthesis of a Series of Chalcones and Related Flavones and Evaluation of their Antibacterial and Antifungal Activities
Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)
Biography
University of Hradec Kralove
Hradec Kralove
Biography
Biography of K. Kuca
Kamil Kuca is working for several academic institutes (University of Hradec Kralove, Czech Republic; University Hospital Hradec Kralove, Czech republic; Florida International University, USA; Yangtze University, China; etc.). He is recently rector of the University of Hradec Kralove. He was also technology scout focused on biomedicine in the past. His research interests are toxicology, pharmacology, drug design, technology transfer, pharmacoeconomy, chemical and biological terrorism, etc. He was/is principal investigator on numerous national and international projects (EU, NATO, GACR, IGA MZ, MSMT etc.). He has published more than 350 IF research papers. He is working with several companies as a scientific consultant. He has lots of cooperators throughout the world (e.g. Korea, Croatia, United Arab Emirates, USA, France, Turkey, China, Singapore, Sweden, and Brazil). His Hindex is 36, number of citation in WoS is over 3000.
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Journal History
Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
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